anti-Human CCR5 Antikörper für Intracellular Flow Cytometry

Recommended CCR5 Antibody (geliefert von: Anmelden zum Anzeigen )

Antigen
C-C Chemokine Receptor Type 5 (CCR5) Antikörper
  • CC-CKR-5
  • CCCKR5
  • CCR-5
  • CD195
  • CKR-5
  • CKR5
  • CMKBR5
  • IDDM22
  • Ckr5
  • Cmkbr5
  • CCR1-L
  • GPCR
  • CCR5
  • AM4-7
  • CCR5-L
  • chemokine (C-C motif) receptor 5 (gene/pseudogene)
  • chemokine (C-C motif) receptor 5
  • chemokine (C-C motif) receptor 2
  • C-C chemokine receptor type 5-like
  • CCR5
  • Ccr5
  • CCR2
  • LOC100399144
Reaktivität
Human
517
87
72
14
14
3
2
1
1
1
1
1
Wirt
Maus
270
182
72
15
14
Klonalität
Monoklonal
Konjugat
Dieser CCR5 Antikörper ist konjugiert mit PE
46
27
24
23
20
17
15
14
13
13
13
8
6
6
5
5
5
5
4
4
4
4
4
3
3
2
2
2
2
2
2
1
1
1
1
1
1
Applikation
Flow Cytometry (FACS), Intracellular Flow Cytometry (ICFC)
345
210
141
66
64
58
57
33
29
18
14
12
12
7
6
5
4
4
3
3
2
2
2
2
1
1
1
Hersteller
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Bilder

Produktnummer ABIN2663124
Preis und Verfügbarkeit auf Anfrage.
Relevance Score ABIN Application Konjugat Host Isotype Epitope Hersteller Clonality References Details
1 ABIN2661375 FACS ICFC FITC Mouse IgG2b kappa Anmelden zum Anzeigen J418F1 1
1 ABIN2661552 ICFC FITC Rat IgG2a kappa Anmelden zum Anzeigen HEK-1-85a 11
1 ABIN2663125 FACS ICFC PE Mouse IgG1 kappa Anmelden zum Anzeigen T21-8 6
1 ABIN2661376 FACS ICFC FITC Mouse IgG2b kappa Anmelden zum Anzeigen J418F1 1

General

Antigen C-C Chemokine Receptor Type 5 (CCR5) Antikörper
Reaktivität Human
(517), (87), (72), (14), (14), (3), (2), (1), (1), (1), (1), (1)
Wirt Maus
(270), (182), (72), (15), (14)
Klonalität (Klon)
Monoklonal   ( )
Konjugat Dieser CCR5 Antikörper ist konjugiert mit PE
(46), (27), (24), (23), (20), (17), (15), (14), (13), (13), (13), (8), (6), (6), (5), (5), (5), (5), (4), (4), (4), (4), (4), (3), (3), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1)
Applikation Flow Cytometry (FACS), Intracellular Flow Cytometry (ICFC)
(345), (210), (141), (66), (64), (58), (57), (33), (29), (18), (14), (12), (12), (7), (6), (5), (4), (4), (3), (3), (2), (2), (2), (2), (1), (1), (1)
Pubmed 6 Publikationen vorhanden
Hersteller Anmelden zum Anzeigen

Produktdetails anti-CCR5 Antikörper

Target Details CCR5 Anwendungsinformationen Handhabung Referenzen für anti-CCR5 Antikörper (ABIN2663124) Bilder
Reinigung The antibody was purified by affinity chromatography, and conjugated with PE under optimal conditions. The solution is free of unconjugated PE and unconjugated antibody.
Klon T21-8
Isotyp IgG1 kappa

