Insulin Antikörper (C-Term)
Kurzübersicht für Insulin Antikörper (C-Term) (ABIN295071)
Target
Alle Insulin (INS) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Bindungsspezifität
- C-Term
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Spezifität
- C-terminal pentapeptide of insulin beta-chain. MAbs 7F8, D4B8, 3A6 and 8E2 react with different antigenic determinants. Kass MAb 7F8 is 7.5 x 109 M-1 Kass MAb D4B8 is 1.5 x 108 M-1 Kass MAb 3A6 is 8.0 x 108 M-1 Kass MAb 8E2 is 6.0 x 108 M-1 Kass MAb C7C9 is 1.0 x 109 M-1 Kass MAb 7F5 is 1.0 x 109 M-1 These antibodies cross-react with human proinsulin, bovine insulin (30 % ) and porcine insulin. No cross-reaction with free C-peptide.
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Aufreinigung
- Protein A purified
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Immunogen
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Purified human insulin.
Type of Immunogen: Purified protein -
Isotyp
- IgG1
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Kommentare
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Target Species of Antibody: Human
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- Lot specific
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Buffer
- PBS, pH 7.4, 0.1 % sodium azide.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- avoid freezing
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Lagerung
- 4 °C
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Informationen zur Lagerung
- 4°C, avoid freezing.
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- Insulin (INS)
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Andere Bezeichnung
- Insulin
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Hintergrund
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Name/Gene ID: INS
Family: Hormone
Synonyms: INS, IRDN, IDDM2, Preproinsulin, ILPR, Insulin, MODY10, Proinsulin -
Gen-ID
- 3630
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UniProt
- P01308
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Pathways
- NF-kappaB Signalweg, RTK Signalweg, Positive Regulation of Peptide Hormone Secretion, Peptide Hormone Metabolism, Hormone Activity, Carbohydrate Homeostasis, ER-Nucleus Signaling, Regulation of Carbohydrate Metabolic Process, Feeding Behaviour, Autophagie, Negative Regulation of intrinsic apoptotic Signaling, Brown Fat Cell Differentiation, Positive Regulation of fat Cell Differentiation
Target
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