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MAPK10 Antikörper (AA 28-233)

MAPK10 Reaktivität: Human, Maus WB, ELISA, ICC Wirt: Maus Monoclonal 10E4A4 unconjugated
Produktnummer ABIN1724701
  • Target Alle MAPK10 Antikörper anzeigen
    MAPK10 (Mitogen-Activated Protein Kinase 10 (MAPK10))
    Bindungsspezifität
    • 15
    • 10
    • 8
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 28-233
    Reaktivität
    • 60
    • 49
    • 33
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Maus
    Wirt
    • 64
    • 7
    • 3
    Maus
    Klonalität
    • 58
    • 18
    Monoklonal
    Konjugat
    • 31
    • 9
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser MAPK10 Antikörper ist unkonjugiert
    Applikation
    • 44
    • 37
    • 25
    • 13
    • 13
    • 9
    • 7
    • 4
    • 4
    • 4
    • 2
    • 2
    • 2
    • 1
    Western Blotting (WB), ELISA, Immunocytochemistry (ICC)
    Aufreinigung
    purified
    Immunogen
    Purified recombinant fragment of human MAPK10 (aa28-233) expressed in E. coli.
    Klon
    10E4A4
    Isotyp
    IgG1
    Top Product
    Discover our top product MAPK10 Primärantikörper
  • Applikationshinweise
    ELISA: 1:10000, WB: 1:500 - 1:2000, ICC: 1:200 - 1:1000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Ascitic fluid containing 0.03 % sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    4°C, -20°C for long term storage
  • Tamma, Kalyanaraman, Pahwa, Dominguez, Modesto: "The lectin jacalin induces phosphorylation of ERK and JNK in CD4+ T cells." in: Journal of leukocyte biology, Vol. 73, Issue 5, pp. 682-8, (2003) (PubMed).

    Kinet, Bernard, Mongellaz, Perreau, Goldman, Taylor: "gp120-mediated induction of the MAPK cascade is dependent on the activation state of CD4(+) lymphocytes." in: Blood, Vol. 100, Issue 7, pp. 2546-53, (2002) (PubMed).

  • Target
    MAPK10 (Mitogen-Activated Protein Kinase 10 (MAPK10))
    Andere Bezeichnung
    MAPK10 (MAPK10 Produkte)
    Synonyme
    MAPK10 antikoerper, zgc:123234 antikoerper, DKFZp459H0638 antikoerper, Jnk3 antikoerper, SAPKC antikoerper, SAPb antikoerper, Serk2 antikoerper, JNK3 antikoerper, JNK3A antikoerper, PRKM10 antikoerper, SAPK1b antikoerper, p493F12 antikoerper, p54bSAPK antikoerper, C230008H04Rik antikoerper, JNK3B1 antikoerper, JNK3B2 antikoerper, SAPK(beta) antikoerper, ATMPK10 antikoerper, MAP kinase 10 antikoerper, mitogen-activated protein kinase 8 S homeolog antikoerper, mitogen-activated protein kinase 10 antikoerper, mitogen activated protein kinase 10 antikoerper, MAP kinase 10 antikoerper, mapk8.S antikoerper, MAPK10 antikoerper, mapk10 antikoerper, Mapk10 antikoerper, MPK10 antikoerper
    Hintergrund

    Description: MAPK10: mitogen-activated protein kinase 10, also known as JNK3, JNK3A, PRKM10, p54bSAPK. Entrez Protein NP_002744. It is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This protein is a neuronal-specific form of c-Jun N-terminal kinases (JNKs). Through its phosphorylation and nuclear localization, this kinase plays regulatory roles in the signaling pathways during neuronal apoptosis. Beta-arrestin 2, a receptor-regulated MAP kinase scaffold protein, is found to interact with, and stimulate the phosphorylation of this kinase by MAP kinase kinase 4 (MKK4). Cyclin-dependent kianse 5 can phosphorylate, and inhibit the activity of this kinase, which may be important in preventing neuronal apoptosis. Four alternatively spliced transcript variants encoding distinct isoforms have been reported.

    Aliases: JNK3, JNK3A, PRKM10, p54bSAPK

    Molekulargewicht
    53 kDa
    Gen-ID
    5602
    NCBI Accession
    NP_002744
    HGNC
    5602
    Pathways
    MAPK Signalweg, WNT Signalweg, TLR Signalweg, Fc-epsilon Rezeptor Signalübertragung, Activation of Innate immune Response, Hepatitis C, Toll-Like Receptors Cascades
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