RIPK1 Antikörper (Middle Region)

Produktnummer ABIN2792131

Der Kaninchen Polyklonal anti-RIPK1 Antikörper wird verwendet zum Nachweis von RIPK1 in Proben von Human, Hund, Rind (Kuh) und Pferd. Er wurde validiert für WB.

Kurzübersicht für RIPK1 Antikörper (Middle Region) (ABIN2792131)

Target: RIPK1 (Receptor (TNFRSF)-Interacting serine-threonine Kinase 1 (RIPK1))

Reaktivität: Human, Hund, Rind (Kuh), Pferd

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RIPK1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-RIPK1 Antikörper

Bindungsspezifität: Middle Region

Verwendungszweck: RIPK1 Antibody - middle region

Sequenz: RRRRVSHDPF AQQRPYENFQ NTEGKGTAYS SAASHGNAVH QPSGLTSQPQ

Homologie: Cow: 100%, Dog: 91%, Horse: 83%, Human: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against RIPK1. It was validated on Western Blot using a cell lysate as a positive control.

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human RIPK1

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu RIPK1

Target: RIPK1 (Receptor (TNFRSF)-Interacting serine-threonine Kinase 1 (RIPK1))

Andere Bezeichnung: RIPK1

Hintergrund:

Background Information: FAK overexpression in human tumors provides a survival signal function by binding to RIP and inhibiting its interaction with the death receptor complex.

Gene Name: Receptor (TNFRSF)-interacting serine-threonine kinase 1

Alternative Symbols: RIP, RIP1, AIEFL, IMD57, RIP-1

Protein Name: Receptor-interacting serine/threonine-protein kinase 1

Molekulargewicht: 76kDa

Gen-ID: 8737

NCBI Accession: NP_003795

UniProt: Q13546

Pathways: NF-kappaB Signalweg, Apoptose, Caspase Kaskade in der Apoptose, TLR Signalweg, Activation of Innate immune Response, Inositol Metabolic Process, Positive Regulation of Endopeptidase Activity, Hepatitis C, Protein targeting to Nucleus, Toll-Like Receptors Cascades, Negative Regulation of intrinsic apoptotic Signaling, SARS-CoV-2 Protein Interaktom, Ubiquitin Proteasome Pathway