WNT1 Antikörper

Produktnummer ABIN969458

Produktdetails anti-WNT1 Antikörper

Target: WNT1 (Wingless-Type MMTV Integration Site Family, Member 1 (WNT1))

Reaktivität: Human, Maus

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser WNT1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunocytochemistry (ICC)

Aufreinigung: purified

Immunogen: Purified recombinant fragment of WNT1 expressed in E. coli.

Klon: 10C8

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: ELISA: 1:10000, WB: 1:500 - 1:2000, IHC: 1:200 - 1:1000, ICC: 1:200 - 1:1000, FCM: 1:200 - 1:400

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: 4°C, -20°C for long term storage

Referenzen für anti-WNT1 Antikörper (ABIN969458)

Toffart, Moro-Sibilot, Couraud, Merle, Perol, Girard, Souquet, Mastroianni, Ferretti, Romand, Chatellain, Vesin, Brambilla, Brambilla, Timsit: "Evaluation of RECIST in chemotherapy-treated lung cancer: the Pharmacogenoscan Study." in: BMC cancer, Vol. 14, pp. 989, (2015) (PubMed).

Details zu WNT1

Target: WNT1 (Wingless-Type MMTV Integration Site Family, Member 1 (WNT1))

Andere Bezeichnung: WNT1 (WNT1 Produkte)

Synonyme: Xint-1 antikoerper, Xwnt1 antikoerper, int-1 antikoerper, int1 antikoerper, wnt-1 antikoerper, wnt1-a antikoerper, Int-1 antikoerper, Wnt-1 antikoerper, sw antikoerper, swaying antikoerper, BMND16 antikoerper, INT1 antikoerper, OI15 antikoerper, Int1 antikoerper, WNT-1 antikoerper, sb:eu647 antikoerper, zgc:194464 antikoerper, zgc:194478 antikoerper, WNT1 antikoerper, Wnt family member 1 antikoerper, Wnt family member 1 L homeolog antikoerper, wingless-type MMTV integration site family, member 1 antikoerper, WNT1 antikoerper, wnt1.L antikoerper, Wnt1 antikoerper, wnt1 antikoerper

Hintergrund:

Description: WNT1: wingless-type MMTV integration site family, member 1. The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It is very conserved in evolution, and the protein encoded by this gene is known to be 98 % identical to the mouse Wnt1 protein at the amino acid level. The studies in mouse indicate that the Wnt1 protein functions in the induction of the mesencephalon and cerebellum. This gene was originally considered as a candidate gene for Joubert syndrome, an autosomal recessive disorder with cerebellar hypoplasia as a leading feature. However, further studies suggested that the gene mutations might not have a significant rolein Joubert syndrome. This gene is clustered with another family member, WNT10B, in the chromosome 12q13 region.

Aliases: INT1

Molekulargewicht: 41 kDa

Gen-ID: 7471

HGNC: 7471

Pathways: WNT Signalweg, Dopaminergic Neurogenesis