Phospholipase C gamma 2 Antikörper (pTyr753)

Produktnummer ABIN362188

Produktdetails anti-Phospholipase C gamma 2 Antikörper

Target: Phospholipase C gamma 2 (PLCG2)

Bindungsspezifität: pTyr753

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Phospholipase C gamma 2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF)

Spezifität: The antibody detects endogenous level of PLCg2 only when phosphorylated at tyrosine 753.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography usingepitope-specific phosphopeptide. The antibody against non-phosphopeptide was removedby chromatogramphy using non-phosphopeptide corresponding to the phosphorylation site.

Immunogen: Peptide sequence around phosphorylation site of pTyr753 (S-L-Y (p) -D-V) derived from Human PLCg2. Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western blotting: 1:500-1:1000
Immunofluorescence: 1:100-1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.

Details zu Phospholipase C gamma 2

Target: Phospholipase C gamma 2 (PLCG2)

Andere Bezeichnung: PLCgamma2 (PLCG2 Produkte)

Synonyme: PLCgamma2 antikoerper, Plcg-2 antikoerper, APLAID antikoerper, FCAS3 antikoerper, phospholipase C, gamma 2 antikoerper, phospholipase C gamma 2 antikoerper, phospholipase C, gamma 2 (phosphatidylinositol-specific) antikoerper, Plcg2 antikoerper, PLCG2 antikoerper

Hintergrund: The production of the second messenger molecules diacylglycerol. (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. It is a crucial enzyme in transmembrane signaling.

Molekulargewicht: 150 kDa

NCBI Accession: NP_002652

UniProt: P16885

Pathways: RTK Signalweg, WNT Signalweg, Fc-epsilon Rezeptor Signalübertragung, Inositol Metabolic Process, Myometrial Relaxation and Contraction, Toll-Like Receptors Cascades, VEGF Signaling, BCR Signaling