GSK3 beta Antikörper (N-Term)
Kurzübersicht für GSK3 beta Antikörper (N-Term) (ABIN2798780)
Target
Alle GSK3 beta (GSK3b) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
-
-
Bindungsspezifität
- AA 30-59, N-Term
-
Verwendungszweck
- Rabbit Anti-Mouse Mouse Gsk3b (N-term) Antibody
-
Immunogen
- This Mouse Gsk3b antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 30-59 amino acids from the N-terminal region of mouse Gsk3b.
-
Isotyp
- Ig Fraction
-
-
-
-
Applikationshinweise
-
Western Blot, Immunohistochemistry
Recommended Dilutions
WB: 1:1000, IHC: 1:10-50Mouse Gsk3b Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated. -
Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
-
-
Format
- Liquid
-
Konzentration
- 0.5 mg/mL
-
Lagerung
- 4 °C,-20 °C
-
Informationen zur Lagerung
- 2-8°C (short-term), -20°C (long-term)
-
-
- GSK3 beta (GSK3b) (Glycogen Synthase Kinase 3 beta (GSK3b))
-
Andere Bezeichnung
- Gsk3b
-
Hintergrund
-
Target Description: Participates in the Wnt signaling pathway. Implicated in the hormonal control of several regulatory proteins including glycogen synthase, MYB and the transcription factor JUN. Phosphorylates JUN at sites proximal to its DNA-binding domain, thereby reducing its affinity for DNA. May phosphorylate MUC1 and decrease the interaction of MUC1 with CTNNB1/beta-catenin. Phosphorylates CTNNB1/beta-catenin. Phosphorylates SNAI1 (By similarity).
Gene Symbol: Gsk3b
-
Molekulargewicht
- 46710 Da
-
Gen-ID
- 56637
-
UniProt
- Q9WV60
-
Pathways
- WNT Signalweg, Hedgehog Signalweg, Fc-epsilon Rezeptor Signalübertragung, Cellular Glucan Metabolic Process, ER-Nucleus Signaling, Regulation of Carbohydrate Metabolic Process, Hepatitis C, Autophagie, BCR Signaling, Warburg Effekt
Target
-