Rekombinanter p53 Antikörper (AA 371-380)
Kurzübersicht für Rekombinanter p53 Antikörper (AA 371-380) (ABIN5668086)
Target
Alle p53 (TP53) Antikörper anzeigenAntikörpertyp
Reaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Bindungsspezifität
- AA 371-380
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Verwendungszweck
- Anti-p53 [PAb421], Rabbit IgG, kappa
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Spezifität
- Recognises the mammalian mutant and wild-type p53 protein and reacts with an epitope between amino acid residues 370 and 378 (near the C-terminus of the protein), corresponding to the sequence "KKGQSTSRHK".
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Kreuzreaktivität
- Affe, Maus, Kaninchen, Ratte
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Produktmerkmale
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Original Species of Ab: Mouse
Original Format of Ab: IgG2a
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Aufreinigung
- Protein A affinity purified
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Immunogen
- Synthetic peptide corresponding to aa 371-380 of human p53.
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Isotyp
- IgG kappa
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Kommentare
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This chimeric rabbit antibody was made using the variable domain sequences of the original murine IgG2a format, for improved compatibility with existing reagents, assays and techniques.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 1 mg/mL
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Buffer
- PBS with 0.02 % Proclin 300.
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Konservierungsmittel
- ProClin
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Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
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- p53 (TP53) (Tumor Protein P53 (TP53))
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Andere Bezeichnung
- p53
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Hintergrund
- Tumor suppressor p53, Cellular tumor antigen p53
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UniProt
- P04637
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Pathways
- p53 Signalweg, MAPK Signalweg, PI3K-Akt Signalweg, Apoptose, AMPK Signaling, Chromatin Binding, ER-Nucleus Signaling, Positive Regulation of Endopeptidase Activity, Hepatitis C, Protein targeting to Nucleus, Autophagie, Warburg Effekt
Target
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