MAP2K4 Antikörper

Produktnummer ABIN271811

Produktdetails anti-MAP2K4 Antikörper

Target: MAP2K4 (Mitogen-Activated Protein Kinase Kinase 4 (MAP2K4))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MAP2K4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA)

Spezifität: This antibody detects endogenous levels of SEK1/MKK4 protein. (region surrounding Glu74)

Kreuzreaktivität (Details): Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Reinheit: > 95 % pure by SDS-PAGE

Anwendungsinformationen

Applikationshinweise: ELISA: 1: 10000approx. 1: 20000. WB: 1: 500approx. 1: 1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1,0 mg/mL

Buffer: Phosphate buffered saline (PBS), pH 7.2., 0.05 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: DO NOT FREEZE!

Lagerung: 4 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C.

Details zu MAP2K4

Target: MAP2K4 (Mitogen-Activated Protein Kinase Kinase 4 (MAP2K4))

Andere Bezeichnung: MAP2K4 (MAP2K4 Produkte)

Synonyme: JNKK antikoerper, JNKK1 antikoerper, MAPKK4 antikoerper, MEK4 antikoerper, MKK4 antikoerper, PRKMK4 antikoerper, SAPKK-1 antikoerper, SAPKK1 antikoerper, SEK1 antikoerper, SERK1 antikoerper, SKK1 antikoerper, Sek1 antikoerper, Serk1 antikoerper, MKK4A-l antikoerper, map2k4 antikoerper, zgc:136500 antikoerper, jnkk antikoerper, mek4 antikoerper, mkk4 antikoerper, sek1 antikoerper, jnkk1 antikoerper, serk1 antikoerper, xmek2 antikoerper, mapkk4 antikoerper, prkmk4 antikoerper, 142758_at antikoerper, CG9738 antikoerper, CT27508 antikoerper, D-MKK4 antikoerper, DMKK4 antikoerper, Dmel\\CG9738 antikoerper, JNKK2 antikoerper, Mpk4 antikoerper, SEK1/MKK4 antikoerper, dMKK4 antikoerper, dMkk4 antikoerper, hep antikoerper, ARABIDOPSIS THALIANA MITOGEN-ACTIVATED PROTEIN KINASE KINASE 4 antikoerper, ATMEK4 antikoerper, ATMKK4 antikoerper, F19C24.26 antikoerper, F19C24_26 antikoerper, MAP KINASE KINASE 4 antikoerper, mitogen-activated protein kinase kinase 4 antikoerper, MKK4B antikoerper, zgc:194486 antikoerper, mitogen-activated protein kinase kinase 4 antikoerper, mitogen-activated protein kinase kinase 4a antikoerper, MAP kinase kinase 4 antikoerper, mitogen activated protein kinase kinase 4 antikoerper, mitogen-activated protein kinase kinase 4b antikoerper, MAP2K4 antikoerper, Map2k4 antikoerper, map2k4a antikoerper, map2k4 antikoerper, Mkk4 antikoerper, MKK4 antikoerper, map2k4b antikoerper

Hintergrund: The prototype member of this family, designated MAP kinase kinase, or MEK-1, specifically phosphorylates the MAP kinase regulatory threonine and tyrosine residues present in the Thr-Glu-Tyr motif of ERK. A second MEK family member, MEK-2, resembles MEK-1 in its substrate specificity. MEK-3 (or MKK-3) functions to activate p38 MAP kinase, and MEK-4 (also called SEK1 or MKK-4) activates both p38 and JNK MAP kinases. MEK-5 appears to specifically phosphorylate ERK 5, whereas MEK-6 phosphorylates p38 and p38β. MEK-7 (or MKK-7) phosphorylates and activates the JNK signal transduction pathway.Synonyms: Dual specificity mitogen-activated protein kinase kinase 4, JNK-activating kinase 1, MAP Kinase Kinase 4, MAPKK4, MEK-4, MKK4, PRKMK4, SAPK/ERK kinase 1, SERK1, c-Jun N-terminal kinase kinase 1

Molekulargewicht: approx. 44 kDa

Gen-ID: 6416

NCBI Accession: NP_003001

UniProt: P45985

Pathways: MAPK Signalweg, TLR Signalweg, Fc-epsilon Rezeptor Signalübertragung, Activation of Innate immune Response, Toll-Like Receptors Cascades, BCR Signaling