MAPK10 Antikörper (AA 175-464)

Produktnummer ABIN3022948

Der Kaninchen Polyklonal Anti-MAPK10-Antikörper wurde für WB validiert. Er ist geeignet, MAPK10 in Proben von Human zu detektieren.

Kurzübersicht für MAPK10 Antikörper (AA 175-464) (ABIN3022948)

Target: MAPK10 (Mitogen-Activated Protein Kinase 10 (MAPK10))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MAPK10 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-MAPK10 Antikörper

Bindungsspezifität: AA 175-464

Sequenz: CGIKHLHSAG IIHRDLKPSN IVVKSDCTLK ILDFGLARTA GTSFMMTPYV VTRYYRAPEV ILGMGYKENV DIWSVGCIMG EMVRHKILFP GRDYIDQWNK VIEQLGTPCP EFMKKLQPTV RNYVENRPKY AGLTFPKLFP DSLFPADSEH NKLKASQARD LLSKMLVIDP AKRISVDDAL QHPYINVWYD PAEVEAPPPQ IYDKQLDERE HTIEEWKELI YKEVMNSEEK TKNGVVKGQP SPSGAAVNSS ESLPPSSSVN DISSMSTDQT LASDTDSSLE ASAGPLGCCR

Kreuzreaktivität: Maus

Produktmerkmale: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 175-464 of human JNK3 (NP_620448.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid freeze / thaw cycles

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu MAPK10

Target: MAPK10 (Mitogen-Activated Protein Kinase 10 (MAPK10))

Andere Bezeichnung: MAPK10

Hintergrund: The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as integration points for multiple biochemical signals and are involved in a wide variety of cellular processes, such as proliferation, differentiation, transcription regulation and development. This kinase is specifically expressed in a subset of neurons in the nervous system and is activated by threonine and tyrosine phosphorylation. Targeted deletion of this gene in mice suggests that it may have a role in stress-induced neuronal apoptosis. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. A recent study provided evidence for translational readthrough in this gene and expression of an additional C-terminally extended isoform via the use of an alternative in-frame translation termination codon.,JNK3,JNK3A,PRKM10,SAPK1b,p493F12,p54bSAPK,MAPK10,Cancer,Signal Transduction,G protein signaling,G2/M DNA Damage Checkpoint,Kinase,Serine/threonine kinases,ErbB-HER Signaling Pathway,MAPK-JNK Signaling Pathway,Cell Biology & Developmental Biology,Apoptosis,Mitochondrial Control of Apoptosis,Inhibition of Apoptosis,Death Receptor Signaling Pathway,TGF-b-Smad Signaling Pathway,Endocrine & Metabolism,Insulin Receptor Signaling Pathway,Immunology & Inflammation,B Cell Receptor Signaling Pathway,T Cell Receptor Signaling Pathway,NF-kB Signaling Pathway,Toll-like Receptor Signaling Pathway,Neuroscience,Neurodegenerative Diseases,Dopamine Signaling in Parkinson's Disease,MAPK10

Molekulargewicht: 48 kDa/52 kDa

Gen-ID: 5602

UniProt: P53779

Pathways: MAPK Signalweg, WNT Signalweg, TLR Signalweg, Fc-epsilon Rezeptor Signalübertragung, Activation of Innate immune Response, Hepatitis C, Toll-Like Receptors Cascades