IL-1 beta Antikörper (AA 148-174)

Produktnummer ABIN3031434

Dieses Anti-IL-1 beta-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von IL-1 beta in WB, IHC, ELISA und FACS. Geeignet für Human.

Kurzübersicht für IL-1 beta Antikörper (AA 148-174) (ABIN3031434)

Target: IL-1 beta (IL1B) (Interleukin 1, beta (IL1B))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser IL-1 beta Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Flow Cytometry (FACS)

Produktdetails anti-IL-1 beta Antikörper

Bindungsspezifität: AA 148-174

Kreuzreaktivität (Details): Expected species reactivity: Primate, Rabbit

Aufreinigung: Antigen affinity purified

Immunogen: A portion of amino acids 148-174 from the human protein was used as the immunogen for this IL-1B antibody.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Titration of the IL-1B antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:10-1:50,Flow Cytometry: 1:10-1:50

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot the IL-1B antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Details zu IL-1 beta

Target: IL-1 beta (IL1B) (Interleukin 1, beta (IL1B))

Andere Bezeichnung: IL-1B

Hintergrund: IL1B is produced by activated macrophages, IL-1 stimulates thymocyte proliferation by inducing IL-2 release, B-cell maturation and proliferation, and fibroblast growth factor activity. IL-1 proteins are involved in the inflammatory response, being identified as endogenous pyrogens, and are reported to stimulate the release of prostaglandin and collagenase from synovial cells. [UniProt]

UniProt: P01584

Pathways: NF-kappaB Signalweg, Interferon-gamma Pathway, TLR Signalweg, Negative Regulation of Hormone Secretion, Cellular Response to Molecule of Bacterial Origin, Carbohydrate Homeostasis, Glycosaminoglycan Metabolic Process, Myometrial Relaxation and Contraction, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Autophagie, Cancer Immune Checkpoints, Inflammasome