anti-Hund VASP Antikörper für Immunoprecipitation

Recommended VASP Antibody (geliefert von: Anmelden zum Anzeigen )

Antigen
Vasodilator-Stimulated phosphoprotein (VASP) Antikörper
  • vasp
  • MGC80889
  • wu:fb23b04
  • wu:fk84g05
  • zgc:110347
  • si:dkey-113g17.1
  • si:ch211-202c21.1
  • DDBDRAFT_0188463
  • DDBDRAFT_0229340
  • DDB_0188463
  • DDB_0229340
  • VASP
  • vasodilator-stimulated phosphoprotein
  • Vasodilator-stimulated phosphoprotein
  • zgc:162320
  • vasp
  • AaeL_AAEL010747
  • CpipJ_CPIJ004706
  • CpipJ_CPIJ004707
  • vasP
  • VASP
  • zgc:162320
  • Vasp
Epitop
AA 248-379
52
24
19
15
12
8
7
6
6
4
3
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reaktivität
Hund, Human
275
146
116
19
16
13
8
7
5
3
2
1
1
Wirt
Maus
226
41
8
Klonalität
Monoklonal
Konjugat
Dieser VASP Antikörper ist unkonjugiert
7
6
3
2
2
2
1
1
1
1
1
1
1
1
1
1
1
Applikation
Immunofluorescence (IF), Immunoprecipitation (IP), Immunohistochemistry (IHC), Western Blotting (WB)
246
118
67
50
48
33
27
18
15
11
5
4
2
1
Optionen
Hersteller
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Hersteller Produkt- Nr.
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Bilder

Produktnummer ABIN967977
Preis und Verfügbarkeit auf Anfrage.
Relevance Score ABIN Application Konjugat Host Isotype Epitope Hersteller Clonality References Details
1 ABIN967976 IF IP IHC WB Mouse IgG1 AA 248-379 Anmelden zum Anzeigen 43-VASP 5
1 ABIN198238 ICC FACS IP ELISA WB Mouse IgG1, kappa AA 236-242, pSer239 Anmelden zum Anzeigen 16C2

General

Antigen Vasodilator-Stimulated phosphoprotein (VASP) Antikörper
Epitop AA 248-379
(52), (24), (19), (15), (12), (8), (7), (6), (6), (4), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reaktivität Hund, Human
(275), (146), (116), (19), (16), (13), (8), (7), (5), (3), (2), (1), (1)
Wirt Maus
(226), (41), (8)
Klonalität (Klon)
Monoklonal   ( )
Konjugat Dieser VASP Antikörper ist unkonjugiert
(7), (6), (3), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Applikation Immunofluorescence (IF), Immunoprecipitation (IP), Immunohistochemistry (IHC), Western Blotting (WB)
(246), (118), (67), (50), (48), (33), (27), (18), (15), (11), (5), (4), (2), (1)
Pubmed 5 Publikationen vorhanden
Hersteller Anmelden zum Anzeigen

Produktdetails anti-VASP Antikörper

Target Details VASP Anwendungsinformationen Handhabung Referenzen für anti-VASP Antikörper (ABIN967977) Bilder
Kreuzreaktivität Hund
Produktmerkmale 1. Since applications vary, each investigator should titrate the reagent to obtain optimal results.
2. Please refer to us for technical protocols.
3. Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.
4. Source of all serum proteins is from USDA inspected abattoirs located in the United States.
Reinigung The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
Immunogen Human VASP aa. 248 - 379
Klon 43-VASP
Isotyp IgG1

