Telefon:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@antikoerper-online.de

Phospholipase C gamma 2 Antikörper (AA 1201-1258)

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch Phospholipase C gamma 2 in WB, IHC, ELISA, IF, FACS und ICC. Er zeigt eine Reaktivität gegenüber Human.
Produktnummer ABIN5692854

Kurzübersicht für Phospholipase C gamma 2 Antikörper (AA 1201-1258) (ABIN5692854)

Target

Alle Phospholipase C gamma 2 (PLCG2) Antikörper anzeigen
Phospholipase C gamma 2 (PLCG2)

Reaktivität

  • 121
  • 59
  • 45
  • 6
  • 4
  • 4
  • 4
  • 4
  • 3
  • 1
Human

Wirt

  • 110
  • 11
Kaninchen

Klonalität

  • 110
  • 11
Polyklonal

Konjugat

  • 57
  • 6
  • 4
  • 4
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
Dieser Phospholipase C gamma 2 Antikörper ist unkonjugiert

Applikation

  • 93
  • 40
  • 40
  • 32
  • 32
  • 23
  • 18
  • 15
  • 11
  • 9
  • 6
  • 3
  • 2
  • 2
  • 1
Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF), Flow Cytometry (FACS), Immunocytochemistry (ICC)
  • Bindungsspezifität

    • 29
    • 19
    • 16
    • 13
    • 6
    • 5
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1201-1258

    Verwendungszweck

    Anti-PLCG 2/PLCG2 Antibody Picoband®

    Kreuzreaktivität (Details)

    No cross-reactivity with other proteins.

    Produktmerkmale

    Anti-PLCG 2/PLCG2 Antibody Picoband® (ABIN5692854). Tested in ELISA, Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    Immunogen

    E. coli-derived human PLCG 2 recombinant protein (Position: R1201-V1258).

    Isotyp

    IgG
  • Applikationshinweise

    Western blot,0.1-0.5 μg/mL
    Immunohistochemistry (Paraffin-embedded Section),2-5 μg/mL
    Immunocytochemistry/Immunofluorescence, 5 μg/mL
    Flow Cytometry (Fixed), 1-3 μg/1x106 cells
    ELISA,0.1-0.5 μg/mL
    1. "Entrez Gene: PLCG2 phospholipase C, gamma 2 (phosphatidylinositol-specific)". 2. Hernandez D, Egan SE, Yulug IG, Fisher EM (February 1995). "Mapping the gene that encodes phosphatidylinositol-specific phospholipase C-gamma 2 in the human and the mouse". Genomics. 23 (2): 504-7.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Lyophilized

    Rekonstitution

    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    Konzentration

    500 μg/mL

    Buffer

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.

    Lagerung

    4 °C,-20 °C

    Informationen zur Lagerung

    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
  • Target

    Phospholipase C gamma 2 (PLCG2)

    Andere Bezeichnung

    PLCG2

    Hintergrund

    Synonyms: 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2, Phosphoinositide phospholipase C-gamma-2, Phospholipase C-IV, PLC-IV, Phospholipase C-gamma-2, PLC-gamma-2, PLCG2

    Background: 1-Phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma-2 is an enzyme that in humans is encoded by the PLCG2 gene. The protein encoded by this gene is a transmembrane signaling enzyme that catalyzes the conversion of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate to 1D-myo-inositol 1,4,5-trisphosphate (IP3) and diacylglycerol (DAG) using calcium as a cofactor. IP3 and DAG are second messenger molecules important for transmitting signals from growth factor receptors and immune system receptors across the cell membrane. Mutations in this gene have been found in autoinflammation, antibody deficiency, and immune dysregulation syndrome and familial cold autoinflammatory syndrome 3.

    Molekulargewicht

    148 kDa

    Gen-ID

    5336

    UniProt

    P16885

    Pathways

    RTK Signalweg, WNT Signalweg, Fc-epsilon Rezeptor Signalübertragung, Inositol Metabolic Process, Myometrial Relaxation and Contraction, Toll-Like Receptors Cascades, VEGF Signaling, BCR Signaling
Sie sind hier:
Chat with us!