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anti-Hepatitis A Virus Cellular Receptor 2 (HAVCR2) Antikörper

Bezeichnung:
anti-Hepatitis A Virus Cellular Receptor 2 Antikörper (HAVCR2)
Auf www.antikoerper-online.de finden Sie aktuell 198 Hepatitis A Virus Cellular Receptor 2 (HAVCR2) Antikörper von 22 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen Hepatitis A Virus Cellular Receptor 2 Proteine (35) und Hepatitis A Virus Cellular Receptor 2 Kits (7) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 254 Hepatitis A Virus Cellular Receptor 2 Produkte verfügbar.
Synonyme:
HAVcr-2, HAVCR2, KIM-3, MGC140131, TIM-3, tim3, TIMD-3, Timd3
Alle Antikörper anzeigen Gen GeneID UniProt
HAVCR2 84868 Q8TDQ0
HAVCR2 171285 Q8VIM0
HAVCR2 363578  

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Am meisten referenzierte anti-Hepatitis A Virus Cellular Receptor 2 Antikörper

  1. Human Monoclonal HAVCR2 Primary Antibody für FACS - ABIN4896442 : Tandon, Giret, Sengupta, York, Wiznia, Rosenberg, Kallas, Ndhlovu, Nixon: Age-related expansion of Tim-3 expressing T cells in vertically HIV-1 infected children. in PLoS ONE 2012 (PubMed)
    Zeige alle 15 Referenzen für ABIN4896442

  2. Human Monoclonal HAVCR2 Primary Antibody für FACS - ABIN4896438 : Raziorrouh, Heeg, Kurktschiev, Schraut, Zachoval, Wendtner, Wächtler, Spannagl, Denk, Ulsenheimer, Bengsch, Pircher, Diepolder, Grüner, Jung: Inhibitory phenotype of HBV-specific CD4+ T-cells is characterized by high PD-1 expression but absent coregulation of multiple inhibitory molecules. in PLoS ONE 2014 (PubMed)
    Zeige alle 5 Referenzen für ABIN4896438

  3. Human Monoclonal HAVCR2 Primary Antibody für FACS - ABIN4899648 : Hertoghs, Moerland, van Stijn, Remmerswaal, Yong, van de Berg, van Ham, Baas, ten Berge, van Lier: Molecular profiling of cytomegalovirus-induced human CD8+ T cell differentiation. in The Journal of clinical investigation 2010 (PubMed)
    Zeige alle 5 Referenzen für ABIN4899648

  4. Mouse (Murine) Monoclonal HAVCR2 Primary Antibody für FACS - ABIN4896162 : Cho, Roche, Sandall, Brass, Seed, Xavier, Medoff: Enhanced Tim3 activity improves survival after influenza infection. in Journal of immunology (Baltimore, Md. : 1950) 2012 (PubMed)
    Zeige alle 3 Referenzen für ABIN4896162

  5. Mouse (Murine) Monoclonal HAVCR2 Primary Antibody für FACS - ABIN4896159 : Yadav, Jhunjhunwala, Phung, Lupardus, Tanguay, Bumbaca, Franci, Cheung, Fritsche, Weinschenk, Modrusan, Mellman, Lill, Delamarre: Predicting immunogenic tumour mutations by combining mass spectrometry and exome sequencing. in Nature 2014 (PubMed)
    Zeige alle 2 Referenzen für ABIN4896159

  6. Human Monoclonal HAVCR2 Primary Antibody für FACS - ABIN4896440 : Leeansyah, Svärd, Dias, Buggert, Nyström, Quigley, Moll, Sönnerborg, Nowak, Sandberg: Arming of MAIT Cell Cytolytic Antimicrobial Activity Is Induced by IL-7 and Defective in HIV-1 Infection. in PLoS pathogens 2015 (PubMed)
    Zeige alle 2 Referenzen für ABIN4896440