Target Details VASP

Produktdetails anti-VASP Antikörper Anwendungsinformationen Handhabung Referenzen für anti-VASP Antikörper (ABIN967977) Bilder zurück nach oben
Antigen
Andere Bezeichnung VASP (VASP Antibody Abstract)
Hintergrund Vasodilator-stimulated phosphoprotein (VASP), a substrate for cAMP- and cGMP-dependent kinases, is associated with actin filaments, focal adhesions, and dynamic membrane regions. VASP is composed of several distinct domains: a central L-proline-rich domain contains a GPPPPP motif as a single copy and as a three-fold tandem repeat, as well as three conserved phosphorylation sites for cyclic nucleotide-dependent protein kinases (Ser157, Ser239, and Thr278). A C-terminal domain contains a repetitive mixed-charge cluster which is predicted to form an alpha-helix. The C-terminal domain appears to be responsible for anchoring at focal adhesion sites. VASP has been shown to be a ligand for profilins. Profilins bind to the poly-L-proline motifs of VASP and it is postulated that these two molecules act in concert to convey signal transduction to actin filament formation.
Molekulargewicht 46 kDa
Forschungsgebiet Signaling, Extracellular Matrix
Pathways T-Zell Rezeptor Signalweg, Regulation of Actin Filament Polymerization, Tube Formation

Anwendungsinformationen

Produktdetails anti-VASP Antikörper Target Details VASP Handhabung Referenzen für anti-VASP Antikörper (ABIN967977) Bilder zurück nach oben
Kommentare

Related Products: ABIN968536

Beschränkungen Nur für Forschungszwecke einsetzbar

Handhabung

Produktdetails anti-VASP Antikörper Target Details VASP Anwendungsinformationen Referenzen für anti-VASP Antikörper (ABIN967977) Bilder zurück nach oben
Format Liquid
Konzentration 250 μg/mL
Buffer Aqueous buffered solution containing BSA, glycerol, and ≤0.09 % sodium azide.
Konservierungsmittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung -20 °C
Informationen zur Lagerung Store undiluted at -20° C.

Referenzen für anti-VASP Antikörper (ABIN967977)

Produktdetails anti-VASP Antikörper Target Details VASP Anwendungsinformationen Handhabung Bilder zurück nach oben
Produkt verwendet in:

DeMali, Barlow, Burridge: "Recruitment of the Arp2/3 complex to vinculin: coupling membrane protrusion to matrix adhesion." in: The Journal of cell biology, Vol. 159, Issue 5, pp. 881-91, 2002

Howe, Hogan, Juliano: "Regulation of vasodilator-stimulated phosphoprotein phosphorylation and interaction with Abl by protein kinase A and cell adhesion." in: The Journal of biological chemistry, Vol. 277, Issue 41, pp. 38121-6, 2002

Lawrence, Pryzwansky: "The vasodilator-stimulated phosphoprotein is regulated by cyclic GMP-dependent protein kinase during neutrophil spreading." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 166, Issue 9, pp. 5550-6, 2001

Haffner, Jarchau, Reinhard, Hoppe, Lohmann, Walter: "Molecular cloning, structural analysis and functional expression of the proline-rich focal adhesion and microfilament-associated protein VASP." in: The EMBO journal, Vol. 14, Issue 1, pp. 19-27, 1995

Reinhard, Giehl, Abel, Haffner, Jarchau, Hoppe, Jockusch, Walter: "The proline-rich focal adhesion and microfilament protein VASP is a ligand for profilins." in: The EMBO journal, Vol. 14, Issue 8, pp. 1583-9, 1995

Bilder

Produktdetails anti-VASP Antikörper Target Details VASP Anwendungsinformationen Handhabung Referenzen für anti-VASP Antikörper (ABIN967977) zurück nach oben
Bilder des Herstellers
Western Blotting (WB) image for anti-Vasodilator-Stimulated phosphoprotein (VASP) (AA 248-379) antibody (ABIN967977) Western blot analysis of VASP on human endothelial cell lysate. Lane 1: 1:500, lane 2...
 image for anti-Vasodilator-Stimulated phosphoprotein (VASP) (AA 248-379) antibody (ABIN967977) Immunoflurorescent staining on Human Endothelial cells.
 image for anti-Vasodilator-Stimulated phosphoprotein (VASP) (AA 248-379) antibody (ABIN967977) anti-Vasodilator-Stimulated phosphoprotein (VASP) (AA 248-379) antibody (Image 3)