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p53 Antikörper (C-Term)

Name: p53 Antikörper (C-Term)
SKU: ABIN2792141
Price: 457.44 EUR
Availability: InStock

TP53 Reaktivität: Human, Ratte, Pferd WB, IHC Wirt: Kaninchen Polyclonal unconjugated

WB Suggested Anti-TP53 Antibody Titration: 0.

Rabbit Anti-TP53 antibody Catalog Number: AVARP02055 Paraffin Embedded Tissue: Human Lung cell Cellular Data: bronchiole epithelium of renal tubule Antibody Concentration: 4.

IHC

2 Abbildungen

Produktnummer ABIN2792141

Datenblatt (PDF)

Target Alle p53 (TP53) Antikörper anzeigen

p53 (TP53) (Tumor Protein P53 (TP53))
Bindungsspezifität
50

40

40

39

32

30

27

25

24

23

23

20

20

19

18

18

16

16

14

12

10

9

9

9

9

9

8

7

7

7

7

7

6

6

6

5

5

5

5

4

4

4

3

3

3

3

3

3

3

3
C-Term
Reaktivität
893

272

222

113

48

35

33

19

10

8

7

6

4

4

3

3

2

2

2

2

1

1

1

1

1
Human, Ratte, Pferd
Wirt
669

239

6

2

1

1
Kaninchen
Passende Sekundärantikörper
Klonalität
610

307

1
Polyklonal
Konjugat
510

49

40

26

25

25

24

24

23

22

22

13

13

13

13

13

13

5

5

5

5

5

5

2

2

2

2

2

2

2

1

1

1

1

1

1
Dieser p53 Antikörper ist unkonjugiert
Applikation
717

336

257

216

210

151

129

124

119

66

61

35

20

17

13

12

12

10

9

8

6

4

3

3

2

2

2

2

1

1

1

1

1
Western Blotting (WB), Immunohistochemistry (IHC)

Sequenz

RELNEALELK DAQAGKEPGG SRAHSSHLKS KKGQSTSRHK KLMFKTEGPD

Homologie

Horse: 93%, Human: 100%, Rat: 92%

Produktmerkmale

This is a rabbit polyclonal antibody against TP53. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung

Protein A purified

Immunogen

The immunogen is a synthetic peptide directed towards the C terminal region of human TP53

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Applikationshinweise

Optimal working dilutions should be determined experimentally by the investigator.

Kommentare

Antigen size: 393 AA

Beschränkungen

Nur für Forschungszwecke einsetzbar
Format

Liquid

Konzentration

Lot specific

Buffer

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel

Sodium azide

Vorsichtsmaßnahmen

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung

Avoid repeated freeze-thaw cycles.

Lagerung

-20 °C

Informationen zur Lagerung

For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Target

p53 (TP53) (Tumor Protein P53 (TP53))

Andere Bezeichnung

TP53 (TP53 Produkte)

Synonyme

BCC7 antikoerper, LFS1 antikoerper, P53 antikoerper, TRP53 antikoerper, p53 antikoerper, Trp53 antikoerper, brp53 antikoerper, drp53 antikoerper, etID22686.5 antikoerper, fb40d06 antikoerper, wu:fb40d06 antikoerper, zgc:111919 antikoerper, Tp53 antikoerper, bbl antikoerper, bfy antikoerper, bhy antikoerper, p44 antikoerper, tp53 antikoerper, Xp53 antikoerper, TP53 antikoerper, tumor protein p53 antikoerper, cellular tumor antigen p53 antikoerper, transformation related protein 53 antikoerper, tumor protein p53 L homeolog antikoerper, TP53 antikoerper, CpipJ_CPIJ002758 antikoerper, Tp53 antikoerper, tp53 antikoerper, Trp53 antikoerper, tp53.L antikoerper

Hintergrund

TP53 acts as a tumor suppressor in many tumor types, induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process.
Alias Symbols: P53, LFS1, TRP53
Protein Size: 393

Molekulargewicht

44 kDa

Gen-ID

7157

NCBI Accession

NM_000546, NP_000537

UniProt

P04637

Pathways

p53 Signalweg, MAPK Signalweg, PI3K-Akt Signalweg, Apoptose, AMPK Signaling, Chromatin Binding, ER-Nucleus Signaling, Positive Regulation of Endopeptidase Activity, Hepatitis C, Protein targeting to Nucleus, Autophagie, Warburg Effekt