Target Details CCR5

Produktdetails anti-CCR5 Antikörper Anwendungsinformationen Handhabung Referenzen für anti-CCR5 Antikörper (ABIN2663124) Bilder zurück nach oben
Antigen
Andere Bezeichnung CD195 (CCR5 Antibody Abstract)
Hintergrund CD195, also known as CCR5, is a 45 kD G protein-coupled seven transmembrane CC-chemokine receptor. It binds to MIP-1α, MIP-1β, and RANTES and is expressed on a subset of T cells and monocytes. CD195 mediates an intracellular signal thought to induce differentiation and proliferation. CCR5 has also been shown to act as a co-receptor for R5 HIV-1 cell entry, modification of CCR5 by sulfation contributes to the efficiency of HIV-1 entry. The T21/8 monoclonal antibody has high affinity to CCR5 N-terminal epitope (Met1-Lys22) and is useful for flow cytometric analysis, immunoprecipitation, immunofluorescence microscopy, and ELISA assay of CCR5 expression.
Pathways Cellular Response to Molecule of Bacterial Origin, cAMP Metabolic Process, Regulation of Cell Size

Anwendungsinformationen

Produktdetails anti-CCR5 Antikörper Target Details CCR5 Handhabung Referenzen für anti-CCR5 Antikörper (ABIN2663124) Bilder zurück nach oben
Applikationshinweise Optimal working dilution should be determined by the investigator.
Beschränkungen Nur für Forschungszwecke einsetzbar

Handhabung

Produktdetails anti-CCR5 Antikörper Target Details CCR5 Anwendungsinformationen Referenzen für anti-CCR5 Antikörper (ABIN2663124) Bilder zurück nach oben
Buffer Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide and 0.2 % (w/v) BSA .
Konservierungsmittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung Protect from prolonged exposure to light. Do not freeze.
Lagerung 4 °C
Informationen zur Lagerung The antibody solution should be stored undiluted between 2°C and 8°C.

Referenzen für anti-CCR5 Antikörper (ABIN2663124)

Produktdetails anti-CCR5 Antikörper Target Details CCR5 Anwendungsinformationen Handhabung Bilder zurück nach oben
Allgemeine Veröffentlichungen

Pollok-Kopp, Schwarze, Baradari, Oppermann: "Analysis of ligand-stimulated CC chemokine receptor 5 (CCR5) phosphorylation in intact cells using phosphosite-specific antibodies." in: The Journal of biological chemistry, Vol. 278, Issue 4, pp. 2190-8, 2003

Huttenrauch, Nitzki, Lin, Höning, Oppermann: "Beta-arrestin binding to CC chemokine receptor 5 requires multiple C-terminal receptor phosphorylation sites and involves a conserved Asp-Arg-Tyr sequence motif." in: The Journal of biological chemistry, Vol. 277, Issue 34, pp. 30769-77, 2002

Combadiere, Ahuja, Tiffany, Murphy: "Cloning and functional expression of CC CKR5, a human monocyte CC chemokine receptor selective for MIP-1(alpha), MIP-1(beta), and RANTES." in: Journal of leukocyte biology, Vol. 60, Issue 1, pp. 147-52, 1996

Deng, Liu, Ellmeier, Choe, Unutmaz, Burkhart, Di Marzio, Marmon, Sutton, Hill, Davis, Peiper, Schall, Littman, Landau: "Identification of a major co-receptor for primary isolates of HIV-1." in: Nature, Vol. 381, Issue 6584, pp. 661-6, 1996

Samson, Labbe, Mollereau, Vassart, Parmentier: "Molecular cloning and functional expression of a new human CC-chemokine receptor gene." in: Biochemistry, Vol. 35, Issue 11, pp. 3362-7, 1996

Raport, Gosling, Schweickart, Gray, Charo: "Molecular cloning and functional characterization of a novel human CC chemokine receptor (CCR5) for RANTES, MIP-1beta, and MIP-1alpha." in: The Journal of biological chemistry, Vol. 271, Issue 29, pp. 17161-6, 1996

Bilder

Produktdetails anti-CCR5 Antikörper Target Details CCR5 Anwendungsinformationen Handhabung Referenzen für anti-CCR5 Antikörper (ABIN2663124) zurück nach oben
Bilder des Herstellers
Flow Cytometry (FACS) image for anti-C-C Chemokine Receptor Type 5 (CCR5) antibody (PE) (ABIN2663124) anti-C-C Chemokine Receptor Type 5 (CCR5) antibody (PE)