IL-1 beta Antikörper

Produktnummer ABIN191246

Der Maus Monoklonal Anti-IL-1 beta-Antikörper wurde für ELISA und ELISA (Capture) validiert. Er ist geeignet, IL-1 beta in Proben von Human zu detektieren. Es sind 2+ Publikationen verfügbar.

Kurzübersicht für IL-1 beta Antikörper (ABIN191246)

Target: IL-1 beta (IL1B) (Interleukin 1, beta (IL1B))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser IL-1 beta Antikörper ist unkonjugiert

Applikation: ELISA, ELISA (Capture)

Klon: 1E6

Produktdetails anti-IL-1 beta Antikörper

Spezifität: MAbs react with three different determinants on IL-1, β molecule. MAbs do not inhibit the biological activity of IL-1. IgG2a for MAb 6E10 IgG2b for MAb 11E5 IgM for MAb 5C10

Kreuzreaktivität: Human

Aufreinigung: Purified

Isotyp: IgG2b

Anwendungsinformationen

Applikationshinweise: Detection of IL-1, β in two-site immunoassay. We recommend using mixture of MAbs 6E10 and 11E5 for coating and MAb 5C10 for labeling. Detection of IL-1, β in immunohistochemistry.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS, pH 7.4, 0.1 % sodium azide (NaN3) Material safety note: This product is sold as an antibody preparation for research use only. Standard Laboratory Practices should be followed when handling this material. Contains sodium azide (0.1 %) as preservative

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Referenzen für anti-IL-1 beta Antikörper (ABIN191246)

Rikimaru, Awano, Mineoka, Yoshida, Ansai, Takehara: "Relationship between endothelin-1 and interleukin-1beta in inflamed periodontal tissues." in: Biomedical research (Tokyo, Japan), Vol. 30, Issue 6, pp. 349-55, (2010) (PubMed).

Zavialov, Batchikova, Korpela, Petrovskaya, Korobko, Kersley, MacIntyre, Zavyalov: "Secretion of recombinant proteins via the chaperone/usher pathway in Escherichia coli." in: Applied and environmental microbiology, Vol. 67, Issue 4, pp. 1805-14, (2001) (PubMed).

Details zu IL-1 beta

Target: IL-1 beta (IL1B) (Interleukin 1, beta (IL1B))

Andere Bezeichnung: Interleukin-1 beta / IL-1B

Pathways: NF-kappaB Signalweg, Interferon-gamma Pathway, TLR Signalweg, Negative Regulation of Hormone Secretion, Cellular Response to Molecule of Bacterial Origin, Carbohydrate Homeostasis, Glycosaminoglycan Metabolic Process, Myometrial Relaxation and Contraction, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Autophagie, Cancer Immune Checkpoints, Inflammasome