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Phospholipase C gamma 2 Antikörper (AA 1201-1258)

PLCG2 Reaktivität: Human WB, IHC, ELISA, IF, FACS, ICC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN5692854
  • Target Alle Phospholipase C gamma 2 (PLCG2) Antikörper anzeigen
    Phospholipase C gamma 2 (PLCG2)
    Bindungsspezifität
    • 27
    • 18
    • 15
    • 12
    • 6
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1201-1258
    Reaktivität
    • 108
    • 53
    • 40
    • 6
    • 4
    • 4
    • 4
    • 4
    • 3
    • 1
    Human
    Wirt
    • 99
    • 9
    Kaninchen
    Klonalität
    • 99
    • 9
    Polyklonal
    Konjugat
    • 47
    • 6
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    Dieser Phospholipase C gamma 2 Antikörper ist unkonjugiert
    Applikation
    • 81
    • 37
    • 37
    • 30
    • 30
    • 18
    • 17
    • 11
    • 10
    • 6
    • 5
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF), Flow Cytometry (FACS), Immunocytochemistry (ICC)
    Verwendungszweck
    Anti-PLCG 2/PLCG2 Antibody Picoband®
    Kreuzreaktivität (Details)
    No cross-reactivity with other proteins.
    Produktmerkmale
    Anti-PLCG 2/PLCG2 Antibody Picoband® (ABIN5692854). Tested in ELISA, Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
    Immunogen
    E. coli-derived human PLCG 2 recombinant protein (Position: R1201-V1258).
    Isotyp
    IgG
    Top Product
    Discover our top product PLCG2 Primärantikörper
  • Applikationshinweise
    Western blot,0.1-0.5 μg/mL
    Immunohistochemistry (Paraffin-embedded Section),2-5 μg/mL
    Immunocytochemistry/Immunofluorescence, 5 μg/mL
    Flow Cytometry (Fixed), 1-3 μg/1x106 cells
    ELISA,0.1-0.5 μg/mL
    1. "Entrez Gene: PLCG2 phospholipase C, gamma 2 (phosphatidylinositol-specific)". 2. Hernandez D, Egan SE, Yulug IG, Fisher EM (February 1995). "Mapping the gene that encodes phosphatidylinositol-specific phospholipase C-gamma 2 in the human and the mouse". Genomics. 23 (2): 504-7.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    Konzentration
    500 μg/mL
    Buffer
    Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
  • Target
    Phospholipase C gamma 2 (PLCG2)
    Andere Bezeichnung
    PLCG2 (PLCG2 Produkte)
    Hintergrund

    Synonyms: 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2, Phosphoinositide phospholipase C-gamma-2, Phospholipase C-IV, PLC-IV, Phospholipase C-gamma-2, PLC-gamma-2, PLCG2

    Background: 1-Phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma-2 is an enzyme that in humans is encoded by the PLCG2 gene. The protein encoded by this gene is a transmembrane signaling enzyme that catalyzes the conversion of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate to 1D-myo-inositol 1,4,5-trisphosphate (IP3) and diacylglycerol (DAG) using calcium as a cofactor. IP3 and DAG are second messenger molecules important for transmitting signals from growth factor receptors and immune system receptors across the cell membrane. Mutations in this gene have been found in autoinflammation, antibody deficiency, and immune dysregulation syndrome and familial cold autoinflammatory syndrome 3.

    Molekulargewicht
    148 kDa
    Gen-ID
    5336
    UniProt
    P16885
    Pathways
    RTK Signalweg, WNT Signalweg, Fc-epsilon Rezeptor Signalübertragung, Inositol Metabolic Process, Myometrial Relaxation and Contraction, Toll-Like Receptors Cascades, VEGF Signaling, BCR Signaling
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