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Phospholipase C gamma 2 Antikörper (AA 1-300)

Dieses Anti-Phospholipase C gamma 2-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von Phospholipase C gamma 2 in WB und IF. Geeignet für Human.
Produktnummer ABIN3023145

Kurzübersicht für Phospholipase C gamma 2 Antikörper (AA 1-300) (ABIN3023145)

Target

Alle Phospholipase C gamma 2 (PLCG2) Antikörper anzeigen
Phospholipase C gamma 2 (PLCG2)

Reaktivität

  • 121
  • 59
  • 45
  • 6
  • 4
  • 4
  • 4
  • 4
  • 3
  • 1
Human

Wirt

  • 110
  • 11
Kaninchen

Klonalität

  • 110
  • 11
Polyklonal

Konjugat

  • 57
  • 6
  • 4
  • 4
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
Dieser Phospholipase C gamma 2 Antikörper ist unkonjugiert

Applikation

  • 93
  • 40
  • 40
  • 33
  • 33
  • 24
  • 18
  • 15
  • 11
  • 9
  • 7
  • 3
  • 2
  • 2
  • 1
Western Blotting (WB), Immunofluorescence (IF)
  • Bindungsspezifität

    • 29
    • 19
    • 16
    • 13
    • 6
    • 5
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-300

    Sequenz

    MSTTVNVDSL AEYEKSQIKR ALELGTVMTV FSFRKSTPER RTVQVIMETR QVAWSKTADK IEGFLDIMEI KEIRPGKNSK DFERAKAVRQ KEDCCFTILY GTQFVLSTLS LAADSKEDAV NWLSGLKILH QEAMNASTPT IIESWLRKQI YSVDQTRRNS ISLRELKTIL PLINFKVSSA KFLKDKFVEI GAHKDELSFE QFHLFYKKLM FEQQKSILDE FKKDSSVFIL GNTDRPDASA VYLHDFQRFL IHEQQEHWAQ DLNKVRERMT KFIDDTMRET AEPFLFVDEF LTYLFSRENS

    Kreuzreaktivität

    Human, Maus

    Produktmerkmale

    Polyclonal Antibodies

    Immunogen

    Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human PLC gamma 2 (PLC gamma 2 (PLCG2)) (NP_002652.2).

    Isotyp

    IgG
  • Applikationshinweise

    WB,1:500 - 1:2000,IF,1:20 - 1:100

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Buffer

    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Handhabung

    Avoid freeze / thaw cycles

    Lagerung

    -20 °C

    Informationen zur Lagerung

    Store at -20°C. Avoid freeze / thaw cycles.
  • Target

    Phospholipase C gamma 2 (PLCG2)

    Andere Bezeichnung

    PLCG2

    Hintergrund

    The protein encoded by this gene is a transmembrane signaling enzyme that catalyzes the conversion of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate to 1D-myo-inositol 1,4,5-trisphosphate (IP3) and diacylglycerol (DAG) using calcium as a cofactor. IP3 and DAG are second messenger molecules important for transmitting signals from growth factor receptors and immune system receptors across the cell membrane. Mutations in this gene have been found in autoinflammation, antibody deficiency, and immune dysregulation syndrome and familial cold autoinflammatory syndrome 3.,PLCG2,APLAID,FCAS3,PLC-IV,PLC-gamma-2,Cancer,Signal Transduction,ErbB-HER Signaling Pathway,MAPK-Erk Signaling Pathway,Cell Biology & Developmental Biology,Cytoskeleton,Actins,Endocrine & Metabolism,Lipid Metabolism,Hydrolysis,Immunology & Inflammation,B Cell Receptor Signaling Pathway,Cardiovascular,Angiogenesis,Lipids,PLCG2

    Molekulargewicht

    147 kDa

    Gen-ID

    5336

    UniProt

    P16885

    Pathways

    RTK Signalweg, WNT Signalweg, Fc-epsilon Rezeptor Signalübertragung, Inositol Metabolic Process, Myometrial Relaxation and Contraction, Toll-Like Receptors Cascades, VEGF Signaling, BCR Signaling
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