anti-Human CCR5 Antikörper für Cell-ELISA

Recommended CCR5 Antibody (geliefert von: Anmelden zum Anzeigen )

Antigen
C-C Chemokine Receptor Type 5 (CCR5) Antikörper
  • CC-CKR-5
  • CCCKR5
  • CCR-5
  • CD195
  • CKR-5
  • CKR5
  • CMKBR5
  • IDDM22
  • Ckr5
  • Cmkbr5
  • CCR1-L
  • GPCR
  • CCR5
  • AM4-7
  • CCR5-L
  • chemokine (C-C motif) receptor 5 (gene/pseudogene)
  • chemokine (C-C motif) receptor 5
  • chemokine (C-C motif) receptor 2
  • C-C chemokine receptor type 5-like
  • CCR5
  • Ccr5
  • CCR2
  • LOC100399144
Reaktivität
Human
517
87
72
14
14
3
2
1
1
1
1
1
Wirt
Maus
270
182
72
15
14
Klonalität
Monoklonal
Konjugat
Dieser CCR5 Antikörper ist unkonjugiert
47
27
24
23
20
17
15
14
13
13
13
8
6
6
5
5
5
5
4
4
4
4
4
3
3
2
2
2
2
2
2
1
1
1
1
1
1
Applikation
Cell-ELISA (cELISA), Flow Cytometry (FACS), ELISA
345
210
140
66
64
58
57
33
29
18
14
12
12
8
6
5
4
4
3
3
2
2
2
2
1
1
Hersteller
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Bilder

Produktnummer ABIN1381740
$ 386.93
Zzgl. Versandkosten $45.00

General

Antigen C-C Chemokine Receptor Type 5 (CCR5) Antikörper
Reaktivität Human
(517), (87), (72), (14), (14), (3), (2), (1), (1), (1), (1), (1)
Wirt Maus
(270), (182), (72), (15), (14)
Klonalität (Klon)
Monoklonal   ( )
Konjugat Dieser CCR5 Antikörper ist unkonjugiert
(47), (27), (24), (23), (20), (17), (15), (14), (13), (13), (13), (8), (6), (6), (5), (5), (5), (5), (4), (4), (4), (4), (4), (3), (3), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1)
Applikation Cell-ELISA (cELISA), Flow Cytometry (FACS), ELISA
(345), (210), (140), (66), (64), (58), (57), (33), (29), (18), (14), (12), (12), (8), (6), (5), (4), (4), (3), (3), (2), (2), (2), (2), (1), (1)
Pubmed 5 Publikationen vorhanden
Hersteller Anmelden zum Anzeigen

Produktdetails anti-CCR5 Antikörper

Target Details CCR5 Anwendungsinformationen Handhabung Referenzen für anti-CCR5 Antikörper (ABIN1381740) Bilder
Spezifität Anti-human CCR5
Produktmerkmale Selection: Based on recognition of the complete native protein expressed on transfected mammalian cells
Reinigung Protein G
Immunogen genetic immunization with cDNA encoding human CCR5 SwissProt / UniProt P51681
Klon NP-6G4
Isotyp IgG1

Target Details CCR5

Produktdetails anti-CCR5 Antikörper Anwendungsinformationen Handhabung Referenzen für anti-CCR5 Antikörper (ABIN1381740) Bilder zurück nach oben
Antigen
Andere Bezeichnung CCR5 (CCR5 Antibody Abstract)
Hintergrund CCR5 (CC chemokine receptor 5) belongs to the rhodopsin family of G-protein-coupled receptors. Chemokine receptors are membrane-bound molecules composed of 7-transmembrane domains and are coupled to G-proteins. CCR5 binds the chemokines MIP-1β, RANTES, MIP-1, and MCP-2 specifically using transfected and peripheral blood mononuclear cells. It is highly expressed in lymphoid organs such as the thymus and spleen and in peripheral T lymphocytes and macrophages. CCR5 has been shown to be the major coreceptor in association with CD4 for macrophage-tropic HIV-1 entry into permissive cells.
UniProt P51681
Forschungsgebiet Cardiovascular, Atherosclerosis, Innate Immunity, Chemokines, Alzheimer's Disease, Receptors, CD Antigens, Signaling
Pathways Cellular Response to Molecule of Bacterial Origin, cAMP Metabolic Process, Regulation of Cell Size

Anwendungsinformationen

Produktdetails anti-CCR5 Antikörper Target Details CCR5 Handhabung Referenzen für anti-CCR5 Antikörper (ABIN1381740) Bilder zurück nach oben
Applikationshinweise Flow cytometry: 1.2 µg/10^6 cells
CELISA: 1:200 - 1:400
ELISA: 1:200 - 1:400
For each application a titration should be performed to determine the optimal concentration.
Kommentare

Synonyms: CC chemokine receptor 5

Beschränkungen Nur für Forschungszwecke einsetzbar

Handhabung

Produktdetails anti-CCR5 Antikörper Target Details CCR5 Anwendungsinformationen Referenzen für anti-CCR5 Antikörper (ABIN1381740) Bilder zurück nach oben
Buffer PBS, pH 7.2
Handhabung Avoid repeated freezing and thawing.
Lagerung 4 °C
Informationen zur Lagerung short term: 2 °C - 8 °C, long term: -20 °C

Referenzen für anti-CCR5 Antikörper (ABIN1381740)

Produktdetails anti-CCR5 Antikörper Target Details CCR5 Anwendungsinformationen Handhabung Bilder zurück nach oben
Allgemeine Veröffentlichungen

Murdoch, Finn: "Chemokine receptors and their role in inflammation and infectious diseases." in: Blood, Vol. 95, Issue 10, pp. 3032-43, 2000

Ruffing, Sullivan, Sharmeen, Sodroski, Wu: "CCR5 has an expanded ligand-binding repertoire and is the primary receptor used by MCP-2 on activated T cells." in: Cellular immunology, Vol. 189, Issue 2, pp. 160-8, 1998

Samson, Labbe, Mollereau, Vassart, Parmentier: "Molecular cloning and functional expression of a new human CC-chemokine receptor gene." in: Biochemistry, Vol. 35, Issue 11, pp. 3362-7, 1996

Raport, Gosling, Schweickart, Gray, Charo: "Molecular cloning and functional characterization of a novel human CC chemokine receptor (CCR5) for RANTES, MIP-1beta, and MIP-1alpha." in: The Journal of biological chemistry, Vol. 271, Issue 29, pp. 17161-6, 1996

Doranz, Rucker, Yi, Smyth, Samson, Peiper, Parmentier, Collman, Doms: "A dual-tropic primary HIV-1 isolate that uses fusin and the beta-chemokine receptors CKR-5, CKR-3, and CKR-2b as fusion cofactors." in: Cell, Vol. 85, Issue 7, pp. 1149-58, 1996

Bilder

Produktdetails anti-CCR5 Antikörper Target Details CCR5 Anwendungsinformationen Handhabung Referenzen für anti-CCR5 Antikörper (ABIN1381740) zurück nach oben
Bilder des Herstellers
Flow Cytometry (FACS) image for anti-C-C Chemokine Receptor Type 5 (CCR5) antibody (ABIN1381740) . BOSC23 cells were transiently transfected with an expression vector encoding either...
SDS-PAGE (SDS) image for anti-C-C Chemokine Receptor Type 5 (CCR5) antibody (ABIN1381740) SDS-PAGE analysis of purified NP-6G4 monoclonal antibody. Lane 1: molecular weight ma...