IFNB1 Antikörper

Produktnummer ABIN289463

Der Ziege Polyklonal Anti-IFNB1-Antikörper wurde für WB, ELISA und Neut validiert. Er ist geeignet, IFNB1 in Proben von Human zu detektieren.

Kurzübersicht für IFNB1 Antikörper (ABIN289463)

Target: IFNB1 (Interferon, beta 1, Fibroblast (IFNB1))

Reaktivität: Human

Wirt: Ziege

Klonalität: Polyklonal

Konjugat: Dieser IFNB1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Neutralization (Neut)

Produktdetails anti-IFNB1 Antikörper

Produktmerkmale: Affinity purified Goat polyclonal IFN beta antibody
Bioactivity: The exact concentration of antibody required to neutralize human interferon beta activity is dependent on the cytokine concentration, cell type, growth conditions and type of activity studied. The Neutralization Dose50 (ND50) for this antibody is defined as that concentration of antibody required to yield one-half maximal inhibition of the cytokine activity on a responsive cell line, when that cytokine is present at a concentration just high enough to elicit a maximum response. The ND50 for this antibody on human (HeLa/EMCV) cells is approx. 0.05- 0.2 µg/mL in the presence of 10ng/mL of human interferon beta, based on the anti-viral assay. The specific conditions are described in the figure legends.

Aufreinigung: Purified

Immunogen: IFN beta antibody was raised in goat using human interferon beta as the immunogen.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal conditions should be determined byt he investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Reconstitute in sterile PBS.

Konzentration: Lot specific

Buffer: Lyophilized from PBS with 5 % trehalose.

Handhabung: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot and store at -20 °C.

Details zu IFNB1

Target: IFNB1 (Interferon, beta 1, Fibroblast (IFNB1))

Andere Bezeichnung: IFN beta

Hintergrund: Interferons (IFNs) are proteins made and released by lymphocytes in response to the presence of pathogens-such as viruses, bacteria, or parasites-or tumor cells. They allow communication between cells to trigger the protective defenses of the immune system that eradicate pathogens or tumors.

Pathways: JAK-STAT Signalweg, T-Zell Rezeptor Signalweg, TLR Signalweg, Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response, Positive Regulation of Endopeptidase Activity, Hepatitis C, Autophagie, Inflammasome