anti-Hepatitis A Virus Cellular Receptor 2 (HAVCR2) Antikörper

Bezeichnung:
anti-Hepatitis A Virus Cellular Receptor 2 Antikörper (HAVCR2)
Auf www.antikoerper-online.de finden Sie aktuell 216 Hepatitis A Virus Cellular Receptor 2 (HAVCR2) Antikörper von 24 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen Hepatitis A Virus Cellular Receptor 2 Proteine (41) und Hepatitis A Virus Cellular Receptor 2 Kits (8) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 279 Hepatitis A Virus Cellular Receptor 2 Produkte verfügbar.
Synonyme:
HAVcr-2, HAVCR2, KIM-3, MGC140131, TIM-3, tim3, TIMD-3, Timd3
Alle Antikörper anzeigen Gen GeneID UniProt
HAVCR2 84868 Q8TDQ0
HAVCR2 171285 Q8VIM0
HAVCR2 363578  

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Am meisten referenzierte anti-Hepatitis A Virus Cellular Receptor 2 Antikörper

  1. Human Monoclonal HAVCR2 Primary Antibody für FACS - ABIN4896442 : Tandon, Giret, Sengupta, York, Wiznia, Rosenberg, Kallas, Ndhlovu, Nixon: Age-related expansion of Tim-3 expressing T cells in vertically HIV-1 infected children. in PLoS ONE 2012 (PubMed)
    Zeige alle 15 Referenzen für 4896442

  2. Human Monoclonal HAVCR2 Primary Antibody für FACS - ABIN4899648 : Hertoghs, Moerland, van Stijn, Remmerswaal, Yong, van de Berg, van Ham, Baas, ten Berge, van Lier: Molecular profiling of cytomegalovirus-induced human CD8+ T cell differentiation. in The Journal of clinical investigation 2010 (PubMed)
    Zeige alle 5 Referenzen für 4899648

  3. Human Monoclonal HAVCR2 Primary Antibody für FACS - ABIN4896438 : Raziorrouh, Heeg, Kurktschiev, Schraut, Zachoval, Wendtner, Wächtler, Spannagl, Denk, Ulsenheimer, Bengsch, Pircher, Diepolder, Grüner, Jung: Inhibitory phenotype of HBV-specific CD4+ T-cells is characterized by high PD-1 expression but absent coregulation of multiple inhibitory molecules. in PLoS ONE 2014 (PubMed)
    Zeige alle 5 Referenzen für 4896438

  4. Mouse (Murine) Monoclonal HAVCR2 Primary Antibody für FACS - ABIN4896162 : Cho, Roche, Sandall, Brass, Seed, Xavier, Medoff: Enhanced Tim3 activity improves survival after influenza infection. in Journal of immunology (Baltimore, Md. : 1950) 2012 (PubMed)
    Zeige alle 3 Referenzen für 4896162

  5. Mouse (Murine) Monoclonal HAVCR2 Primary Antibody für FACS - ABIN4896159 : Yadav, Jhunjhunwala, Phung, Lupardus, Tanguay, Bumbaca, Franci, Cheung, Fritsche, Weinschenk, Modrusan, Mellman, Lill, Delamarre: Predicting immunogenic tumour mutations by combining mass spectrometry and exome sequencing. in Nature 2014 (PubMed)
    Zeige alle 2 Referenzen für 4896159

  6. Human Monoclonal HAVCR2 Primary Antibody für FACS - ABIN4896440 : Leeansyah, Svärd, Dias, Buggert, Nyström, Quigley, Moll, Sönnerborg, Nowak, Sandberg: Arming of MAIT Cell Cytolytic Antimicrobial Activity Is Induced by IL-7 and Defective in HIV-1 Infection. in PLoS pathogens 2015 (PubMed)
    Zeige alle 2 Referenzen für 4896440

  7. Human Monoclonal HAVCR2 Primary Antibody für FACS - ABIN4896439 : Lasso, Mateus, Pavía, Rosas, Roa, Thomas, López, González, Puerta, Cuéllar: Inhibitory Receptor Expression on CD8+ T Cells Is Linked to Functional Responses against Trypanosoma cruzi Antigens in Chronic Chagasic Patients. in Journal of immunology (Baltimore, Md. : 1950) 2015 (PubMed)
    Zeige alle 2 Referenzen für 4896439

