Rekombinanter p53 Antikörper (AA 371-380)
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- Target Alle p53 (TP53) Antikörper anzeigen
- p53 (TP53) (Tumor Protein P53 (TP53))
- Antikörpertyp
- Recombinant Antibody
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Bindungsspezifität
- AA 371-380
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Reaktivität
- Human, Maus, Ratte, Affe, Kaninchen
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser p53 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro)), In vivo Studies (in vivo)
- Verwendungszweck
- Anti-p53 [PAb421], Mouse IgG2a, kappa
- Spezifität
- Recognises the mammalian mutant and wild-type p53 protein and reacts with an epitope between amino acid residues 370 and 378 (near the C-terminus of the protein), corresponding to the sequence "KKGQSTSRHK".
- Kreuzreaktivität
- Affe, Maus, Kaninchen, Ratte
- Produktmerkmale
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Original Species of Ab: Mouse
Original Format of Ab: IgG2a
- Aufreinigung
- Protein A affinity purified
- Immunogen
- Synthetic peptide corresponding to aa 371-380 of human p53.
- Klon
- PAb421
- Isotyp
- IgG2a kappa
- Top Product
- Discover our top product TP53 Primärantikörper
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- Applikationshinweise
- Optimal working dilution should be determined by the investigator.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Konzentration
- 1 mg/mL
- Buffer
- PBS with 0.02 % Proclin 300.
- Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C,-20 °C
- Informationen zur Lagerung
- Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
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- Target
- p53 (TP53) (Tumor Protein P53 (TP53))
- Andere Bezeichnung
- p53 (TP53 Produkte)
- Hintergrund
- Tumor suppressor p53, Cellular tumor antigen p53
- UniProt
- P04637
- Pathways
- p53 Signalweg, MAPK Signalweg, PI3K-Akt Signalweg, Apoptose, AMPK Signaling, Chromatin Binding, ER-Nucleus Signaling, Positive Regulation of Endopeptidase Activity, Hepatitis C, Protein targeting to Nucleus, Autophagie, Warburg Effekt
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