Bcl-2 Antikörper

Produktnummer ABIN1112797

Dieses Maus Monoklonal-Antikörper erkennt spezifisch Bcl-2 in WB, IHC, IHC (p) und ICC. Er zeigt eine Reaktivität gegenüber Maus.

Kurzübersicht für Bcl-2 Antikörper (ABIN1112797)

Target: Bcl-2 (BCL2) (B-Cell CLL/lymphoma 2 (BCL2))

Reaktivität: Maus

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Bcl-2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)

Klon: D24-5

Produktdetails anti-Bcl-2 Antikörper

Immunogen: Recombinant Bcl-2 protein.

Isotyp: IgG2b

Anwendungsinformationen

Applikationshinweise: WB (1:10,000), IHC-P (1:200), ICC (1:500). Other applications have not been tested. The optimal dilutions should be determined by end user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: TBS (pH7.4), 0.5% BSA, 40% Glycerol and 0.05% Sodium Azide.

Konservierungsmittel: Sodium azide, Thimerosal (Merthiolate)

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 4 °C after thawing (1 week). Aliquot and store at -20 °C for long term (at least one year). Avoid repeated freeze and thaw cycles.

Haltbarkeit: 12 months

Details zu Bcl-2

Target: Bcl-2 (BCL2) (B-Cell CLL/lymphoma 2 (BCL2))

Andere Bezeichnung: B-Cell Lymphoma 2, Bcl-2

Hintergrund: Bcl-2 (B-cell lymphoma 2) is the founding member of the Bcl-2 family of apoptosis regulator proteins encoded by the BCL2 gene. 1,2 Bcl-2 is an important regulator of photoreceptor cell death in retinal degenerations. 3 The bcl-2 protooncogene, which protects various cell types from apoptotic cell death, is expressed in the developing and adult nervous system. Bcl-2 may play an important role in survival of neurons both during development and throughout adult life. 4

Pathways: MAPK Signalweg, PI3K-Akt Signalweg, Apoptose, Caspase Kaskade in der Apoptose, Regulation of Muscle Cell Differentiation, Cell-Cell Junction Organization, Skeletal Muscle Fiber Development, Autophagie, Smooth Muscle Cell Migration, Negative Regulation of intrinsic apoptotic Signaling