  8. Dog (Canine) Polyclonal HAVCR2 Primary Antibody für WB - ABIN2782255 : Nuchnoi, Ohashi, Kimura, Hananantachai, Naka, Krudsood, Looareesuwan, Tokunaga, Patarapotikul: Significant association between TIM1 promoter polymorphisms and protection against cerebral malaria in Thailand. in Annals of human genetics 2008 (PubMed)

  9. Human Polyclonal HAVCR2 Primary Antibody für ELISA, WB - ABIN185571 : Meyers, Sabatos, Chakravarti, Kuchroo: The TIM gene family regulates autoimmune and allergic diseases. in Trends in molecular medicine 2005 (PubMed)

  10. Human Monoclonal HAVCR2 Primary Antibody für FACS - ABIN4896441 : Lanteri, Diamond, Law, Chew, Wu, Inglis, Wong, Busch, Norris, Ndhlovu: Increased frequency of Tim-3 expressing T cells is associated with symptomatic West Nile virus infection. in PLoS ONE 2014 (PubMed)

Weitere Antikörper gegen Hepatitis A Virus Cellular Receptor 2 Interaktionspartner

Cow (Bovine) Hepatitis A Virus Cellular Receptor 2 (HAVCR2) Interaktionspartner

  1. The Tim-3/Gal-9 (zeige LGALS9 Antikörper) pathway might link disease progression with T cell exhaustion during bovine leukemia virus infection.

Human Hepatitis A Virus Cellular Receptor 2 (HAVCR2) Interaktionspartner

  1. this study shows that severe aplastic anemia untreated patients have lower TIM-3 expression on NK cells and CD56dim NK subsets compared with normal controls, and are correlated with the severity of pancytopenia of SAA (zeige SAA1 Antikörper)

  2. We conclude that Tim-3 is a biomarker of dysfunctional plasmacytoid dendritic cells

  3. The present study defines the minimal TIM-3 promoter region and demonstrates its interaction with c-Jun (zeige JUN Antikörper) during TIM-3 transcription in CD4 (zeige CD4 Antikörper)(+) T cells.

  4. Our findings establish intratumoral Tim-3(+)PD1 (zeige PDCD1 Antikörper)(+)CD8 (zeige CD8A Antikörper)(+) T cells as critical mediators of an aggressive phenotype in RCC (zeige XRCC1 Antikörper).

  5. Osteosarcoma patients with higher Tim-3 had relatively lower survival. Multivariate analyses for overall survival revealed that high serum soluble Tim-3 level was an independent prognostic factor for osteosarcoma

  6. urther analyses revealed that the levels of Tim-3 on CD4 (zeige CD4 Antikörper)+ T cells and CD8 (zeige CD8A Antikörper)+ T cells exhibited different expression patterns in terms of localization depending on pathological category of prostate cancer and metastasis. Immunohistochemical analysis revealed that positive staining of Tim-3 in prostate cancer but little or no staining of Tim-3 was observed in benign prostate hyperplasia epithelium.

  7. this review discusses the recent findings on Tim-3, the role it plays in regulating immune responses in different cell types and the rationale for targeting Tim-3 for effective cancer immunotherapy

  8. The -1516G > T, -574G > T and +4259T > G SNPs within TIM-3 gene might play an important role as a genetic risk factor in the pathogenesis of ET.

  9. this study shows that that Tim-3 expression defines a subpopulation of PD-1 (zeige PDCD1 Antikörper)+ exhausted NY-ESO-1 (zeige CTAG1B Antikörper)-specific CD8 (zeige CD8A Antikörper)+ T cell and PD-1 (zeige PDCD1 Antikörper)+Tim-3+ CD8 (zeige CD8A Antikörper)+ T cells represented the largest subset of NY-ESO-1 (zeige CTAG1B Antikörper)-specific CD8 (zeige CD8A Antikörper)+ T cells in gastric cancer patients

  10. Increased TIM3+CD8 (zeige CD8A Antikörper)+T cells with lower perforin (zeige PRF1 Antikörper) and granzyme B (zeige Gzmb Antikörper) expression and higher CD95 (zeige FAS Antikörper) expression in MDS (zeige PAFAH1B1 Antikörper) patients had been observed. These findings suggested that TIM3 might be related to CD8 (zeige CD8A Antikörper)+T cells defect.

