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Rekombinanter p53 Antikörper (AA 371-380)

Name: Rekombinanter p53 Antikörper (AA 371-380)
Brand: antibodies-online
SKU: ABIN5668086
Price: 540 EUR
Availability: InStock

TP53 Reaktivität: Human, Maus, Ratte, Affe, Kaninchen WB, ELISA, IF, IHC (p), IP, IHC (fro), in vivo Wirt: Kaninchen Chimeric PAb421 unconjugated Recombinant Antibody

Western Blot using anti-p53 antibody PAb42. (Rekombinanter p53 Antikörper (AA 371-380))

Immunofluorescence staining of fixed A431 with anti-p53 antibody PAb421. (Rekombinanter p53 Antikörper (AA 371-380))

2 Abbildungen

Produktnummer ABIN5668086

Datenblatt (PDF)

Target Alle p53 (TP53) Antikörper anzeigen

p53 (TP53) (Tumor Protein P53 (TP53))

Antikörpertyp

Recombinant Antibody
Bindungsspezifität
49

39

39

38

32

28

24

24

23

22

21

20

19

19

18

18

16

16

14

13

9

8

8

8

8

7

7

7

7

7

7

7

6

6

6

5

5

5

5

4

4

4

3

3

3

3

3

3

3

3
AA 371-380
Reaktivität
863

263

217

112

48

35

33

19

10

8

7

6

4

3

3

3

2

2

2

2

1

1

1

1
Human, Maus, Ratte, Affe, Kaninchen
Wirt
647

230

6

2

1
Kaninchen
Passende Sekundärantikörper
Klonalität
601

285
Chimeric
Konjugat
484

48

37

26

25

25

24

24

22

22

22

13

13

13

13

13

12

5

5

5

5

5

5

2

2

2

2

2

2

2

1

1

1

1

1

1
Dieser p53 Antikörper ist unkonjugiert
Applikation
695

322

246

217

193

139

124

119

118

64

53

35

20

17

13

12

12

9

9

8

6

4

3

3

2

2

2

1

1

1

1

1
Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro)), In vivo Studies (in vivo)

Spezifität

Recognises the mammalian mutant and wild-type p53 protein and reacts with an epitope between amino acid residues 370 and 378 (near the C-terminus of the protein).

Kreuzreaktivität

Affe, Maus, Kaninchen, Ratte

Produktmerkmale

OriginalSpeciesName: Mouse
OriginalFormat: IgG2a

Aufreinigung

Purified antibody.

Immunogen

Synthetic peptide corresponding to aa 371-380 of human p53.

Klon

PAb421

Isotyp

IgG kappa

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Applikationshinweise

Optimal working dilution should be determined by the investigator.

Kommentare

This chimeric rabbit antibody was made using the variable domain sequences of the original murine IgG2a format, for improved compatibility with existing reagents, assays and techniques.

Beschränkungen

Nur für Forschungszwecke einsetzbar
Buffer

PBS with 0.02 % Proclin 300.

Konservierungsmittel

ProClin

Vorsichtsmaßnahmen

This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung

4 °C,-20 °C

Informationen zur Lagerung

Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
Target

p53 (TP53) (Tumor Protein P53 (TP53))

Andere Bezeichnung

p53 (TP53 Produkte)

Synonyme

BCC7 antikoerper, LFS1 antikoerper, P53 antikoerper, TRP53 antikoerper, p53 antikoerper, Trp53 antikoerper, brp53 antikoerper, drp53 antikoerper, etID22686.5 antikoerper, fb40d06 antikoerper, wu:fb40d06 antikoerper, zgc:111919 antikoerper, Tp53 antikoerper, bbl antikoerper, bfy antikoerper, bhy antikoerper, p44 antikoerper, tp53 antikoerper, Xp53 antikoerper, TP53 antikoerper, tumor protein p53 antikoerper, cellular tumor antigen p53 antikoerper, transformation related protein 53 antikoerper, tumor protein p53 L homeolog antikoerper, TP53 antikoerper, CpipJ_CPIJ002758 antikoerper, Tp53 antikoerper, tp53 antikoerper, Trp53 antikoerper, tp53.L antikoerper

Hintergrund

Tumor suppressor p53, Cellular tumor antigen p53

UniProt

P04637

Pathways

p53 Signalweg, MAPK Signalweg, PI3K-Akt Signalweg, Apoptose, AMPK Signaling, Chromatin Binding, ER-Nucleus Signaling, Positive Regulation of Endopeptidase Activity, Hepatitis C, Protein targeting to Nucleus, Autophagie, Warburg Effekt