Insulin Antikörper
Kurzübersicht für Insulin Antikörper (ABIN294749)
Target
Alle Insulin (INS) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Spezifität
- The site of connection of C-peptide and C-end of B-chain of proinsulin molecule. MAbs 1D6 and 1D3 react with different epitopes on human proinsulin molecule, both of each are generated by the interactions between insulin and C-peptide parts of prohormone. Kd MAb 3A1 is 1.1 x 10-8 M. Kd MAb 1G4 is 2.6 x 10-7 M. Kd MAb 1D6 and 1D3 is >3 x 10-8 M. Kd MAb 7D6 is >5 x 10-8 M. MAbs 3A1, 1G4, 1D6, 1D3 and 7D6 do not cross-react with human, bovine and porcine insulin, bovine and porcine proinsulin, and human C-peptide.
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Aufreinigung
- Protein A purified
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Immunogen
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Purified human proinsulin.
Type of Immunogen: Purified protein -
Isotyp
- IgG1
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anti-Insulin (INS) (AA 1-110) antibody
INS Reaktivität: Human IHC, WB, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Insulin (INS) (AA 46-59) antibodyINS Reaktivität: Maus, Ratte WB, ELISA, IHC (p), FACS, IF (p), IF (cc), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
anti-Insulin (INS) antibodyINS Reaktivität: Human IHC, WB, IF Wirt: Kaninchen Monoclonal unconjugated
anti-Insulin (INS) (AA 90-110) antibodyINS Reaktivität: Maus IHC, WB, IP, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Insulin (INS) (AA 25-110) antibodyINS Reaktivität: Ratte IHC, WB, IP, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Insulin (INS) antibodyINS Reaktivität: Human, Maus, Schwein, Rind (Kuh), Ratte, Kaninchen, Meerschweinchen, Hund, Affe, Cat, Huhn, Esel, Ziege, Hamster, Pferd, Schaf, Avian WB, IHC (p), IHC (fro) Wirt: Ziege Polyclonal unconjugated
anti-Insulin (INS) (AA 25-110) antibodyINS Reaktivität: Human IHC, WB, IP, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Insulin (INS) antibodyINS Reaktivität: Human IHC Wirt: Kaninchen Monoclonal HMV308 unconjugated Recombinant Antibody
anti-Insulin (INS) (AA 25-54) antibodyINS Reaktivität: Rind (Kuh) IHC, WB, IP, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Insulin (INS) (AA 25-110) antibodyINS Reaktivität: Human IHC, WB, IP, ICC Wirt: Maus Monoclonal C1 unconjugated
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Kommentare
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Target Species of Antibody: Human
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- Lot specific
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Buffer
- PBS, pH 7.4, 0.1 % sodium azide.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- avoid freezing
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Lagerung
- 4 °C
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Informationen zur Lagerung
- 4°C, avoid freezing.
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- Insulin (INS)
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Andere Bezeichnung
- Insulin
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Hintergrund
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Name/Gene ID: INS
Family: Hormone
Synonyms: INS, IRDN, IDDM2, Preproinsulin, ILPR, Insulin, MODY10, Proinsulin -
Gen-ID
- 3630
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UniProt
- P01308
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Pathways
- NF-kappaB Signalweg, RTK Signalweg, Positive Regulation of Peptide Hormone Secretion, Peptide Hormone Metabolism, Hormone Activity, Carbohydrate Homeostasis, ER-Nucleus Signaling, Regulation of Carbohydrate Metabolic Process, Feeding Behaviour, Autophagie, Negative Regulation of intrinsic apoptotic Signaling, Brown Fat Cell Differentiation, Positive Regulation of fat Cell Differentiation
Target
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