Mouse (Murine) Hepatitis A Virus Cellular Receptor 2 (HAVCR2) Interaktionspartner

  1. demonstrated that both IL-10 (zeige IL10 Antikörper) and TGF-beta (zeige TGFB1 Antikörper) upregulated TIM-3 surface expression on dendritic cells via a common signaling pathway that involved sequential activation of c-Src (zeige SRC Antikörper) and Bruton's tyrosine kinase (zeige BTK Antikörper)

  2. Methylation level of the TIM-3 promoter gradually decreased after each round of T-cell polarization, and this decrease was inversely correlated with TIM-3 expression.

  3. in mice, TIM-3 is not essential for development of HDM (zeige HDAC3 Antikörper)-induced acute or chronic allergic airway inflammation, although it appears to be involved in reduced lymphocyte recruitment during HDM (zeige HDAC3 Antikörper)-induced chronic allergic airway inflammation.

  4. Authors found that a CD8 (zeige CD8A Antikörper)(+) T-cell population with age-associated exhaustion was distinguishable by its expression of Tim-3.

  5. TIM4 (zeige TIMD4 Antikörper) binds TIM3 on the surface of polarized Th1 (zeige HAND1 Antikörper) cells to induce Th1 (zeige HAND1 Antikörper) cell apoptosis, which may contribute to the development of Th2-dominant immune disorders.

  6. The Gal-9 (zeige LGALS9 Antikörper)/Tim-3 signal is important for the regulation of decidua NK cells function, which is beneficial for the maintenance of a normal pregnancy.

  7. TIM-3 expression by NK cells and gamma/delta T cells is similar in the peripheral and decidual immune cells from pregnant mice.

  8. Tim-3 acts at a receptor-proximal point to enhance Lyn (zeige LYN Antikörper) kinase-dependent signaling pathways that modulate both immediate-phase degranulation and late-phase cytokine production downstream of FcepsilonRI (zeige FCER1A Antikörper) ligation.

  9. Our data indicate that Tim-3 expression on NK cells is regulated by T-bet, and that Tim-3 levels correlate with advanced stages of gastric cancer

  10. TIM-3 plays a role in regulating the uterine natural killer cells and contributes to the maintenance of tolerance at the feto-maternal interface.

Hepatitis A Virus Cellular Receptor 2 (HAVCR2) Antigen-Profil

Beschreibung des Gens

The protein encoded by this gene belongs to the immunoglobulin superfamily, and TIM family of proteins. CD4-positive T helper lymphocytes can be divided into types 1 (Th1) and 2 (Th2) on the basis of their cytokine secretion patterns. Th1 cells are involved in cell-mediated immunity to intracellular pathogens and delayed-type hypersensitivity reactions, whereas, Th2 cells are involved in the control of extracellular helminthic infections and the promotion of atopic and allergic diseases. This protein is a Th1-specific cell surface protein that regulates macrophage activation, and inhibits Th1-mediated auto- and alloimmune responses, and promotes immunological tolerance.

Alternative names and synonyms associated with Hepatitis A Virus Cellular Receptor 2 (HAVCR2)

  • hepatitis A virus cellular receptor 2 (HAVCR2) Antikörper
  • hepatitis A virus cellular receptor 2 (Havcr2) Antikörper
  • HAVcr-2 Antikörper
  • HAVCR2 Antikörper
  • KIM-3 Antikörper
  • MGC140131 Antikörper
  • TIM-3 Antikörper
  • tim3 Antikörper
  • TIMD-3 Antikörper
  • Timd3 Antikörper

Bezeichner auf Proteinebene für HAVCR2

hepatitis A virus cellular receptor 2 , T cell immunoglobulin mucin 3 , T cell immunoglobulin mucin-3 , T-cell immunoglobulin and mucin domain-containing protein 3 , T-cell membrane protein 3 , kidney injury molecule-3 , HAVcr-2 , T-cell immunoglobulin and mucin domain containing 3 , TIMD-3 , hepatitis A virus cellular receptor 2 homolog , TIM-3

GENE ID SPEZIES
462219 Pan troglodytes
768047 Bos taurus
84868 Homo sapiens
171285 Mus musculus
363578 Rattus norvegicus
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