LY9 Antikörper

Produktnummer ABIN492431

Produktdetails anti-LY9 Antikörper

Target: LY9 (CD229) (Lymphocyte Antigen 9 (CD229))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser LY9 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunoprecipitation (IP), Flow Cytometry (FACS), Functional Studies (Func), Immunofluorescence (IF)

Spezifität: The antibody recognizes CD229 / Ly9, a 100-120 kDa cell surface glycoprotein expressed on T and B cells.

Kreuzreaktivität (Details): Species reactivity (tested):Human

Produktmerkmale: Synonyms: Ly-9, T-lymphocyte surface antigen Ly-9, Lymphocyte antigen 9

Aufreinigung: Protein A affinity chromatography

Reinheit: > 95 % by SDS-PAGE

Immunogen: CD299-transfected 300. 19 pre-B cell line

Klon: HLy9-25

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Flow cytometry: Use peripheral blood lymphocytes as positive control. Immunoprecipitation. Western blot. Immunocytochemistry. Functional Application.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.4

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer. Avoid repeatedfreezing and thawing.
Shelf life: one year from despatch.

Haltbarkeit: 12 months

Details zu LY9

Target: LY9 (CD229) (Lymphocyte Antigen 9 (CD229))

Andere Bezeichnung: CD229 / LY9 (CD229 Produkte)

Hintergrund: CD229 (Ly9) is a cell surface receptor of the CD150 family, which includes also e.g. CD48 and CD224. Receptors of this family regulate cytokine production and cytotoxicity of lymphocytes and NK cells. High levels of CD229 are found on T and B cells, where its expression increases during their maturation. It is absent on granulocytes, bone marrow-derived dendritic cells, platelets and erythrocytes. CD229 has been also reported on mouse monocytes and NK cells. CD229 interacts homophilically through its N-terminal domain and localizes to the contact site between T cells and antigen presenting B cells during antigen-dependent immune synapse formation.Synonyms: Ly-9, Lymphocyte antigen 9, T-lymphocyte surface antigen Ly-9

Gen-ID: 4063

UniProt: Q9HBG7

Pathways: BCR Signaling