TRAF3 Antikörper (AA 490-517)

Produktnummer ABIN3029150

Der Kaninchen Polyklonal Anti-TRAF3-Antikörper wurde für WB und ELISA validiert. Er ist geeignet, TRAF3 in Proben von Human und Maus zu detektieren.

Kurzübersicht für TRAF3 Antikörper (AA 490-517) (ABIN3029150)

Target: TRAF3 (TNF Receptor-Associated Factor 3 (TRAF3))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TRAF3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-TRAF3 Antikörper

Bindungsspezifität: AA 490-517

Aufreinigung: Antigen affinity purified

Immunogen: A portion of amino acids 490-517 from the human protein was used as the immunogen for this TRAF3 antibody.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Titration of the TRAF3 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot the TRAF3 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Details zu TRAF3

Target: TRAF3 (TNF Receptor-Associated Factor 3 (TRAF3))

Andere Bezeichnung: TRAF3

Hintergrund: The protein encoded by this gene is a member of the TNF receptor associated factor (TRAF) protein family. TRAF proteins associate with, and mediate the signal transduction from, members of the TNF receptor (TNFR) superfamily. This protein participates in the signal transduction of CD40, a TNFR family member important for the activation of the immune response. This protein is found to be a critical component of the lymphotoxin-beta receptor (LTbetaR) signaling complex, which induces NF-kappaB activation and cell death initiated by LTbeta ligation. Epstein-Barr virus encoded latent infection membrane protein-1 (LMP1) can interact with this and several other members of the TRAF family, which may be essential for the oncogenic effects of LMP1. Three alternatively spliced transcript variants encoding two distinct isoforms have been reported.

UniProt: Q13114

Pathways: NF-kappaB Signalweg, Apoptose, TLR Signalweg, Activation of Innate immune Response, Hepatitis C, Toll-Like Receptors Cascades