GTPase NRas Antikörper (C-Term)
Kurzübersicht für GTPase NRas Antikörper (C-Term) (ABIN2793206)
Target
Alle GTPase NRas (NRAS) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 147-179, C-Term
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Verwendungszweck
- Rabbit Anti-Human NRAS (C-term) Antibody
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Immunogen
- This NRAS antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 147-179 amino acids from the C-terminal region of human NRAS.
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Isotyp
- Ig Fraction
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Applikationshinweise
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Western Blot, Immunohistochemistry, Flow Cytometry
Recommended Dilutions
WB: 1:1000, IHC: 1:10-50, FC: 1:10-50NRAS Antibody (C-term) .FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. -
Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 2.0 mg/mL
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- 2-8°C (short-term), -20°C (long-term)
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- GTPase NRas (NRAS)
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Andere Bezeichnung
- NRAS
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Hintergrund
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Target Description: NRAS is a membrane protein that shuttles between the Golgi apparatus and the plasma membrane. This shuttling is regulated through palmitoylation and depalmitoylation by the ZDHHC9-GOLGA7 complex. This protein, which has intrinsic GTPase activity, is activated to a GTP-bound form by a GTPase activating protein and inactivated to a GDP-bound form by a guanine nucleotide-exchange factor. Defects in the gene encoding this protein are a cause of juvenile myelomonocytic leukemia (JMML).
Gene Symbol: NRAS
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Molekulargewicht
- 21229 Da
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Gen-ID
- 4893
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UniProt
- P01111
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Pathways
- p53 Signalweg, MAPK Signalweg, RTK Signalweg, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Hepatitis C, Regulation of long-term Neuronal Synaptic Plasticity, VEGF Signaling
Target
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