anti-Human CCR5 Antikörper für Enzyme Immunoassay

Recommended CCR5 Antibody (geliefert von: Anmelden zum Anzeigen )

Antigen
C-C Chemokine Receptor Type 5 (CCR5) Antikörper
  • CC-CKR-5
  • CCCKR5
  • CCR-5
  • CD195
  • CKR-5
  • CKR5
  • CMKBR5
  • IDDM22
  • Ckr5
  • Cmkbr5
  • CCR1-L
  • GPCR
  • CCR5
  • AM4-7
  • CCR5-L
  • chemokine (C-C motif) receptor 5 (gene/pseudogene)
  • chemokine (C-C motif) receptor 5
  • chemokine (C-C motif) receptor 2
  • C-C chemokine receptor type 5-like
  • CCR5
  • Ccr5
  • CCR2
  • LOC100399144
Epitop
AA 3-30, C-Term
51
35
19
15
13
12
11
10
10
9
8
7
7
6
4
3
3
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
Reaktivität
Human
473
81
65
14
14
3
2
1
1
1
1
1
Wirt
Ziege
227
182
72
14
14
Klonalität
Polyklonal
Konjugat
Dieser CCR5 Antikörper ist unkonjugiert
43
27
20
19
16
14
13
13
9
9
9
6
6
5
5
5
5
4
4
4
4
4
4
3
3
2
2
2
2
2
2
1
1
1
1
1
1
Applikation
Enzyme Immunoassay (EIA), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
302
206
139
65
63
57
56
33
29
18
14
12
8
5
5
4
4
3
2
2
2
2
2
2
2
1
1
1
Hersteller
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Bilder

Produktnummer ABIN372756
517,00 €
Zzgl. Versandkosten 20,00 € und MWSt
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anti-CCR5 Antikörper für Enzyme Immunoassay mit den meisten Publikationen

Ähnliche anti-CCR5 Antikörper

Applikation / Reaktivität Human
Activation (Act) 2 Antikörper
Cell-ELISA (cELISA) 1 Antikörper
Complement Mediated Cell Depletion (CMCD) 2 Antikörper
Cytometry by Time of Flight (CyTOF) 2 Antikörper
Depletion (Dep) 2 Antikörper
ELISA 128 Antikörper
ELISA (Detection) 2 Antikörper
Enzyme Immunoassay (EIA) 6 Antikörper
Flow Cytometry (FACS) 289 Antikörper
Fluorescence Microscopy (FM) 1 Antikörper
Functional Studies (Func) 17 Antikörper
Immunochromatography (IC) 1 Antikörper
Immunocytochemistry (ICC) 55 Antikörper
Immunofluorescence (IF) 66 Antikörper
Immunofluorescence (fixed cells) (IF/ICC) 3 Antikörper
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 14 Antikörper
Immunohistochemistry (IHC) 59 Antikörper

General

Antigen C-C Chemokine Receptor Type 5 (CCR5) Antikörper
Epitop AA 3-30, C-Term
(51), (35), (19), (15), (13), (12), (11), (10), (10), (9), (8), (7), (7), (6), (4), (3), (3), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reaktivität Human
(473), (81), (65), (14), (14), (3), (2), (1), (1), (1), (1), (1)
Wirt Ziege
(227), (182), (72), (14), (14)
Klonalität
Polyklonal
Konjugat Dieser CCR5 Antikörper ist unkonjugiert
(43), (27), (20), (19), (16), (14), (13), (13), (9), (9), (9), (6), (6), (5), (5), (5), (5), (4), (4), (4), (4), (4), (4), (3), (3), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1)
Applikation Enzyme Immunoassay (EIA), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(302), (206), (139), (65), (63), (57), (56), (33), (29), (18), (14), (12), (8), (5), (5), (4), (4), (3), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1)
Pubmed 2 Publikationen vorhanden
Hersteller Anmelden zum Anzeigen

Produktdetails anti-CCR5 Antikörper

Target Details CCR5 Anwendungsinformationen Handhabung ProductDetails: References for anti-CCR5 antibody (ABIN372756) Bilder
Sequenz Y3QVSSPIYDIN YYTSEPCQKI NVKQIAA3
Spezifität Recognizes Human CD195/CCR5.
Kreuzreaktivität (Details) Species reactivity (tested):Human.
Reinigung Immunoaffinity Chromatography.
Immunogen Synthetic peptide corresponding to aa 3-30 of the C-terminal domain of Human CD195/CCR5.
Isotyp IgG

