anti-Meerschweinchen WNT1 Antikörper für Western Blotting

Recommended WNT1 Antibody (geliefert von: Anmelden zum Anzeigen )

Antigen
Wingless-Type MMTV Integration Site Family, Member 1 (WNT1) Antikörper
  • Xint-1
  • Xwnt1
  • int-1
  • int1
  • wnt-1
  • wnt1-a
  • Int-1
  • Wnt-1
  • sw
  • swaying
  • BMND16
  • INT1
  • OI15
  • Int1
  • WNT-1
  • sb:eu647
  • zgc:194464
  • zgc:194478
  • WNT1
  • Wnt family member 1
  • Wnt family member 1 L homeolog
  • wingless-type MMTV integration site family, member 1
  • WNT1
  • wnt1.L
  • Wnt1
  • wnt1
Epitop
Middle Region
15
15
8
6
2
1
1
1
1
1
1
1
Reaktivität
Rind (Kuh), Hund, Meerschweinchen, Pferd, Human, Maus, Kaninchen, Ratte (Rattus), Zebrafisch
114
51
22
11
7
7
7
5
5
3
3
2
2
2
1
1
Wirt
Kaninchen
94
20
Klonalität
Polyklonal
Konjugat
Dieser WNT1 Antikörper ist unkonjugiert
5
1
1
1
1
1
Applikation
Western Blotting (WB)
91
48
33
32
19
17
7
6
2
2
1
1
1
Optionen
Hersteller
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Bilder

Produktnummer ABIN2779465
$ 289.00
Zzgl. Versandkosten $45.00
Relevance Score ABIN Application Konjugat Host Isotype Epitope Hersteller Clonality References Details
3.210425 ABIN2779466 WB Rabbit C-Term Anmelden zum Anzeigen Polyclonal
1 ABIN467727 WB Rabbit AA 180-229 Anmelden zum Anzeigen Polyclonal
1 ABIN1948732 WB Rabbit AA 297-346 Anmelden zum Anzeigen Polyclonal

General

Antigen Wingless-Type MMTV Integration Site Family, Member 1 (WNT1) Antikörper
Epitop Middle Region
(15), (15), (8), (6), (2), (1), (1), (1), (1), (1), (1), (1)
Reaktivität Rind (Kuh), Hund, Meerschweinchen, Pferd, Human, Maus, Kaninchen, Ratte (Rattus), Zebrafisch
(114), (51), (22), (11), (7), (7), (7), (5), (5), (3), (3), (2), (2), (2), (1), (1)
Wirt Kaninchen
(94), (20)
Klonalität
Polyklonal
Konjugat Dieser WNT1 Antikörper ist unkonjugiert
(5), (1), (1), (1), (1), (1)
Applikation Western Blotting (WB)
(91), (48), (33), (32), (19), (17), (7), (6), (2), (2), (1), (1), (1)
Pubmed 1 Publikation vorhanden
Hersteller Anmelden zum Anzeigen

Produktdetails anti-WNT1 Antikörper

Target Details WNT1 Anwendungsinformationen Handhabung Referenzen für anti-WNT1 Antikörper (ABIN2779465) Bilder
Blocking Peptide Zu diesem Produkt passt das Blocking Peptide ABIN986208.
Sequenz FGREFVDSGE KGRDLRFLMN LHNNEAGRTT VFSEMRQECK CHGMSGSCTV
Homologie Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 79%
Produktmerkmale This is a rabbit polyclonal antibody against WNT1. It was validated on Western Blot using a cell lysate as a positive control.
Reinigung Affinity Purified
Immunogen The immunogen is a synthetic peptide directed towards the middle region of human WNT1

Target Details WNT1

Produktdetails anti-WNT1 Antikörper Anwendungsinformationen Handhabung Referenzen für anti-WNT1 Antikörper (ABIN2779465) Bilder zurück nach oben
Antigen
Andere Bezeichnung WNT1 (WNT1 Antibody Abstract)
Hintergrund WNT1 is a member of the WNT gene family. The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. WNT1 is very conserved in evolution, and it is known to be 98 % identical to the mouse Wnt1 protein at the amino acid level. The studies in mouse indicate that the Wnt1 protein functions in the induction of the mesencephalon and cerebellum. WNT1 was originally considered as a candidate gene for Joubert syndrome, an autosomal recessive disorder with cerebellar hypoplasia as a leading feature. However, further studies suggested that the gene mutations might not have a significant role in Joubert syndrome. WNT1 is clustered with another family member, WNT10B, in the chromosome 12q13 region.The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It is very conserved in evolution, and the protein encoded by this gene is known to be 98 % identical to the mouse Wnt1 protein at the amino acid level. The studies in mouse indicate that the Wnt1 protein functions in the induction of the mesencephalon and cerebellum. This gene was originally considered as a candidate gene for Joubert syndrome, an autosomal recessive disorder with cerebellar hypoplasia as a leading feature. However, further studies suggested that the gene mutations might not have a significant role in Joubert syndrome. This gene is clustered with another family member, WNT10B, in the chromosome 12q13 region. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: INT1
Protein Interaction Partner: FZD8, LRP6, POLR2C, ROR2, WIF1, SFRP2, SFRP1, PORCN, WNT3A, LRP5, FZD9, RYK,
Protein Size: 370
Molekulargewicht 38 kDa
Gen-ID 7471
NCBI Accession NM_005430, NP_005421
UniProt P04628
Pathways WNT Signalweg, Dopaminergic Neurogenesis

Anwendungsinformationen

Produktdetails anti-WNT1 Antikörper Target Details WNT1 Handhabung Referenzen für anti-WNT1 Antikörper (ABIN2779465) Bilder zurück nach oben
Applikationshinweise Optimal working dilutions should be determined experimentally by the investigator.
Kommentare

Antigen size: 370 AA

Beschränkungen Nur für Forschungszwecke einsetzbar

Handhabung

Produktdetails anti-WNT1 Antikörper Target Details WNT1 Anwendungsinformationen Referenzen für anti-WNT1 Antikörper (ABIN2779465) Bilder zurück nach oben
Format Liquid
Konzentration Lot specific
Buffer Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Konservierungsmittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung Avoid repeated freeze-thaw cycles.
Lagerung -20 °C
Informationen zur Lagerung For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-WNT1 Antikörper (ABIN2779465)

Produktdetails anti-WNT1 Antikörper Target Details WNT1 Anwendungsinformationen Handhabung Bilder zurück nach oben
Allgemeine Veröffentlichungen

David, Brenner, Stieber, Schwarz, Brunner, Vollmer, Mentele, Müller-Höcker, Kitajima, Lickert, Rupp, Franz: "MesP1 drives vertebrate cardiovascular differentiation through Dkk-1-mediated blockade of Wnt-signalling." in: Nature cell biology, Vol. 10, Issue 3, pp. 338-45, 2008

Bilder

Produktdetails anti-WNT1 Antikörper Target Details WNT1 Anwendungsinformationen Handhabung Referenzen für anti-WNT1 Antikörper (ABIN2779465) zurück nach oben
Bilder des Herstellers
Western Blotting (WB) image for anti-Wingless-Type MMTV Integration Site Family, Member 1 (WNT1) (Middle Region) antibody (ABIN2779465) WB Suggested Anti-WNT1 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: ...
Western Blotting (WB) image for anti-Wingless-Type MMTV Integration Site Family, Member 1 (WNT1) (Middle Region) antibody (ABIN2779465) Sample Type: 1. Molecular Weight
2. Control (20ug)
3. shRNA1-WNT1 H9 hES...