Bcl-2 Antikörper

Produktnummer ABIN306555

Der Maus Monoklonal anti-Bcl-2 Antikörper (Klon 10C4) (ABIN306555) detektiert spezifisch Bcl-2 in WB, IHC und IP. Dieser Antikörper reagiert spezifisch mit Proben aus Maus.

Kurzübersicht für Bcl-2 Antikörper (ABIN306555)

Target: Bcl-2 (BCL2) (B-Cell CLL/lymphoma 2 (BCL2))

Reaktivität: Maus

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Bcl-2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP)

Klon: 10C4

Produktdetails anti-Bcl-2 Antikörper

Kreuzreaktivität: Human

Produktmerkmale: mbcl2, bcl2, mouse anti mouse bcl2,The immunogen for the anti-human p16 was a recombinant full length p16 protein recognizing a 16 kDa protein. The p16ink4a tumor suppressor protein shows no cross reactivity with the closely related inhibitors such as p15ink4b and p18ink4c. p16ink4a is a specific inhibitor of cdk4/cdk6, and is a tumor suppressor involved in the pathogenesis of a number of malignancies including melanoma and lung carcinoma. It can be used in immunohistochemistry as an indicator of HPV infection in cervical and head and neck (pre)malignancies.

Aufreinigung: Protein A/G Chromatography

Immunogen: A recombinant full length p16 protein recognizing a 16kDa protein

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Applications: Western Blot, Immunoflurescence, Immunoprecipitation (co-precipitates cdk4/cdk6)

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: Provided as solution in phosphate buffered saline with 0.08 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Product should be stored at -20°C. Aliquot to avoid freeze/thaw cycles

Details zu Bcl-2

Target: Bcl-2 (BCL2) (B-Cell CLL/lymphoma 2 (BCL2))

Andere Bezeichnung: bcl-2

Pathways: MAPK Signalweg, PI3K-Akt Signalweg, Apoptose, Caspase Kaskade in der Apoptose, Regulation of Muscle Cell Differentiation, Cell-Cell Junction Organization, Skeletal Muscle Fiber Development, Autophagie, Smooth Muscle Cell Migration, Negative Regulation of intrinsic apoptotic Signaling