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JNK Antikörper (Thr183)
MAPK8
Reaktivität: Human, Maus, Ratte, Huhn
WB, ELISA, IF, IHC (p)
Wirt: Kaninchen
Polyclonal
unconjugated
Produktnummer ABIN5960039
Produktdetails anti-JNK Antikörper
(ausblenden)
Target
Alle JNK (MAPK8) Antikörper anzeigen
JNK (MAPK8)
(Mitogen-Activated Protein Kinase 8 (MAPK8))
Bindungsspezifität
Alle Epitope für JNK Antikörper
Thr183
Reaktivität
Alle Reaktivitäten für JNK Antikörper
Human, Maus, Ratte, Huhn
Wirt
Alle Wirte für JNK Antikörper
Kaninchen
Klonalität
Alle Klonalitäten für JNK Antikörper
Polyklonal
Konjugat
Alle Konjugate für JNK Antikörper
Dieser JNK Antikörper ist unkonjugiert
Applikation
Alle Applikationen für JNK Antikörper
Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
Spezifität
MAPK8,JNK1,PRKM8,SAPK1,SAPK1C,Mitogen-activated protein kinase 8,MAP kinase 8,MAPK 8,JNK-46,Stress-activated protein kinase 1c,SAPK1c,Stress-activated protein kinase JNK1,c-Jun N-terminal kinase 1,MAPK9,JNK2,PRKM9,SAPK1A,Mi
Aufreinigung
Affinity purification
Immunogen
Synthesized peptide derived from human JNK1/2/3 around the non-phosphorylation site of Thr183.
Isotyp
IgG
Top Product
Discover our top product MAPK8 Primärantikörper
Alternativen
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anti-Mitogen-Activated Protein Kinase 8 (MAPK8) (pThr183), (pTyr185) antibody
MAPK8
Reaktivität: Human, Maus, Ratte, Hund, Kaninchen
WB, ELISA, IHC (p), FACS, IF (cc), IF (p), ICC, IHC (fro)
Wirt: Kaninchen
Polyclonal
unconjugated
anti-Mitogen-Activated Protein Kinase 8 (MAPK8) (AA 201-300) antibody
MAPK8
Reaktivität: Human, Maus, Ratte, Huhn, Hund
WB, ELISA, IHC (p), FACS, IF (cc), IF (p), IHC (fro)
Wirt: Kaninchen
Polyclonal
unconjugated
Anwendungsinformationen
(ausblenden)
Applikationshinweise
WB 1:500-1:2000, IHC 1:100-1:300, IF 1:200-1:1000, ELISA 1:10000
Beschränkungen
Nur für Forschungszwecke einsetzbar
Handhabung
(ausblenden)
Format
Liquid
Konzentration
1 mg/mL
Buffer
PBS with 0.02 % sodium azide, 0.5 % BSA and 50 % glycerol, pH 7.4
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
-20 °C
Informationen zur Lagerung
Store at -20°C. Avoid freeze / thaw cycles.
Details zu JNK
(ausblenden)
Target
JNK (MAPK8)
(Mitogen-Activated Protein Kinase 8 (MAPK8))
Andere Bezeichnung
JNK1/2/3 (MAPK8 Produkte )
Synonyme
JNK antikoerper, JNK-46 antikoerper, JNK1 antikoerper, JNK1A2 antikoerper, JNK21B1/2 antikoerper, PRKM8 antikoerper, SAPK1 antikoerper, SAPK1c antikoerper, AI849689 antikoerper, Prkm8 antikoerper, BSK antikoerper, BSK/DJNK antikoerper, Bsk antikoerper, CG5680 antikoerper, D-JNK antikoerper, D-junk antikoerper, DBSK/JNK antikoerper, DJNK antikoerper, DJNK/bsk antikoerper, Dmel\\CG5680 antikoerper, JNK/SAPK antikoerper, Jnk antikoerper, Junk antikoerper, SAPKa antikoerper, c-Jun antikoerper, dJNK antikoerper, jnk antikoerper, T10F20.15 antikoerper, jnk1 antikoerper, sapk1 antikoerper, mapk8 antikoerper, zgc:112379 antikoerper, JNKb antikoerper, mapk8b antikoerper, mitogen-activated protein kinase 8 antikoerper, Stress-activated protein kinase jnk-1 antikoerper, basket antikoerper, Protein kinase superfamily protein antikoerper, mitogen-activated protein kinase 8 L homeolog antikoerper, mitogen-activated protein kinase 8b antikoerper, mitogen-activated protein kinase 8B-like antikoerper, MAPK8 antikoerper, jnk-1 antikoerper, Mapk8 antikoerper, bsk antikoerper, ATMPK8 antikoerper, mapk8.L antikoerper, mapk8b antikoerper, LOC109094263 antikoerper
Hintergrund
C-Jun N-terminal kinases (JNKs) phosphorylate and augment transcriptional activity of c-Jun. JNKs originate from three genes that yield ten isoforms through alternative mRNA splicing, including JNK1α1,JNK1β1, JNK2α1, JNK2β1 and JNK3α1, which represent the p46 isoforms, and JNK1α2, JNK1β2, JNK2α2, JNK2β2 and JNK3β2, which represent the p54 isoforms. JNKs coordinate cell responses to stress and influence regulation of cell growth and ransformation. The human JNK1 (PRKM8, SAPK1, MAPK8) gene maps to chromosome 10q11.22 and shares 83 % amino acid identity with JNK2. JNK1 is necessary for normal activation and differentiation of CD4 helper T (TH) cells into TH1 and TH2 effector cells. Capsaicin activates JNK1 and p38 in Ras-transformed human breast epithelial cells. Nitrogen oxides (NOx) upregulate JNK1 in addition to c-Fos, c-Jun and other signaling kinases, including MEKK1 and p38.
Molekulargewicht
48kDa
Gen-ID
5599, 5601, 5602
Pathways
MAPK Signalweg , WNT Signalweg , TLR Signalweg , Fc-epsilon Rezeptor Signalübertragung , Neurotrophin Signalübertragung , Activation of Innate immune Response , Hepatitis C , Toll-Like Receptors Cascades , Signaling of Hepatocyte Growth Factor Receptor , S100 Proteine
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