BMP2 Proteine (BMP2)

Bezeichnung:
Bone Morphogenetic Protein 2 Proteine (BMP2)
Auf www.antikoerper-online.de finden Sie aktuell 92 Bone Morphogenetic Protein 2 (BMP2) Proteine von 23 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen BMP2 Antikörper (325) und BMP2 Kits (140) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 574 BMP2 Produkte verfügbar.
Synonyme:
2610024H22Rik, AI467020, AL117858, AW546137, BB189135, BDA2, BMP-2, BMP2, Bmp2a, BMPR-2, BMPR-II, BMPRII, BRK-3, Gm20272, xBMP-2, xbmp2
alle Proteine anzeigen Gen GeneID UniProt
BMP2 650 P12643
BMP2 12156 P21274
BMP2 29373 P49001

Weitere Synonyme anzeigen

BMP2 Proteine (BMP2) nach Spezies

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Am meisten referenzierte BMP2 Proteine

  1. Human BMP2 Protein expressed in Escherichia coli (E. coli) - ABIN2002823 : Wozney, Rosen, Celeste, Mitsock, Whitters, Kriz, Hewick, Wang: Novel regulators of bone formation: molecular clones and activities. in Science (New York, N.Y.) 1989 (PubMed)
    Zeige alle 5 Referenzen für 2002823

  2. Human BMP2 Protein expressed in Escherichia coli (E. coli) - ABIN413080 : Sharapova, Kotnova, Galushkina, Lavrova, Poletaeva, Tukhvatulin, Tukhvatullin, Semikhin, Gromov, Soboleva, Ershova, Za?tsev, Sergienko, Lunin, Kariagina: [Production of the recombinant human bone morphogenetic protein-2 in Escherichia coli and testing of its biological activity in vitro and in vivo]. in Molekuliarnaia biologiia 2011 (PubMed)
    Zeige alle 4 Referenzen für 413080

  3. Zebrafish (Danio rerio) BMP2 Protein expressed in Escherichia coli (E. coli) - ABIN2008807 : Kawamura, Kizaki, Yamato, Uchida, Fukuchi, Hattori, Koseki, Nishihara, Ikeda: Bone morphogenetic protein-2 induces apoptosis in human myeloma cells with modulation of STAT3. in Blood 2000 (PubMed)
    Zeige alle 4 Referenzen für 2008807

  4. Human BMP2 Protein expressed in Escherichia coli (E. coli) - ABIN2180654 : Lai, Fong, Fu, Yang, Tang: Osteoblasts-derived BMP-2 enhances the motility of prostate cancer cells via activation of integrins. in The Prostate 2008 (PubMed)
    Zeige alle 2 Referenzen für 2180654

  5. Human BMP2 Protein expressed in Escherichia coli (E. coli) - ABIN1098803 : Chen, Zhao, Mundy: Bone morphogenetic proteins. in Growth factors (Chur, Switzerland) 2004 (PubMed)

Weitere Proteine zu BMP2 Interaktionspartnern

Horse (Equine) Bone Morphogenetic Protein 2 (BMP2) Interaktionspartner

  1. The effect of bone morphogenetic protein (BMP) 12 and BMP2 expression on differentiation of bone marrow-derived mesenchymal stem cells and superficial digital flexor tenocytes is reported.

Xenopus laevis Bone Morphogenetic Protein 2 (BMP2) Interaktionspartner

  1. Bone morphogenetic protein inhibition is sufficient for neural induction in vivo, and that in the absence of ventral BMPs, Spemann organizer signals are not required for brain formation.

  2. Bmp antagonists and morpholinos designed against Bmp4, Bmp2, and Bmp7 demonstrate that Bmp signaling is critical for ventral, but not dorsoanterior endoderm formation

Pig (Porcine) Bone Morphogenetic Protein 2 (BMP2) Interaktionspartner

  1. High yield isolation of BMP-2 from bone and in vivo activity of a combination of BMP-2/TGF-beta1 (zeige TGFB1 Proteine).

  2. Report temporal regulation of BMP2 mRNA expression in the oocyte, granulosa and theca cells of developing preovulatory follicles in the pig.

