IL-1 beta Antikörper

Produktnummer ABIN2689747

Dieses Anti-IL-1 beta-Antikörper ist ein Armenischer Hamster Monoklonal-Antikörper zur Detektion von IL-1 beta in WB, ELISA, IP und Neut. Geeignet für Maus. Dieses Primary Antibody wurde in 2+ Publikationen zitiert.

Kurzübersicht für IL-1 beta Antikörper (ABIN2689747)

Target: IL-1 beta (IL1B) (Interleukin 1, beta (IL1B))

Reaktivität: Maus

Wirt: Armenischer Hamster

Klonalität: Monoklonal

Konjugat: Dieser IL-1 beta Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunoprecipitation (IP), Neutralization (Neut)

Klon: B122

Produktdetails anti-IL-1 beta Antikörper

Marke: BD Pharmingen™

Produktmerkmale: The B122 antibody recognizes the precursor and mature secreted forms of the mouse IL-1β protein. B122 neutralizes the biological activity of mouse IL-1β, but not the biological activities of mouse IL-1α nor human IL-1β. B122 does not recognize mouse IL-2, IL-4, IL-6, IL-10, TNF or IFN-γ. This antibody also recognizes rat IL-1β. The immunogen used to generate the B122 hybridoma was a purified, mature form of the mouse IL-1β protein.

BD Pharmingen™ Purified Hamster Anti-Mouse IL-1β - Purified - Clone B122 - Isotype Armenian Hamster IgG, λ1 - Reactivity Ms - 0.5 mg

Aufreinigung: The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.

Immunogen: Mouse IL-1beta

Isotyp: IgG lambda

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: Aqueous buffered solution containing ≤0.09 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Store undiluted at 4°C.

Referenzen für anti-IL-1 beta Antikörper (ABIN2689747)

Miller, Krasney, Gauvin, Holbrook, Koonz, Abruzzese, Miller, Pagani, Dolle, Ator: "Inhibition of mature IL-1 beta production in murine macrophages and a murine model of inflammation by WIN 67694, an inhibitor of IL-1 beta converting enzyme." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 154, Issue 3, pp. 1331-8, (1995) (PubMed).

Hogquist, Nett, Sheehan, Pendleton, Schreiber, Chaplin: "Generation of monoclonal antibodies to murine IL-1 beta and demonstration of IL-1 in vivo." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 146, Issue 5, pp. 1534-40, (1991) (PubMed).

Details zu IL-1 beta

Target: IL-1 beta (IL1B) (Interleukin 1, beta (IL1B))

Andere Bezeichnung: IL-1beta

Pathways: NF-kappaB Signalweg, Interferon-gamma Pathway, TLR Signalweg, Negative Regulation of Hormone Secretion, Cellular Response to Molecule of Bacterial Origin, Carbohydrate Homeostasis, Glycosaminoglycan Metabolic Process, Myometrial Relaxation and Contraction, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Autophagie, Cancer Immune Checkpoints, Inflammasome