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AKT1 Antikörper (AA 107-122)
AKT1
Reaktivität: Human, Ratte, Hund
WB, EIA, IHC (fro)
Wirt: Maus
Monoclonal
5G12
unconjugated
Produktdetails anti-AKT1 Antikörper
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Target
Alle AKT1 Antikörper anzeigen
AKT1
(V-Akt Murine Thymoma Viral Oncogene Homolog 1 (AKT1))
Bindungsspezifität
Alle Epitope für AKT1 Antikörper
AA 107-122
Reaktivität
Alle Reaktivitäten für AKT1 Antikörper
Human, Ratte, Hund
Wirt
Alle Wirte für AKT1 Antikörper
Maus
Klonalität
Alle Klonalitäten für AKT1 Antikörper
Monoklonal
Konjugat
Alle Konjugate für AKT1 Antikörper
Dieser AKT1 Antikörper ist unkonjugiert
Applikation
Alle Applikationen für AKT1 Antikörper
Western Blotting (WB), Enzyme Immunoassay (EIA), Immunohistochemistry (Frozen Sections) (IHC (fro))
Spezifität
This antibody specifically recognizes the alpha isoform of PKB (PKBα/Akt1).
Produktmerkmale
Synonyms: Akt-1, RAC-PK-alpha, Protein kinase B, C-AKT, RAC-alpha serine/threonine-protein kinase
Aufreinigung
Subsequent Thiophilic Adsorption and Size Exclusion Chromatography
Bestandteile
incl. positive Control
Immunogen
Synthetic peptide conjugated to KLH. Epitope: aa 107-122
Klon
5G12
Isotyp
IgG1
Top Product
Discover our top product AKT1 Primärantikörper
Alternativen
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Anwendungsinformationen
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Applikationshinweise
Western Blot: 0.5 μg/mL for HRPO/ECL detection. Recommended buffer: Casein/Tween 20 based blocking and blot incubation buffer. Recommended positive control: Cell lysate from untreated Neuro2A cells. The antiboby crossreacts in immunoblot applications with an unknown protein of ca.120 kDa expressed in human tumor cell lines. ELISA: 0.05 μg/mL. Immunohistochemistry. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Handhabung
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Konzentration
0.1 mg/mL
Buffer
PBS containing 0.09 % Sodium Azide, PEG and Sucrose/50 % Glycerol
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
-20 °C
Informationen zur Lagerung
Store the antibody at -20 °C. Avoid repeated freezing and thawing. Shelf life: one year from despatch.
Haltbarkeit
12 months
Details zu AKT1
(ausblenden)
Target
AKT1
(V-Akt Murine Thymoma Viral Oncogene Homolog 1 (AKT1))
Andere Bezeichnung
AKT1 / PKB (AKT1 Produkte )
Synonyme
AKT antikoerper, CWS6 antikoerper, PKB antikoerper, PKB-ALPHA antikoerper, PRKBA antikoerper, RAC antikoerper, RAC-ALPHA antikoerper, Akt antikoerper, Rac antikoerper, PKB/Akt antikoerper, PKBalpha antikoerper, AKT/PKB antikoerper, AKT1 antikoerper, Akt/PKB antikoerper, Akt1 antikoerper, CG4006 antikoerper, D-Akt antikoerper, DAKT1 antikoerper, DAKT1/PKB antikoerper, DAkt antikoerper, DAkt1 antikoerper, DPKB antikoerper, DRAC-PK antikoerper, DRAC-PK66 antikoerper, DRAC-PK85 antikoerper, Dakt antikoerper, Dakt1 antikoerper, Dmel\\CG4006 antikoerper, Dpkb antikoerper, PKB/AKT antikoerper, PKB/dAKT antikoerper, RacPK antikoerper, akt antikoerper, akt1 antikoerper, dAKT antikoerper, dAKT/dPKB antikoerper, dAKT1 antikoerper, dAkt antikoerper, dAkt/PKB antikoerper, dAkt1 antikoerper, dPKB antikoerper, dakt antikoerper, dakt1 antikoerper, l(3)04226 antikoerper, l(3)89Bq antikoerper, p-Akt antikoerper, pAkt antikoerper, ACT-5 antikoerper, akt-1 antikoerper, pkb antikoerper, v-akt antikoerper, v-akt1 antikoerper, xAct antikoerper, ATAKT1 antikoerper, F18A8.2 antikoerper, F18A8_2 antikoerper, K+ transporter 1 antikoerper, POTASSIUM TRANSPORTER antikoerper, AKT serine/threonine kinase 1 antikoerper, thymoma viral proto-oncogene 1 antikoerper, CG4006 gene product from transcript CG4006-RE antikoerper, actin beta antikoerper, v-akt murine thymoma viral oncogene homolog 1 S homeolog antikoerper, v-akt murine thymoma viral oncogene homolog 1 antikoerper, K+ transporter 1 antikoerper, Serine/threonine-protein kinase akt-1 antikoerper, AKT1 antikoerper, Akt1 antikoerper, ACTB antikoerper, akt1.S antikoerper, akt1 antikoerper, KT1 antikoerper, akt-1 antikoerper
Hintergrund
The PKB (RAC/akt) protein kinases are a family of second messenger-regulated serine/threonine kinases. Three mammalian isoforms (alpha, beta, gamma) have been identified so far, the alpha-isoform being the cellular homologue of the v-akt oncogene. Stimulation of cells with growth factors leads to activation of PKB by a phosphoinositide-3-kinase dependent signal transduction pathway.Synonyms: Akt-1, C-AKT, Protein kinase B, RAC-PK-alpha, RAC-alpha serine/threonine-protein kinase
Molekulargewicht
60 kDa
Gen-ID
207
UniProt
P31749
Pathways
PI3K-Akt Signalweg , RTK Signalweg , T-Zell Rezeptor Signalweg , AMPK Signaling , Interferon-gamma Pathway , TLR Signalweg , Fc-epsilon Rezeptor Signalübertragung , EGFR Signaling Pathway , Neurotrophin Signalübertragung , Response to Water Deprivation , Regulation of Actin Filament Polymerization , Carbohydrate Homeostasis , Glycosaminoglycan Metabolic Process , Cellular Glucan Metabolic Process , Regulation of Muscle Cell Differentiation , Cell-Cell Junction Organization , Regulation of Cell Size , Skeletal Muscle Fiber Development , Regulation of Carbohydrate Metabolic Process , Hepatitis C , Protein targeting to Nucleus , CXCR4-mediated Signaling Events , Signaling Events mediated by VEGFR1 and VEGFR2 , Negative Regulation of intrinsic apoptotic Signaling , Thromboxane A2 Receptor Signaling , Signaling of Hepatocyte Growth Factor Receptor , Positive Regulation of fat Cell Differentiation , VEGFR1 Specific Signals , VEGF Signaling , Warburg Effekt
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