MAPK10 Antikörper (AA 180-329)

Produktnummer ABIN5542487

Dieser Maus Monoklonal Antikörper erkennt spezifisch MAPK10 in WB und ELISA. Er zeigt eine Reaktivität gegenüber Human und Ratte.

Kurzübersicht für MAPK10 Antikörper (AA 180-329) (ABIN5542487)

Target: MAPK10 (Mitogen-Activated Protein Kinase 10 (MAPK10))

Reaktivität: Human, Ratte

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser MAPK10 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Klon: 2B10H12

Produktdetails anti-MAPK10 Antikörper

Bindungsspezifität: AA 180-329

Verwendungszweck: MAPK10 Antibody

Aufreinigung: Purified antibody

Immunogen: Purified recombinant fragment of human MAPK10 (AA: 180-329) expressed in E. Coli.

Isotyp: IgG2a

Anwendungsinformationen

Applikationshinweise: ELISA: 1/10000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Details zu MAPK10

Target: MAPK10 (Mitogen-Activated Protein Kinase 10 (MAPK10))

Andere Bezeichnung: MAPK10

Hintergrund: The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as integration points for multiple biochemical signals and are involved in a wide variety of cellular processes, such as proliferation, differentiation, transcription regulation and development. This kinase is specifically expressed in a subset of neurons in the nervous system and is activated by threonine and tyrosine phosphorylation. Targeted deletion of this gene in mice suggests that it may have a role in stress-induced neuronal apoptosis. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. A recent study provided evidence for translational readthrough in this gene and expression of an additional C-terminally extended isoform via the use of an alternative in-frame translation termination codon.

Molekulargewicht: 52.6 kDa

UniProt: P53779

Pathways: MAPK Signalweg, WNT Signalweg, TLR Signalweg, Fc-epsilon Rezeptor Signalübertragung, Activation of Innate immune Response, Hepatitis C, Toll-Like Receptors Cascades