Bcl-2 Antikörper (AA 144-171)
Kurzübersicht für Bcl-2 Antikörper (AA 144-171) (ABIN3030094)
Target
Alle Bcl-2 (BCL2) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 144-171
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Kreuzreaktivität (Details)
- Expected species reactivity: Bovine, Chicken, Hamster, Mouse, Rat
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Aufreinigung
- Antigen affinity purified
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Immunogen
- A portion of amino acids 144-171 from the human protein was used as the immunogen for this Bcl-2 antibody.
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Isotyp
- Ig Fraction
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anti-B-Cell CLL/lymphoma 2 (BCL2) (N-Term) antibody
BCL2 Reaktivität: Human WB, IF, IHC (p), ICC Wirt: Kaninchen Polyclonal unconjugated
anti-B-Cell CLL/lymphoma 2 (BCL2) (AA 2-211) antibodyBCL2 Reaktivität: Human WB, IHC, IF, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-B-Cell CLL/lymphoma 2 (BCL2) (AA 101-160) antibodyBCL2 Reaktivität: Human, Maus, Ratte, Kaninchen, Rind (Kuh), Huhn, Bakterien WB, FACS, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
anti-B-Cell CLL/lymphoma 2 (BCL2) (AA 75-110) antibodyBCL2 Reaktivität: Human WB, IF, IHC (p) Wirt: Kaninchen Polyclonal RB04684 unconjugated
anti-B-Cell CLL/lymphoma 2 (BCL2) antibodyBCL2 Reaktivität: Human WB, IHC, IP Wirt: Kaninchen Monoclonal unconjugated
anti-B-Cell CLL/lymphoma 2 (BCL2) (AA 2-211) antibodyBCL2 Reaktivität: Human WB, IHC, IP, ICC Wirt: Maus Monoclonal D1 unconjugated
anti-B-Cell CLL/lymphoma 2 (BCL2) (AA 41-54) antibodyBCL2 Reaktivität: Human WB, FACS, IP, IHC (p), ICC, IHC (fro) Wirt: Maus Monoclonal Bcl-2-100 unconjugated
anti-B-Cell CLL/lymphoma 2 (BCL2) (AA 41-54) antibody (PE)BCL2 Reaktivität: Human ICFC Wirt: Maus Monoclonal Bcl-2-100 PE
anti-B-Cell CLL/lymphoma 2 (BCL2) (AA 41-54) antibodyBCL2 Reaktivität: Human WB, IHC, FACS, IF, StM, ISt Wirt: Maus Monoclonal 100-D5 unconjugated
anti-B-Cell CLL/lymphoma 2 (BCL2) antibodyBCL2 Reaktivität: Human WB, IHC, StM Wirt: Kaninchen Monoclonal BCL2-2210R unconjugated Recombinant Antibody
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Applikationshinweise
- The stated application concentrations are suggested starting amounts. Titration of the Bcl-2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- In 1X PBS pH 7.4 with 0.09 % sodium azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Can be stored at 4°C for one month. For long term, aliquot the Bcl-2 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- Bcl-2 (BCL2) (B-Cell CLL/lymphoma 2 (BCL2))
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Andere Bezeichnung
- Bcl-2
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Hintergrund
- Bcl-2 suppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells. Regulates cell death by controlling the mitochondrial membrane permeability. Appears to function in a feedback loop system with caspases. Inhibits caspase activity either by preventing the release of cytochrome c from the mitochondria and/or by binding to the apoptosis-activating factor (APAF-1). [UniProt]
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UniProt
- P10415
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Pathways
- MAPK Signalweg, PI3K-Akt Signalweg, Apoptose, Caspase Kaskade in der Apoptose, Regulation of Muscle Cell Differentiation, Cell-Cell Junction Organization, Skeletal Muscle Fiber Development, Autophagie, Smooth Muscle Cell Migration, Negative Regulation of intrinsic apoptotic Signaling
Target
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