Phospholipase C gamma 2 Antikörper (Middle Region)

Produktnummer ABIN5514741

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch Phospholipase C gamma 2 in WB. Er zeigt eine Reaktivität gegenüber Human, Ratte, Maus, Rind (Kuh), Hund, Pferd, Kaninchen und Meerschweinchen.

Kurzübersicht für Phospholipase C gamma 2 Antikörper (Middle Region) (ABIN5514741)

Target: Phospholipase C gamma 2 (PLCG2)

Reaktivität: Human, Ratte, Maus, Rind (Kuh), Hund, Pferd, Kaninchen, Meerschweinchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Phospholipase C gamma 2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-Phospholipase C gamma 2 Antikörper

Bindungsspezifität: Middle Region

Sequenz: ETHLRCAEFE LRLTDPVPNP NPHESKPWYY DSLSRGEAED MLMRIPRDGA

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 92%, Human: 100%, Mouse: 100%, Rabbit: 92%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against PLCG2. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of Human PLCG2

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu Phospholipase C gamma 2

Target: Phospholipase C gamma 2 (PLCG2)

Andere Bezeichnung: PLCG2

Hintergrund: The protein encoded by this gene is a transmembrane signaling enzyme that catalyzes the conversion of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate to 1D-myo-inositol 1,4,5-trisphosphate (IP3) and diacylglycerol (DAG), using calcium as a cofactor. IP3 and DAG are second messenger molecules important for transmitting signals from growth factor receptors and immune system receptors across the cell membrane.

Alias Symbols: PLCG2,

Protein Interaction Partner: UBC, ZNF512B, ERBB2, EGFR, PRKCA, PLD1, IRS1, BLNK, LAT2, LIME1, GAB2, DAPP1, PRKD1, CBLB, GAB1, KHDRBS1, LAT, SH3BP2, LCP2, TEC, SHC1, PLCG2, SYK, BTK, KDR, BLK, ITK, LYN, FLT1, NPM1, LCK, JAK2, JAK1, FCER1G, HCK, FYN, EPOR, CD19, PLXNB1, VAV1, PTPN11,

Protein Size: 1265

Gen-ID: 5336

NCBI Accession: NM_002661, NP_002652

UniProt: P16885

Pathways: RTK Signalweg, WNT Signalweg, Fc-epsilon Rezeptor Signalübertragung, Inositol Metabolic Process, Myometrial Relaxation and Contraction, Toll-Like Receptors Cascades, VEGF Signaling, BCR Signaling