Bcl-2 Antikörper
Kurzübersicht für Bcl-2 Antikörper (ABIN306549)
Target
Alle Bcl-2 (BCL2) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Isotyp
- IgG
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Bcl-2 (BCL2) (B-Cell CLL/lymphoma 2 (BCL2))
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Andere Bezeichnung
- bcl-2
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Hintergrund
- Human hematopoetic malignancies are often characterized by gene rearrangements that deregulate gene expression. Antibodies to human bcl-2 (B cell leukemia/lymphoma 2) are directed against the gene isolated at the chromosomal breakpoint t(14,18) Bcl-2 which suppress programmed cell death (apoptosis) and appears to be modulated by association with bax, a cell death promoter. Synonyms: hbcl2, sheep anti human bcl 2, bcl-2.
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UniProt
- P10415
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Pathways
- MAPK Signalweg, PI3K-Akt Signalweg, Apoptose, Caspase Kaskade in der Apoptose, Regulation of Muscle Cell Differentiation, Cell-Cell Junction Organization, Skeletal Muscle Fiber Development, Autophagie, Smooth Muscle Cell Migration, Negative Regulation of intrinsic apoptotic Signaling
Target
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