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Bcl-2 Antikörper

BCL2 Reaktivität: Human WB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN2854283
  • Target Alle Bcl-2 (BCL2) Antikörper anzeigen
    Bcl-2 (BCL2) (B-Cell CLL/lymphoma 2 (BCL2))
    Reaktivität
    • 413
    • 172
    • 168
    • 34
    • 23
    • 22
    • 15
    • 9
    • 6
    • 5
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 324
    • 123
    • 4
    • 2
    • 1
    • 1
    • 1
    Kaninchen
    Klonalität
    • 320
    • 135
    Polyklonal
    Konjugat
    • 202
    • 29
    • 27
    • 22
    • 20
    • 12
    • 8
    • 8
    • 8
    • 8
    • 8
    • 8
    • 8
    • 8
    • 8
    • 8
    • 8
    • 8
    • 7
    • 5
    • 5
    • 5
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser Bcl-2 Antikörper ist unkonjugiert
    Applikation
    • 339
    • 185
    • 142
    • 110
    • 95
    • 92
    • 80
    • 64
    • 54
    • 30
    • 24
    • 24
    • 18
    • 8
    • 8
    • 8
    • 5
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Kreuzreaktivität
    Human
    Produktmerkmale
    Rabbit Polyclonal antibody to BCL2 (apoptosis regulator Bcl-2)
    Bcl-2 antibody
    Aufreinigung
    Purified by antigen-affinity chromatography.
    Immunogen
    Recombinant protein encompassing a sequence within the center region of human Bcl-2. The exact sequence is proprietary.
    Isotyp
    IgG
    Top Product
    Discover our top product BCL2 Primärantikörper
  • Applikationshinweise
    WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
    Kommentare

    Positive Control: BCL2-transfected 293T

    Validation: Orthogonal, Overexpression

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/mL
    Buffer
    1XPBS ( pH 7), 20 % Glycerol, 0.01 % Thimerosal
    Konservierungsmittel
    Thimerosal (Merthiolate)
    Vorsichtsmaßnahmen
    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Target
    Bcl-2 (BCL2) (B-Cell CLL/lymphoma 2 (BCL2))
    Andere Bezeichnung
    BCL2 apoptosis regulator (BCL2 Produkte)
    Hintergrund
    This gene encodes an integral outer mitochondrial membrane protein that blocks the apoptotic death of some cells such as lymphocytes. Constitutive expression of BCL2, such as in the case of translocation of BCL2 to Ig heavy chain locus, is thought to be the cause of follicular lymphoma. Two transcript variants, produced by alternate splicing, differ in their C-terminal ends.

    Cellular Localization: Mitochondrion outer membrane , Nucleus membrane , Endoplasmic reticulum membrane
    Molekulargewicht
    26 kDa
    Gen-ID
    596
    UniProt
    P10415
    Pathways
    MAPK Signalweg, PI3K-Akt Signalweg, Apoptose, Caspase Kaskade in der Apoptose, Regulation of Muscle Cell Differentiation, Cell-Cell Junction Organization, Skeletal Muscle Fiber Development, Autophagie, Smooth Muscle Cell Migration, Negative Regulation of intrinsic apoptotic Signaling
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