WNT1 Antikörper (AA 251-350)

Produktnummer ABIN733748

Produktdetails anti-WNT1 Antikörper

Target: WNT1 (Wingless-Type MMTV Integration Site Family, Member 1 (WNT1))

Bindungsspezifität: AA 251-350

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser WNT1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Kreuzreaktivität: Human, Maus, Ratte

Homologie: Cow,Horse,Chicken

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Wnt1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Referenzen für anti-WNT1 Antikörper (ABIN733748)

Chen, Chen, Wallace, Chen, Yang, Sung, Chiang, Chen, Chua, Yip, Cheng: "Combined therapy with melatonin and exendin-4 effectively attenuated the deterioration of renal function in rat cardiorenal syndrome." in: American journal of translational research, Vol. 9, Issue 2, pp. 214-229, (2017) (PubMed).

Shan, Lv, Zhao, Liu, Sun, Xi, Xiao, Li: "Wnt/β-catenin pathway is required for epithelial to mesenchymal transition in CXCL12 over expressed breast cancer cells." in: International journal of clinical and experimental pathology, Vol. 8, Issue 10, pp. 12357-67, (2016) (PubMed).

Gao, Yang, Gao, Xu, Niu, Li, Wen: "Salvianolic acid B improves bone marrow-derived mesenchymal stem cell differentiation into alveolar epithelial cells type I via Wnt signaling." in: Molecular medicine reports, Vol. 12, Issue 2, pp. 1971-6, (2015) (PubMed).

Gao, Liu, Chen, Lv, Wu, Mi, Wang: "Comparative study of Hsp27, GSK3?, Wnt1 and PRDX3 in Hirschsprung's disease." in: International journal of experimental pathology, Vol. 95, Issue 3, pp. 229-37, (2014) (PubMed).

Details zu WNT1

Target: WNT1 (Wingless-Type MMTV Integration Site Family, Member 1 (WNT1))

Andere Bezeichnung: Wnt1 (WNT1 Produkte)

Synonyme: Xint-1 antikoerper, Xwnt1 antikoerper, int-1 antikoerper, int1 antikoerper, wnt-1 antikoerper, wnt1-a antikoerper, Int-1 antikoerper, Wnt-1 antikoerper, sw antikoerper, swaying antikoerper, BMND16 antikoerper, INT1 antikoerper, OI15 antikoerper, Int1 antikoerper, WNT-1 antikoerper, sb:eu647 antikoerper, zgc:194464 antikoerper, zgc:194478 antikoerper, WNT1 antikoerper, Wnt family member 1 antikoerper, Wnt family member 1 L homeolog antikoerper, wingless-type MMTV integration site family, member 1 antikoerper, WNT1 antikoerper, wnt1.L antikoerper, Wnt1 antikoerper, wnt1 antikoerper

Hintergrund:

Synonyms: INT1, OI15, BMND16, Proto-oncogene Wnt-1, Proto-oncogene Int-1 homolog, WNT1

Background: Ligand for members of the frizzled family of seven transmembrane receptors. In some developmental processes, is also a ligand for the coreceptor RYK, thus triggering Wnt signaling. Probable developmental protein. May be a signaling molecule important in CNS development. Is likely to signal over only few cell diameters. Has a role in osteoblast function and bone development.

Gen-ID: 7471

UniProt: P04628

Pathways: WNT Signalweg, Dopaminergic Neurogenesis