  7. Human Monoclonal HAVCR2 Primary Antibody für FACS - ABIN4896439 : Lasso, Mateus, Pavía, Rosas, Roa, Thomas, López, González, Puerta, Cuéllar: Inhibitory Receptor Expression on CD8+ T Cells Is Linked to Functional Responses against Trypanosoma cruzi Antigens in Chronic Chagasic Patients. in Journal of immunology (Baltimore, Md. : 1950) 2015 (PubMed)
    Zeige alle 2 Referenzen für ABIN4896439

  8. Human Polyclonal HAVCR2 Primary Antibody für ELISA, WB - ABIN185571 : Meyers, Sabatos, Chakravarti, Kuchroo: The TIM gene family regulates autoimmune and allergic diseases. in Trends in molecular medicine 2005 (PubMed)

  9. Dog (Canine) Polyclonal HAVCR2 Primary Antibody für WB - ABIN2782255 : Nuchnoi, Ohashi, Kimura, Hananantachai, Naka, Krudsood, Looareesuwan, Tokunaga, Patarapotikul: Significant association between TIM1 promoter polymorphisms and protection against cerebral malaria in Thailand. in Annals of human genetics 2008 (PubMed)

  10. Human Monoclonal HAVCR2 Primary Antibody für FACS - ABIN4896441 : Lanteri, Diamond, Law, Chew, Wu, Inglis, Wong, Busch, Norris, Ndhlovu: Increased frequency of Tim-3 expressing T cells is associated with symptomatic West Nile virus infection. in PLoS ONE 2014 (PubMed)

Weitere Antikörper gegen Hepatitis A Virus Cellular Receptor 2 Interaktionspartner

Cow (Bovine) Hepatitis A Virus Cellular Receptor 2 (HAVCR2) Interaktionspartner

  1. The Tim-3/Gal-9 (zeige LGALS9 Antikörper) pathway might link disease progression with T cell exhaustion during bovine leukemia virus infection.

Human Hepatitis A Virus Cellular Receptor 2 (HAVCR2) Interaktionspartner

  1. these data suggest that the high Tim-3 expression in monocytes could be utilized by tumor-promoting Gal-9 (zeige LGALS9 Antikörper) expression on CD4 (zeige CD4 Antikörper)(+) T cells

  2. In conclusion, Tim-3 on immune cells negatively regulates cell-mediated immunity against Plasmodium infection, and blocking Tim-3 signaling enhances sterile immunity and may play a protective role during malarial parasite infections.

  3. this study shows that the transcription factor T-bet controls Tim-3-mediated inhibition of monocyte/macrophage function during chronic hepatitis C virus infection

  4. this study shows that TIM-3 expressed on myeloid leukaemia cells may facilitate functional exhaustion in T helper cells

  5. this study shows that in osteosarcoma patients, Tim3 expression did not directly mediate immune suppression, but the interaction between Tim3+ T cells and monocytes, naive CD4 (zeige CD4 Antikörper)+ T cells, and Gal9-expressing CD4 (zeige CD4 Antikörper)+ CD25 (zeige IL2RA Antikörper)+ Tregs could resulting in progressive suppression of Th1 (zeige TH1L Antikörper) responses

  6. the present study demonstrated that interference with Tim-3 expression using siRNA may attenuate ccRCC invasion by aggravating anoikis following cell detachment.

  7. Elevated frequencies of CD8 (zeige CD8A Antikörper) T cells expressing PD-1 (zeige PDCD1 Antikörper), CTLA-4 (zeige CTLA4 Antikörper) and Tim-3 were found within tumor from perineural squamous cell carcinoma patients.

  8. Tim-3 blockade in combination with TLR activation induces the expression of antiviral molecules without a significant increase in TNF-alpha (zeige TNF Antikörper) or SOCS1 (zeige SOCS1 Antikörper).

  9. this study shows that the expression of TIM-3 is correlated with advanced stage and could be independent risk factors for colorectal cancer

  10. Immune checkpoint proteins are co-inhibitory factors that can diminish the antigen-specific immune responses by attenuating the regulatory role of cytotoxic T-lymphocyte-associated protein 4 (zeige CTLA4 Antikörper), programmed cell death-1 (zeige PDCD1 Antikörper), lymphocyte-activation gene 3 (zeige LAG3 Antikörper), and T-cell immunoglobulin mucin-3.

