Bcl-2 Antikörper (N-Term)
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- Target Alle Bcl-2 (BCL2) Antikörper anzeigen
- Bcl-2 (BCL2) (B-Cell CLL/lymphoma 2 (BCL2))
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Bindungsspezifität
- N-Term
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Reaktivität
- Human, Maus, Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser Bcl-2 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro))
- Spezifität
- Detects a 25 kDa protein, corresponding to the apparent molecular weight of the alpha isoform of Bcl-2 on SDS-PAGE immunoblots.
- Aufreinigung
- Affinity-purified
- Immunogen
- Synthetic peptide corresponding to the N-terminus of human Bcl-2
- Top Product
- Discover our top product BCL2 Primärantikörper
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- Applikationshinweise
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Western blot analysis (0.5-4 μg/mL). Immunoprecipation (4-8 μg/mL). Immunohistochemistry on frozen sections (10-20 μg/mL).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Konzentration
- 0.2 mg/mL
- Buffer
- PBS, pH 7.2, containing 30 % glycerol, 0.5 % BSA, 0.01 % thimerosal
- Konservierungsmittel
- Thimerosal (Merthiolate)
- Vorsichtsmaßnahmen
- This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid Repeated freeze/defrost cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20 °C. For long-term storage, aliquot and freeze at -20 °C to -70 °C.
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- Target
- Bcl-2 (BCL2) (B-Cell CLL/lymphoma 2 (BCL2))
- Andere Bezeichnung
- Bcl-2 (BCL2 Produkte)
- Synonyme
- Bcl-2 antikoerper, PPP1R50 antikoerper, bcl-2 antikoerper, AW986256 antikoerper, C430015F12Rik antikoerper, D630044D05Rik antikoerper, D830018M01Rik antikoerper, BCL-2 antikoerper, Bcl2 antikoerper, BCL2, apoptosis regulator antikoerper, B cell leukemia/lymphoma 2 antikoerper, B-cell CLL/lymphoma 2a antikoerper, B-cell CLL/lymphoma 2 protein antikoerper, BCL2 antikoerper, Bcl2 antikoerper, bcl2a antikoerper, BCL-2 antikoerper
- Hintergrund
- Bcl-2 and its homologs belong to a family of proteins that either promotes or prevent apoptosis. Bcl-2 alpha and beta are the alternatively spliced isoforms of 25 kDa and 22 kDa mitochondrial integral membrane proteins that inhibit apoptosis. Bcl-2 was identified as a gene translocated from chromosome 18 to the immunoglobulin (Ig) heavy chain locus on chromosome 14 in B lymphocytes, a condition that is associated with the onset of human follicular B cell lymphomas. This interchromosomal translocation leads to constitutive expression of Bcl-2, which results in increased survival and expansion of follicular center cell population.Synonyms: Apoptosis regulator Bcl-2, B-Cell CLL/lymphoma 2, BCL2, Bcl-2 alpha
- Gen-ID
- 596
- NCBI Accession
- NP_000624
- UniProt
- P10415
- Pathways
- MAPK Signalweg, PI3K-Akt Signalweg, Apoptose, Caspase Kaskade in der Apoptose, Regulation of Muscle Cell Differentiation, Cell-Cell Junction Organization, Skeletal Muscle Fiber Development, Autophagie, Smooth Muscle Cell Migration, Negative Regulation of intrinsic apoptotic Signaling
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