MAP3K7 Antikörper (AA 471-579)

Produktnummer ABIN5542527

Der Maus-Monoklonal Anti-MAP3K7-Antikörper wurde für ELISA validiert. Er ist geeignet zum Nachweis von MAP3K7 in Proben aus Human. }

Kurzübersicht für MAP3K7 Antikörper (AA 471-579) (ABIN5542527)

Target: MAP3K7 (Mitogen-Activated Protein Kinase Kinase Kinase 7 (MAP3K7))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser MAP3K7 Antikörper ist unkonjugiert

Applikation: ELISA

Klon: 3E8H4

Produktdetails anti-MAP3K7 Antikörper

Bindungsspezifität: AA 471-579

Verwendungszweck: MAP3K7 Antibody

Aufreinigung: Purified antibody

Immunogen: Purified recombinant fragment of human MAP3K7 (AA: 471-579) expressed in E. Coli.

Isotyp: IgG2a

Anwendungsinformationen

Applikationshinweise: ELISA: 1/10000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide. and 0.5 % protein stabilizer

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Details zu MAP3K7

Target: MAP3K7 (Mitogen-Activated Protein Kinase Kinase Kinase 7 (MAP3K7))

Andere Bezeichnung: MAP3K7

Hintergrund: The protein encoded by this gene is a member of the serine/threonine protein kinase family. This kinase mediates the signaling transduction induced by TGF beta and morphogenetic protein (BMP), and controls a variety of cell functions including transcription regulation and apoptosis. In response to IL-1, this protein forms a kinase complex including TRAF6, MAP3K7P1/TAB1 and MAP3K7P2/TAB2, this complex is required for the activation of nuclear factor kappa B. This kinase can also activate MAPK8/JNK, MAP2K4/MKK4, and thus plays a role in the cell response to environmental stresses. Four alternatively spliced transcript variants encoding distinct isoforms have been reported.

Molekulargewicht: 67.2 kDa

Gen-ID: 6885

UniProt: O43318

Pathways: NF-kappaB Signalweg, T-Zell Rezeptor Signalweg, TLR Signalweg, Fc-epsilon Rezeptor Signalübertragung, Activation of Innate immune Response, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Tube Formation, Toll-Like Receptors Cascades, BCR Signaling, Ubiquitin Proteasome Pathway