IL-1 beta Antikörper

Produktnummer ABIN114529

Dieser Maus Monoklonal Antikörper detektiert spezifisch IL-1 beta in WB und EIA. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für IL-1 beta Antikörper (ABIN114529)

Target: IL-1 beta (IL1B) (Interleukin 1, beta (IL1B))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser IL-1 beta Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA)

Klon: S1H12

Produktdetails anti-IL-1 beta Antikörper

Spezifität: Reactive with natural and recombinant human IL-1β. Does not show any cross reaction with recombinant human IL-1α, recombinant murine IL-1α or IL-1β.

Aufreinigung: Protein G affinity purified

Immunogen: Purified recombinant human IL-1beta

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: ELISA. Western Blot: An antibody concentration of 20-100 ng/mL will allow visualization of 100 ng/lane of human IL-1β.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Rekonstitution: Restore with double distillated water is recommended to adjust the final concentration to 1.00 mg/mL

Buffer: 0.01 M PBS, pH 7.2

Handhabung: Avoid repeated freezing and thawing. Should this product contain a precipitate we recommend microcentrifugation before use.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer.

Details zu IL-1 beta

Target: IL-1 beta (IL1B) (Interleukin 1, beta (IL1B))

Andere Bezeichnung: Interleukin-1 beta / IL-1B

Hintergrund: Interleukin 1 (IL1), originally known as lymphocyte activating factor (LAF), activates T cells and lymphocytes, which then proliferate and secrete interleukin 2. IL1 is primarily released from stimulated macrophages and monocytes, but also is released from several other cell types, and is thought to play a key role in inflammatory and immune responses. The two closely related agents, interleukin1 alpha (IL1 alpha) and interleukin1 beta (IL1 beta) bind to the same cell surface receptor, elicit nearly identical biological responses and share 25 % homology in their amino acid sequence.Synonyms: Catabolin, IL-1 beta, IL1 beta, IL1B, IL1F2

Gen-ID: 3553

NCBI Accession: NP_000567

UniProt: P01584

Pathways: NF-kappaB Signalweg, Interferon-gamma Pathway, TLR Signalweg, Negative Regulation of Hormone Secretion, Cellular Response to Molecule of Bacterial Origin, Carbohydrate Homeostasis, Glycosaminoglycan Metabolic Process, Myometrial Relaxation and Contraction, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Autophagie, Cancer Immune Checkpoints, Inflammasome