Mouse (Murine) Hepatitis A Virus Cellular Receptor 2 (HAVCR2) Interaktionspartner

  1. Methylation level of the TIM-3 promoter gradually decreased after each round of T-cell polarization, and this decrease was inversely correlated with TIM-3 expression.

  2. in mice, TIM-3 is not essential for development of HDM (zeige HDAC3 Antikörper)-induced acute or chronic allergic airway inflammation, although it appears to be involved in reduced lymphocyte recruitment during HDM (zeige HDAC3 Antikörper)-induced chronic allergic airway inflammation.

  3. Authors found that a CD8 (zeige CD8A Antikörper)(+) T-cell population with age-associated exhaustion was distinguishable by its expression of Tim-3.

  4. TIM4 (zeige TIMD4 Antikörper) binds TIM3 on the surface of polarized Th1 (zeige HAND1 Antikörper) cells to induce Th1 (zeige HAND1 Antikörper) cell apoptosis, which may contribute to the development of Th2-dominant immune disorders.

  5. The Gal-9 (zeige LGALS9 Antikörper)/Tim-3 signal is important for the regulation of decidua NK cells function, which is beneficial for the maintenance of a normal pregnancy.

  6. TIM-3 expression by NK cells and gamma/delta T cells is similar in the peripheral and decidual immune cells from pregnant mice.

  7. Tim-3 acts at a receptor-proximal point to enhance Lyn (zeige LYN Antikörper) kinase-dependent signaling pathways that modulate both immediate-phase degranulation and late-phase cytokine production downstream of FcepsilonRI (zeige FCER1A Antikörper) ligation.

  8. Our data indicate that Tim-3 expression on NK cells is regulated by T-bet, and that Tim-3 levels correlate with advanced stages of gastric cancer

  9. TIM-3 plays a role in regulating the uterine natural killer cells and contributes to the maintenance of tolerance at the feto-maternal interface.

  10. TIM-3 is highly expressed in hypoxic brain regions of a mouse cerebral hypoxia-ischaemia (H/I) model. TIM-3 is distinctively upregulated in activated microglia and astrocytes in a HIF-1 (zeige HIF1A Antikörper)-dependent manner.

Hepatitis A Virus Cellular Receptor 2 (HAVCR2) Antigen-Profil

Beschreibung des Gens

The protein encoded by this gene belongs to the immunoglobulin superfamily, and TIM family of proteins. CD4-positive T helper lymphocytes can be divided into types 1 (Th1) and 2 (Th2) on the basis of their cytokine secretion patterns. Th1 cells are involved in cell-mediated immunity to intracellular pathogens and delayed-type hypersensitivity reactions, whereas, Th2 cells are involved in the control of extracellular helminthic infections and the promotion of atopic and allergic diseases. This protein is a Th1-specific cell surface protein that regulates macrophage activation, and inhibits Th1-mediated auto- and alloimmune responses, and promotes immunological tolerance.

Alternative names and synonyms associated with Hepatitis A Virus Cellular Receptor 2 (HAVCR2)

  • hepatitis A virus cellular receptor 2 (HAVCR2) Antikörper
  • hepatitis A virus cellular receptor 2 (Havcr2) Antikörper
  • HAVcr-2 Antikörper
  • HAVCR2 Antikörper
  • KIM-3 Antikörper
  • MGC140131 Antikörper
  • TIM-3 Antikörper
  • tim3 Antikörper
  • TIMD-3 Antikörper
  • Timd3 Antikörper

Bezeichner auf Proteinebene für HAVCR2

hepatitis A virus cellular receptor 2 , T cell immunoglobulin mucin 3 , T cell immunoglobulin mucin-3 , T-cell immunoglobulin and mucin domain-containing protein 3 , T-cell membrane protein 3 , kidney injury molecule-3 , HAVcr-2 , T-cell immunoglobulin and mucin domain containing 3 , TIMD-3 , hepatitis A virus cellular receptor 2 homolog , TIM-3

GENE ID SPEZIES
462219 Pan troglodytes
768047 Bos taurus
84868 Homo sapiens
171285 Mus musculus
363578 Rattus norvegicus
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