IL12 Antikörper
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- Target Alle IL12 Antikörper anzeigen
- IL12 (Interleukin 12 (IL12))
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Reaktivität
- Maus
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Wirt
- Ratte
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Klonalität
- Monoklonal
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Konjugat
- Dieser IL12 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Flow Cytometry (FACS), Functional Studies (Func), Immunohistochemistry (IHC)
- Aufreinigung
- The antibody was purified by affinity chromatography.
- Klon
- C18-2
- Isotyp
- IgG2a kappa
- Top Product
- Discover our top product IL12 Primärantikörper
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anti-Interleukin 12 (IL12) (AA 51-150) antibody
IL12 Reaktivität: Human ELISA, WB, IF (p), IF (cc), IHC (fro), IHC (p) Wirt: Kaninchen Polyclonal unconjugated
anti-Interleukin 12 (IL12) (AA 168-195) antibodyIL12 Reaktivität: Human ELISA, WB, FACS, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-Interleukin 12 (IL12) antibodyIL12 Reaktivität: Maus ELISA, WB, Neut Wirt: Ziege Polyclonal unconjugated
anti-Interleukin 12 (IL12) antibodyIL12 Reaktivität: Human ELISA, WB, Neut Wirt: Ziege Polyclonal unconjugated
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- Applikationshinweise
- Optimal working dilution should be determined by the investigator.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Konzentration
- 0.5 mg/mL
- Buffer
- Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C
- Informationen zur Lagerung
- The antibody solution should be stored undiluted between 2°C and 8°C.
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- Target
- IL12 (Interleukin 12 (IL12))
- Andere Bezeichnung
- IL-12 (IL12 Produkte)
- Hintergrund
- Interleukin 12 (IL-12) is a heterodimeric pleiotropic 70 kD (p70) cytokine consisting of a 40 kD (p40) subunit and a 35 kD (p35) subunit. IL-12 is a potent regulator of cell-mediated immune responses and key mediator of Th1 cell development. Bioactive IL-12 is secreted by activated B lymphocytes, dendritic cells, and macrophages in response to pathogens or upon interaction with activated T cells.IL-12 p70 stimulates cytotoxic T, NK and LAK cell proliferation, andinduces IFN-γ and TNF production in resting and activated T and NK cells.It has been suggested that IL-12 may have therapeutic potential as a vaccine adjuvant that promotes cellular-immunity and as an anti-tumor and anti-viral agent.
- Pathways
- JAK-STAT Signalweg, TLR Signalweg, Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Activated T Cell Proliferation, Cancer Immune Checkpoints, Inflammasome
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