IL-1 beta Antikörper
Kurzübersicht für IL-1 beta Antikörper (ABIN4911038)
Target
Alle IL-1 beta (IL1B) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Kreuzreaktivität
- Human
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Aufreinigung
- Mouse monoclonal antibody supplied in crude ascites with 0.09% (W/V) sodium azide.
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Immunogen
- This IL1B antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 148-174 amino acids from the Central region of human IL1B.
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Isotyp
- IgG1
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Applikationshinweise
- WB 1:300-5000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 0.5 μg/μL
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Buffer
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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Konservierungsmittel
- ProClin
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Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C for 12 months.
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Haltbarkeit
- 12 months
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- IL-1 beta (IL1B) (Interleukin 1, beta (IL1B))
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Andere Bezeichnung
- IL1B
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Hintergrund
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Synonyms: IL-1, IL1F2, IL1-BETA, Interleukin-1 beta, IL-1 beta, Catabolin, IL1B
Background: Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B-cell activation and antibody production, and fibroblast proliferation and collagen production. Promotes Th17 differentiation of T-cells.
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Gen-ID
- 3553
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UniProt
- P01584
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Pathways
- NF-kappaB Signalweg, Interferon-gamma Pathway, TLR Signalweg, Negative Regulation of Hormone Secretion, Cellular Response to Molecule of Bacterial Origin, Carbohydrate Homeostasis, Glycosaminoglycan Metabolic Process, Myometrial Relaxation and Contraction, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Autophagie, Cancer Immune Checkpoints, Inflammasome
Target
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