Target Details CCR5

Produktdetails anti-CCR5 Antikörper Anwendungsinformationen Handhabung ProductDetails: References for anti-CCR5 antibody (ABIN372756) Bilder zurück nach oben
Antigen
Andere Bezeichnung CD195 / CCR5 (CCR5 Antibody Abstract)
Hintergrund The CC chemokine receptor 5 (CCR5) is a member of the CC-chemokine receptor family, and has the characteristic structure of a 7 transmembrane G protein-coupled receptor (GPCR). CCR5 regulates trafficking and effector functions of memory/effector Th1 cells, macrophages, NK cells, and immature dendritic cells. CCR5 and its ligands play an important role in viral pathogenesis. CCR5 represents the co-receptor for macrophage (M) and dual (T cell and M)-tropic immunodeficiency viruses. Together with the CD4 binding receptor, CCR5 plays a critical role in HIV entry into the target cells. Moreover, the CCR5 ligands macrophage inflammatory protein (MIP)-1 alpha, MIP-1 beta and RANTES act as endogenous inhibitors of HIV infection, making both CCR5 and its chemokine ligands attractive therapeutic targets for HIV infection. Recent studies have also highlighted the role of CCR5 in a variety of other human diseases, ranging from infectious and inflammatory diseases to cancer.Synonyms: C-C CKR-5, C-C chemokine receptor type 5, CC-CKR-5, CCR-5, CHEMR13, CMKBR5, HIV-1 fusion coreceptor
Gen-ID 1234
NCBI Accession NP_000570
UniProt P51681
Forschungsgebiet CD Antigens, Surface Receptors of Immune Cells, Chemokines, Receptors
Pathways Cellular Response to Molecule of Bacterial Origin, cAMP Metabolic Process, Regulation of Cell Size

Anwendungsinformationen

Produktdetails anti-CCR5 Antikörper Target Details CCR5 Handhabung ProductDetails: References for anti-CCR5 antibody (ABIN372756) Bilder zurück nach oben
Applikationshinweise ELISA: 1/100000. Western Blot: 1/1000. Immunocytochemistry: 1/300. Immunohistochemistry on Paraffin Sections: 5 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Beschränkungen Nur für Forschungszwecke einsetzbar

Handhabung

Produktdetails anti-CCR5 Antikörper Target Details CCR5 Anwendungsinformationen ProductDetails: References for anti-CCR5 antibody (ABIN372756) Bilder zurück nach oben
Buffer PBS containing 0.09 % Sodium Azide as preservative and 1 mg/mL BSA as stabilizer.
Konservierungsmittel Sodium azide
Vorsichtsmaßnahmen This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung Avoid repeated freezing and thawing.
Lagerung 4 °C/-20 °C
Informationen zur Lagerung Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

ProductDetails: References for anti-CCR5 antibody (ABIN372756)

Produktdetails anti-CCR5 Antikörper Target Details CCR5 Anwendungsinformationen Handhabung Bilder zurück nach oben
Allgemeine Veröffentlichungen

Tan, Goedegebuure, Belt, Flaherty, Sankpal, Gillanders, Eberlein, Hsieh, Linehan: "Disruption of CCR5-dependent homing of regulatory T cells inhibits tumor growth in a murine model of pancreatic cancer." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 182, Issue 3, pp. 1746-55, 2009

Moutsopoulos, Nares, Nikitakis, Rangel, Wen, Munson, Sauk, Wahl: "Tonsil epithelial factors may influence oropharyngeal human immunodeficiency virus transmission." in: The American journal of pathology, Vol. 171, Issue 2, pp. 571-9, 2007

Bilder

Produktdetails anti-CCR5 Antikörper Target Details CCR5 Anwendungsinformationen Handhabung ProductDetails: References for anti-CCR5 antibody (ABIN372756) zurück nach oben
Bilder des Herstellers
 image for anti-CCR5 Antikörper (C-C Chemokine Receptor Type 5) (AA 3-30) (ABIN372756) anti-C-C Chemokine Receptor Type 5 (CCR5) (AA 3-30), (C-Term) antibody