Use your antibodies-online credentials, if available.
Keine Produkte auf Ihrer Vergleichsliste.
Ihr Warenkorb ist leer.
Alle Spezies anzeigen
Weitere Synonyme anzeigen
Wählen Sie die Spezies und Applikation aus
anti-Mouse (Murine) Antikörper:
anti-Rat (Rattus) Antikörper:
Sie gelangen zu unserer vorgefilterten Suche.
Human Polyclonal PTBP2 Primary Antibody für ELISA, WB - ABIN566177
Rolland, Evrard, Guitton, Lavigne, Calvel, Couvet, Jégou, Pineau: Two-dimensional fluorescence difference gel electrophoresis analysis of spermatogenesis in the rat. in Journal of proteome research 2007
Show all 6 Pubmed References
Human Monoclonal PTBP2 Primary Antibody für ELISA, WB - ABIN566178
Xue, Zhou, Wu, Zhu, Ji, Kwon, Zhang, Yeo, Black, Sun, Fu, Zhang: Genome-wide analysis of PTB-RNA interactions reveals a strategy used by the general splicing repressor to modulate exon inclusion or skipping. in Molecular cell 2010
Show all 2 Pubmed References
Human Polyclonal PTBP2 Primary Antibody für ELISA - ABIN262285
Boutz, Stoilov, Li, Lin, Chawla, Ostrow, Shiue, Ares, Black: A post-transcriptional regulatory switch in polypyrimidine tract-binding proteins reprograms alternative splicing in developing neurons. in Genes & development 2007
Cow (Bovine) Polyclonal PTBP2 Primary Antibody für WB - ABIN2776545
Tateiwa, Gotoh, Ichikawa, Kikuchi, Yoshimura: Molecular cloning and characterization of human PTB-like protein: a possible retinal autoantigen of cancer-associated retinopathy. in Journal of neuroimmunology 2001
It has been established that PTBP1 (zeige PTBP1 Antikörper) and PTBP2 are members of a family of cryptic exon repressors.
PTBP1 (zeige PTBP1 Antikörper) and PTBP2 impaired autoregulation of SRSF3 (zeige SRSF3 Antikörper) in oral squamous cell carcinoma cancer cells.
Data show that polypyrimidine tract-binding (zeige PTBP1 Antikörper) proteins nPTB and ROD1 (zeige PTBP3 Antikörper) interact with mitochondrial tRNA(Thr (zeige TRH Antikörper)) in the cytoplasm outside of mitochondria.
In T98G glioma cells, the level of sumoylated PTBP2 was reduced compared to that of normal brain cells. Overall, this study shows that PTBP2 is posttranslationally modified by SUMO1 (zeige SUMO1 Antikörper).
MALAT1 binds to SFPQ (zeige SFPQ Antikörper) releasing PTBP2 from the SFPQ (zeige SFPQ Antikörper)/PTBP2 complex, the increased SFPQ (zeige SFPQ Antikörper)-detached PTBP2 promotes cell proliferation and migration in colorectal cancer.
Defining the multifunctional roles of PTB (zeige PTBP1 Antikörper) will contribute to the understanding of key regulatory events in gene expression.
Changes in miR (zeige MLXIP Antikörper)-223/PTBP2 pathway could contribute of abnormal splicing in chronic myeloid leukemia (zeige BCL11A Antikörper).
Regulation of the mutually exclusive exons 8a and 8 in the CaV1.2 (zeige CACNA1C Antikörper) calcium channel transcript by polypyrimidine tract-binding protein (zeige PTBP1 Antikörper).
present fluorescence, NMR, and in vivo splicing data in support of a role of PTB (zeige PTBP1 Antikörper) in inducing RNA loops. We show that the RNA recognition motifs (RRMs) 3 and 4 of PTB (zeige PTBP1 Antikörper) can bind two distant pyrimidine tracts and bring their 5' and 3' ends in close proximity
The nPTB proximal promoter, although rich in G+C content and presenting putative binding sites for the transcription factors Sp1 (zeige PSG1 Antikörper), NF-1 (zeige NF1 Antikörper), NF-kB and Oct-1 (zeige POU2F1 Antikörper), lacks a typical TATA box.
This knockin Ptbp1 (zeige PTBP1 Antikörper) rescued a forebrain-specific, but not a pan (zeige SUPT6H Antikörper)-neuronal, Ptbp2 knockout, demonstrating both redundant and distinct roles for the proteins. Many developmentally regulated exons exhibited different sensitivities to PTBP1 (zeige PTBP1 Antikörper) and PTBP2.
Ptbp2 is an essential factor in heat stress-induced sperm cell injury and non-obstructive azoospermia.
Ptbp2 ablation results in germ cell loss due to increased apoptosis of meiotic spermatocytes and postmeiotic arrest of spermatid differentiation.
These results define a new genetic regulatory program, where PTBP2 acts to temporarily repress expression of adult protein isoforms until the final maturation of the neuron.
Thus, Ptbp2 inhibition of a discrete set of adult neuronal exons underlies early brain development prior to neuronal differentiation and is essential for postnatal survival.
The expression of PSD-95 (zeige DLG4 Antikörper) during early neural development is controlled at the RNA level by two PTB (zeige PTBP1 Antikörper) proteins whose sequential downregulation is necessary for synapse maturation.
The present study provides evidence that alternative neuronal nPTB and Fox-1 (zeige A2BP1 Antikörper)/Fox-2 (zeige RBM9 Antikörper) isoforms are also produced in lenses
Reduction of PTBP2 levels led to decreases in 7 of 10 of the mRNAs, to the repression of alternative splicing of introns, and to reductions in specific miRNAs.
The predominant expression of REST4, HuB/C/D and nPTB in post-mitotic fiber cells, together with miR (zeige MLXIP Antikörper)-124 expression in vertebrate lenses, was shown.
Two stretches of polypyrimidine tracts designated PPT1 and PPT2 which influence the IRES activity of cx55.5 protein were identified; deletion of PPT2 results in a complete loss of the IRES activity
The protein encoded by this gene binds to the intronic cluster of RNA regulatory elements, downstream control sequence (DCS). It is implicated in controlling the assembly of other splicing-regulatory proteins. This protein is very similar to the polypyrimidine tract binding protein but it is expressed primarily in the brain.
, neural polypyrimidine tract binding protein
, neural polypyrimidine tract-binding protein
, neurally-enriched homolog of PTB
, polypyrimidine tract-binding protein 2
, splicing regulator
, RRM-type RNA-binding protein brPTB
, brain-enriched PTB
, brain-enriched polypyrimidine tract-binding protein
, polypyrimidine tract binding protein 2
, polypyrimidine tract-binding protein 2-like