Insulin Antikörper

Produktnummer ABIN112182

Der Maus Monoklonal anti-Insulin Antikörper (Klon E6-E5 (7F8)) (ABIN112182) detektiert spezifisch Insulin in EIA und ELISA (Capture). Dieser Antikörper reagiert spezifisch mit Proben aus Human, Schwein und Rind (Kuh).

Kurzübersicht für Insulin Antikörper (ABIN112182)

Target: Insulin (INS)

Reaktivität: Human, Schwein, Rind (Kuh)

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Insulin Antikörper ist unkonjugiert

Applikation: Enzyme Immunoassay (EIA), ELISA (Capture)

Klon: E6-E5 (7F8)

Produktdetails anti-Insulin Antikörper

Spezifität: BM505 recognizes Insulin, a major metabolic hormone produced by B cells of the pancreas.Aff. Const.:8 x 10e9 Me-1

Aufreinigung: Affinity Chromatography on Protein A

Immunogen: Human Insulin.

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: ELISA: BM505 is suitable for use as Coating antibody in a Sandwich ELISA withABIN356107 as the Detection antibody.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: PBS containing 0.09 % Sodium Azide as preservative

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu Insulin

Target: Insulin (INS)

Andere Bezeichnung: Insulin

Hintergrund: Insulin is one of the major regulatory hormones of intermediate metabolism throughout the body. The biological actions of this hormone involve integration of carbohydrate, protein, and lipid metabolism. Insulin enhances membrane transport of glucose, amino acids, and certain ions. It also promotes glycogen storage, formation of triglycerides and synthesis of proteins and nucleic acids. Immunocytochemical investigations have localized insulin in the B cells of pancreatic islets of Langerhans. Deficiency of insulin results in diabetes mellitus, one of the leading causes of morbidity and mortality in the general population. Insulin is also present in tumors of B cell origin such as insulinoma.Synonyms: INS

Gen-ID: 3630

NCBI Accession: NP_000198

UniProt: P01308

Pathways: NF-kappaB Signalweg, RTK Signalweg, Positive Regulation of Peptide Hormone Secretion, Peptide Hormone Metabolism, Hormone Activity, Carbohydrate Homeostasis, ER-Nucleus Signaling, Regulation of Carbohydrate Metabolic Process, Feeding Behaviour, Autophagie, Negative Regulation of intrinsic apoptotic Signaling, Brown Fat Cell Differentiation, Positive Regulation of fat Cell Differentiation