NFKBIA Antikörper (AA 32-291)

Produktnummer ABIN2668625

Dieses Anti-NFKBIA-Antikörper ist ein Maus Monoklonal-Antikörper zur Detektion von NFKBIA in WB. Geeignet für Human und Maus. Dieses Primary Antibody wurde in 6+ Publikationen zitiert.

Kurzübersicht für NFKBIA Antikörper (AA 32-291) (ABIN2668625)

Target: NFKBIA (Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B-Cells Inhibitor, alpha (NFKBIA))

Reaktivität: Human, Maus

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser NFKBIA Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Klon: 6A920

Produktdetails anti-NFKBIA Antikörper

Bindungsspezifität: AA 32-291

Aufreinigung: Affinity Purified

Immunogen: This IkappaBalpha antibody was raised against a recombinant protein corresponding to amino acid residues 32-291 of human IkappaBalpha.

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 μg/μL

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung:

Avoid repeated freeze/thaw cycles and keep on ice when not in storage.

Lagerung: -80 °C

Informationen zur Lagerung: Antibodies in solution can be stored at -80 °C for 2 years.

Haltbarkeit: 6 months

Referenzen für anti-NFKBIA Antikörper (ABIN2668625)

Blaabjerg, Christensen, Matsumoto, van der Meulen, Huising, Billestrup, Vale: "CRFR1 activation protects against cytokine-induced β-cell death." in: Journal of molecular endocrinology, Vol. 53, Issue 3, pp. 417-27, (2014) (PubMed).

Syeda, Grosjean, Houliston, Keogh, Carter, Paleolog, Wheeler-Jones: "Cyclooxygenase-2 induction and prostacyclin release by protease-activated receptors in endothelial cells require cooperation between mitogen-activated protein kinase and NF-kappaB pathways." in: The Journal of biological chemistry, Vol. 281, Issue 17, pp. 11792-804, (2006) (PubMed).

Frobøse, Rønn, Heding, Mendoza, Cohen, Mandrup-Poulsen, Billestrup: "Suppressor of cytokine Signaling-3 inhibits interleukin-1 signaling by targeting the TRAF-6/TAK1 complex." in: Molecular endocrinology (Baltimore, Md.), Vol. 20, Issue 7, pp. 1587-96, (2006) (PubMed).

Jeong, Pise-Masison, Radonovich, Park, Brady: "A novel NF-kappaB pathway involving IKKbeta and p65/RelA Ser-536 phosphorylation results in p53 Inhibition in the absence of NF-kappaB transcriptional activity." in: The Journal of biological chemistry, Vol. 280, Issue 11, pp. 10326-32, (2005) (PubMed).

Larsen, Størling, Darville, Eizirik, Bonny, Billestrup, Mandrup-Poulsen: "Extracellular signal-regulated kinase is essential for interleukin-1-induced and nuclear factor kappaB-mediated gene expression in insulin-producing INS-1E cells." in: Diabetologia, Vol. 48, Issue 12, pp. 2582-90, (2005) (PubMed).

Han, Karabiyikoglu, Kelly, Sobel, Yenari: "Mild hypothermia inhibits nuclear factor-kappaB translocation in experimental stroke." in: Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, Vol. 23, Issue 5, pp. 589-98, (2003) (PubMed).

Details zu NFKBIA

Target: NFKBIA (Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B-Cells Inhibitor, alpha (NFKBIA))

Andere Bezeichnung: IkappaBalpha

Molekulargewicht: 40 kDa

Gen-ID: 4792

Pathways: NF-kappaB Signalweg, T-Zell Rezeptor Signalweg, TLR Signalweg, Fc-epsilon Rezeptor Signalübertragung, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Maintenance of Protein Location, Hepatitis C, Protein targeting to Nucleus, Toll-Like Receptors Cascades, BCR Signaling