anti-Maus FZD4 Antikörper für Immunohistochemistry (Paraffin-embedded Sections)

Recommended FZD4 Antibody (geliefert von: Anmelden zum Anzeigen )

Antigen
Frizzled Family Receptor 4 (FZD4) Antikörper
  • CG4626
  • DFz4
  • Dfz4
  • Dm Fz4
  • Dmel\\CG4626
  • Fz4
  • anon-WO0170980.10
  • anon-WO0170980.11
  • fz1
  • zg01
  • CD344
  • EVR1
  • FEVR
  • FZD4S
  • Fz-4
  • FzE4
  • GPCR
  • hFz4
  • frizzled4
  • fz4
  • FZ-4
  • frizzled 4
  • frizzled homolog 4
  • frizzled-4
  • frizzled family receptor 4
  • frizzled homolog 4 (Drosophila)
  • fz4
  • fzd4
  • Tsp_10376
  • FZD4
  • Fzd4
Epitop
AA 190-222
27
14
13
11
10
9
8
4
4
3
3
2
2
2
1
1
1
1
1
Reaktivität
Human, Maus, Ratte (Rattus)
127
76
52
8
7
7
7
6
5
5
5
4
3
2
2
1
Wirt
Kaninchen
80
25
22
8
Klonalität
Polyklonal
Konjugat
Dieser FZD4 Antikörper ist unkonjugiert
8
6
4
4
3
3
3
3
3
3
3
2
2
1
1
1
1
1
1
1
Applikation
Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
73
52
25
14
12
12
11
6
2
1
1
1
Optionen
Hersteller
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Bilder

Produktnummer ABIN1714167
304,36 €
Zzgl. Versandkosten 20,00 € und MWSt
Relevance Score ABIN Application Konjugat Host Isotype Epitope Hersteller Clonality References Details
13.36902 ABIN4312597 IHC (p) Rabbit C-Term Anmelden zum Anzeigen Polyclonal
1 ABIN768861 IHC (p) WB Rabbit IgG C-Term Anmelden zum Anzeigen Polyclonal
1 ABIN1048624 IHC (p) Rabbit C-Term Anmelden zum Anzeigen Polyclonal
1 ABIN1711682 IHC (p) WB HRP Rabbit IgG AA 190-222 Anmelden zum Anzeigen Polyclonal
1 ABIN1700665 IHC (p) WB Biotin Rabbit IgG AA 190-222 Anmelden zum Anzeigen Polyclonal
1 ABIN5556828 IHC (p) Rabbit C-Term Anmelden zum Anzeigen Polyclonal

Ähnliche anti-FZD4 Antikörper

Applikation / Reaktivität Ratte (Rattus) Maus Human
ELISA 16 Antikörper 18 Antikörper 49 Antikörper
Immunofluorescence (IF) 8 Antikörper 8 Antikörper
Immunofluorescence (fixed cells) (IF/ICC) 1 Antikörper 1 Antikörper
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 13 Antikörper 13 Antikörper
Immunohistochemistry (IHC) 5 Antikörper 10 Antikörper
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 9 Antikörper 7 Antikörper
Western Blotting (WB) 24 Antikörper 34 Antikörper
Flow Cytometry (FACS) 22 Antikörper
Immunochromatography (IC) 2 Antikörper
Immunocytochemistry (ICC) 5 Antikörper

General

Antigen Frizzled Family Receptor 4 (FZD4) Antikörper
Epitop AA 190-222
(27), (14), (13), (11), (10), (9), (8), (4), (4), (3), (3), (2), (2), (2), (1), (1), (1), (1), (1)
Reaktivität Human, Maus, Ratte (Rattus)
(127), (76), (52), (8), (7), (7), (7), (6), (5), (5), (5), (4), (3), (2), (2), (1)
Wirt Kaninchen
(80), (25), (22), (8)
Klonalität
Polyklonal
Konjugat Dieser FZD4 Antikörper ist unkonjugiert
(8), (6), (4), (4), (3), (3), (3), (3), (3), (3), (3), (2), (2), (1), (1), (1), (1), (1), (1), (1)
Applikation Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(73), (52), (25), (14), (12), (12), (11), (6), (2), (1), (1), (1)
Hersteller Anmelden zum Anzeigen

Produktdetails anti-FZD4 Antikörper

Target Details FZD4 Anwendungsinformationen Handhabung Bilder
Reinigung Purified by Protein A.
Immunogen KLH conjugated synthetic peptide derived from human Frizzled 4/CD344
Isotyp IgG

Target Details FZD4

Produktdetails anti-FZD4 Antikörper Anwendungsinformationen Handhabung Bilder zurück nach oben
Antigen
Andere Bezeichnung Frizzled 4/CD344 (FZD4 Antibody Abstract)
Hintergrund

Receptor for Wnt proteins. Most of frizzled receptors are coupled to the beta-catenin (CTNNB1) canonical signaling pathway, which leads to the activation of disheveled proteins, inhibition of GSK-3 kinase, nuclear accumulation of beta-catenin (CTNNB1) and activation of Wnt target genes. Plays a critical role in retinal vascularization by acting as a receptor for Wnt proteins and norrin (NDP). In retina, it can be both activated by Wnt protein-binding, but also by a Wnt-independent signaling via binding of norrin (NDP), promoting in both cases beta-catenin (CTNNB1) accumulation and stimulation of LEF/TCF-mediated transcriptional programs. A second signaling pathway involving PKC and calcium fluxes has been seen for some family members, but it is not yet clear if it represents a distinct pathway or if it can be integrated in the canonical pathway, as PKC seems to be required for Wnt-mediated inactivation of GSK-3 kinase. Both pathways seem to involve interactions with G-proteins. May be involved in transduction and intercellular transmission of polarity information during tissue morphogenesis and/or in differentiated tissues.

Subcellular location: Extracellular

Synonyms: Fz4, EVR1, FEVR, Fz-4, FzE4, GPCR, hFz4, CD344, FZD4S, Frizzled-4, FZD4

Gen-ID 8322
UniProt Q9ULV1
Pathways WNT Signalweg, Hormone Transport, Sensory Perception of Sound

Anwendungsinformationen

Produktdetails anti-FZD4 Antikörper Target Details FZD4 Handhabung Bilder zurück nach oben
Applikationshinweise WB 1:100-1000
IHC-P 1:100-500
IF(IHC-P) 1:50-200
Beschränkungen Nur für Forschungszwecke einsetzbar

Handhabung

Produktdetails anti-FZD4 Antikörper Target Details FZD4 Anwendungsinformationen Bilder zurück nach oben
Format Liquid
Konzentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
Konservierungsmittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Lagerung -20 °C
Informationen zur Lagerung Store at -20°C
Haltbarkeit 12 months

Bilder

Produktdetails anti-FZD4 Antikörper Target Details FZD4 Anwendungsinformationen Handhabung zurück nach oben
Bilder des Herstellers
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-FZD4 Antikörper (Frizzled Family Receptor 4) (AA 190-222) (ABIN1714167) Formalin-fixed and paraffin embedded mouse embryo labeled with Anti-Frizzled 4/CD344 ...