anti-Maus CCR5 Antikörper für Neutralization

Recommended CCR5 Antibody (geliefert von: Anmelden zum Anzeigen )

Antigen
C-C Chemokine Receptor Type 5 (CCR5) Antikörper
  • CC-CKR-5
  • CCCKR5
  • CCR-5
  • CD195
  • CKR-5
  • CKR5
  • CMKBR5
  • IDDM22
  • Ckr5
  • Cmkbr5
  • CCR1-L
  • GPCR
  • CCR5
  • AM4-7
  • CCR5-L
  • chemokine (C-C motif) receptor 5 (gene/pseudogene)
  • chemokine (C-C motif) receptor 5
  • chemokine (C-C motif) receptor 2
  • C-C chemokine receptor type 5-like
  • CCR5
  • Ccr5
  • CCR2
  • LOC100399144
Reaktivität
Maus
518
86
72
14
14
3
2
1
1
1
1
1
Wirt
Hamster
271
182
72
15
13
Klonalität
Monoklonal
Konjugat
Dieser CCR5 Antikörper ist konjugiert mit Alexa Fluor 647
47
27
23
23
20
17
15
14
13
13
13
8
6
6
5
5
5
5
4
4
4
4
4
3
3
2
2
2
2
2
2
1
1
1
1
1
1
Applikation
Functional Studies (Func), Neutralization (Neut)
346
210
141
66
64
58
57
33
29
17
14
12
12
8
6
5
4
4
3
2
2
2
2
2
1
1
1
Hersteller
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Produktnummer ABIN2657664
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General

Antigen C-C Chemokine Receptor Type 5 (CCR5) Antikörper
Reaktivität Maus
(518), (86), (72), (14), (14), (3), (2), (1), (1), (1), (1), (1)
Wirt Hamster
(271), (182), (72), (15), (13)
Klonalität (Klon)
Monoklonal   ( )
Konjugat Dieser CCR5 Antikörper ist konjugiert mit Alexa Fluor 647
(47), (27), (23), (23), (20), (17), (15), (14), (13), (13), (13), (8), (6), (6), (5), (5), (5), (5), (4), (4), (4), (4), (4), (3), (3), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1)
Applikation Functional Studies (Func), Neutralization (Neut)
(346), (210), (141), (66), (64), (58), (57), (33), (29), (17), (14), (12), (12), (8), (6), (5), (4), (4), (3), (2), (2), (2), (2), (2), (1), (1), (1)
Pubmed 8 Publikationen vorhanden
Hersteller Anmelden zum Anzeigen

Produktdetails anti-CCR5 Antikörper

Target Details CCR5 Anwendungsinformationen Handhabung Referenzen für anti-CCR5 Antikörper (ABIN2657664) Bilder
Reinigung The antibody was purified by affinity chromatography, and conjugated with Alexa Fluor® 647 under optimal conditions.
Klon HM-CCR5
Isotyp IgG

Target Details CCR5

Produktdetails anti-CCR5 Antikörper Anwendungsinformationen Handhabung Referenzen für anti-CCR5 Antikörper (ABIN2657664) Bilder zurück nach oben
Antigen
Andere Bezeichnung CD195 (CCR5 Antibody Abstract)
Hintergrund CD195 is a 45 kD chemokine receptor also known as CCR5. CD195 is a seven transmembrane-spanning G protein-associated molecule expressed on macrophages, a T cell subset, and in the heart, liver, and spleen. CD195 regulates lymphocyte chemotaxis and transendothelial migration during inflammatory processes. CD195 interacts with several ligands including RANTES, MCP-1, MIP-1α, and MIP-1β.
Pathways Cellular Response to Molecule of Bacterial Origin, cAMP Metabolic Process, Regulation of Cell Size

Anwendungsinformationen

Produktdetails anti-CCR5 Antikörper Target Details CCR5 Handhabung Referenzen für anti-CCR5 Antikörper (ABIN2657664) Bilder zurück nach oben
Applikationshinweise Optimal working dilution should be determined by the investigator.
Beschränkungen Nur für Forschungszwecke einsetzbar

Handhabung

Produktdetails anti-CCR5 Antikörper Target Details CCR5 Anwendungsinformationen Referenzen für anti-CCR5 Antikörper (ABIN2657664) Bilder zurück nach oben
Konzentration 0.5 mg/mL
Buffer Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
Konservierungsmittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung Protect from prolonged exposure to light. Do not freeze.
Lagerung 4 °C
Informationen zur Lagerung The antibody solution should be stored undiluted between 2°C and 8°C

Referenzen für anti-CCR5 Antikörper (ABIN2657664)

Produktdetails anti-CCR5 Antikörper Target Details CCR5 Anwendungsinformationen Handhabung Bilder zurück nach oben
Allgemeine Veröffentlichungen

Sharma, Deshmukh, Zheng, Fu, Ju: "X-linked Foxp3 (Scurfy) mutation dominantly inhibits submandibular gland development and inflammation respectively through adaptive and innate immune mechanisms." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 183, Issue 5, pp. 3212-8, 2009

Kohlmeier, Miller, Smith, Lu, Gerard, Cookenham, Roberts, Woodland: "The chemokine receptor CCR5 plays a key role in the early memory CD8+ T cell response to respiratory virus infections." in: Immunity, Vol. 29, Issue 1, pp. 101-13, 2008

Ishida, Kimura, Kondo, Hayashi, Ueno, Takakura, Matsushima, Mukaida: "Essential roles of the CC chemokine ligand 3-CC chemokine receptor 5 axis in bleomycin-induced pulmonary fibrosis through regulation of macrophage and fibrocyte infiltration." in: The American journal of pathology, Vol. 170, Issue 3, pp. 843-54, 2007

Zeiser, Leveson-Gower, Zambricki, Kambham, Beilhack, Loh, Hou, Negrin: "Differential impact of mammalian target of rapamycin inhibition on CD4+CD25+Foxp3+ regulatory T cells compared with conventional CD4+ T cells." in: Blood, Vol. 111, Issue 1, pp. 453-62, 2007

Mao, Paharkova-Vatchkova, Hardy, Miller, Kovats: "Estrogen selectively promotes the differentiation of dendritic cells with characteristics of Langerhans cells." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 175, Issue 8, pp. 5146-51, 2005

Boring, Gosling, Monteclaro, Lusis, Tsou, Charo et al.: "Molecular cloning and functional expression of murine JE (monocyte chemoattractant protein 1) and murine macrophage inflammatory protein 1alpha receptors: evidence for two closely linked C-C ..." in: The Journal of biological chemistry, Vol. 271, Issue 13, pp. 7551-8, 1996

Meyer, Coyle, Proudfoot, Wells, Power: "Cloning and characterization of a novel murine macrophage inflammatory protein-1 alpha receptor." in: The Journal of biological chemistry, Vol. 271, Issue 24, pp. 14445-51, 1996

Napolitano, Seamon, Leonard: "Identification of cell surface receptors for the Act-2 cytokine." in: The Journal of experimental medicine, Vol. 172, Issue 1, pp. 285-9, 1990

Bilder

Produktdetails anti-CCR5 Antikörper Target Details CCR5 Anwendungsinformationen Handhabung Referenzen für anti-CCR5 Antikörper (ABIN2657664) zurück nach oben
Bilder des Herstellers
Flow Cytometry (FACS) image for anti-C-C Chemokine Receptor Type 5 (CCR5) antibody (Alexa Fluor 647) (ABIN2657664) anti-C-C Chemokine Receptor Type 5 (CCR5) antibody (Alexa Fluor 647)