eIF4EBP1 Antikörper

Produktnummer ABIN135297

Dieses Anti-eIF4EBP1-Antikörper ist ein Ratte Monoklonal-Antikörper zur Detektion von eIF4EBP1 in FACS. Geeignet für Maus.

Kurzübersicht für eIF4EBP1 Antikörper (ABIN135297)

Target: eIF4EBP1 (EIF4EBP1) (Eukaryotic Translation Initiation Factor 4E Binding Protein 1 (EIF4EBP1))

Reaktivität: Maus

Wirt: Ratte

Klonalität: Monoklonal

Konjugat: Dieser eIF4EBP1 Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS)

Klon: FG35-4

Produktdetails anti-eIF4EBP1 Antikörper

Spezifität: Mouse BP-1, Mr 140 kDa

Produktmerkmale: Rat Anti-Mouse BP-1-UNLB

Aufreinigung: Purified

Immunogen: Unknown

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise:

• Applications: FC - Quality tested
• Working Dilutions: Flow Cytometry FITC and BIOT conjugates 1 g/106 cells PE conjugate 0.2 g/106 cells For flow cytometry, the suggested use of these reagents is in a final volume of 100 L

Probenmenge: 1 mL

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: 0.5 mg of purified immunoglobulin in 1.0 mL of borate buffered saline,  pH 8.2. No preservatives or amine-containing buffer salts added

Konservierungsmittel: Without preservative

Handhabung: Each reagent is stable for the period shown on the bottle label if stored as directed.

Lagerung: 4 °C

Informationen zur Lagerung: Store at 2-8°C

Details zu eIF4EBP1

Target: eIF4EBP1 (EIF4EBP1) (Eukaryotic Translation Initiation Factor 4E Binding Protein 1 (EIF4EBP1))

Andere Bezeichnung: BP-1

Hintergrund: BP-1, also known as Ly-51/6C3 antigen, is a type II homodimeric transmembrane glycoprotein formed by two disulfide-linked chains of 140 kDa. Originally identified on the surface of pre-B cell lymphomas the cDNA encoding BP-1/Ly-51/6C3 has been cloned and found to represent aminopeptidase A. It is expressed at high levels on bone marrow stromal cell lines which support in vitro B lymphopoiesis and on a wide variety of mouse tissues known to possess aminopeptidase activity. Subsets of normal bone marrow pre-B and B cells express low levels of BP-1/Ly-51/6C3, which is rapidly upregulated on pre-B cells in the presence of IL-7. The BP-1/6C3 marker is commonly used to identify B cells in different stages of development.

Pathways: MAPK Signalweg, PI3K-Akt Signalweg, RTK Signalweg, AMPK Signaling, Regulation of Cell Size, BCR Signaling