  3. Regional variation of periosteal activity at the mandibular ramus is regulated by differential induction of BMP2.

  4. The effects of soy- and cow's milk-based formulas compared to nursing on bone development through BMP2 expression in neonatal pigs are reported.

Human Bone Morphogenetic Protein 2 (BMP2) Interaktionspartner

  1. RANKL (zeige TNFSF11 Proteine) promotes VC by inducing BMP-2 release from HAECs

  2. KDM5A (zeige KDM5A Proteine)-mediated H3K4me3 modification participated in the etiology of osteoporosis and may provide new strategies to improve the clinical efficacy of BMP2 in osteoporotic conditions.

  3. Data suggest pituitary cells secrete factor (TSP1) that binds to and inhibits action of BMP2 and BMP4; von Willebrand type C domain of TSP1 is likely responsible for this BMP2/4-binding activity. These studies were initially conducted using cultured cells from ovine pituitary gland and mouse cell line; interactions were confirmed using recombinant human proteins. (TSP1 = thrombospondin-1; BMP = bone morphogenetic protein)

  4. Structural analyses of von Willebrand factor (zeige VWF Proteine) C domains of collagen 2A and CCN3 (zeige NOV Proteine) reveal an alternative mode of binding to bone morphogenetic protein-2

  5. molecular basis of both activities was shown in two different cellular models to clearly rely on the properties of the investigated BMP2 muteins to compete for the binding of Activin A to the Activin type II receptors

  6. Results indicate that implantation of recombinant human BMP-2/absorbable collagen sponges on the lumbar spine triggers potent neuroinflammatory responses in adjacent dorsal root ganglia. Importantly, however, these BMP-2 effects may be partially mediated through a response to the absorbable collagen sponges.

  7. Single nucleotide polymorphism in the BMP2 gene is associated with inflammation in chronic kidney disease.

  8. miR (zeige MLXIP Proteine)-98 may regulate osteogenic differentiation of human bone mesenchymal stromal cells by targeting BMP2.

  9. fibrillar fibronectin (zeige FN1 Proteine) on this polymer, but not a globular conformation obtained on control polymers, promotes synergistic presentation of integrin-binding sites and bound bone morphogenetic protein 2 (BMP-2), which enhances mesenchymal stem cell osteogenesis in vitro and drives full regeneration of a nonhealing bone defect in vivo at low GF concentrations.

  10. Study indicated that rs15705 and rs3178250, located at the BMP2 3'- UTR and potentially affecting the miRNA-mRNA interaction, namely with miR (zeige MLXIP Proteine)-1273d or miR (zeige MLXIP Proteine)-4639-5p, are associated with an increased risk of non-syndromic tooth agenesis.

Mouse (Murine) Bone Morphogenetic Protein 2 (BMP2) Interaktionspartner

  1. results indicate that Alx3 (zeige ALX3 Proteine) expression is enhanced by BMP-2 via the BMP receptors mediated-Smad (zeige SMAD1 Proteine) signaling and that Alx3 (zeige ALX3 Proteine) is a positive regulator of osteoblast differentiation induced by BMP-2

  2. KDM5A (zeige KDM5A Proteine)-mediated H3K4me3 modification participated in the etiology of osteoporosis and may provide new strategies to improve the clinical efficacy of BMP2 in osteoporotic conditions.

  3. BMP2 expression in the endocardial lineage is essential for the distal outgrowth, maturation and remodeling of atrioventricular endocardial cushions.

  4. the effect of titanium (Ti) with nanotopography (Nano) on the endogenous expression of BMP-2 and BMP-4 (zeige BMP4 Proteine) and the relevance of this process to the nanotopography-induced osteoblast differentiation.

  5. Dynamin (zeige DNM1 Proteine)-dependent endocytosis of Bone Morphogenetic Protein2 (BMP2) and its receptors is dispensable for the initiation of Smad (zeige SMAD1 Proteine) signaling

  6. can increase [Ca(2 (zeige CA2 Proteine)+) ]i through extracellular calcium influx regulated by FAK (zeige PTK2 Proteine) and ALP (zeige CCL21A Proteine) and can deplete endoplasmic reticulum calcium through Src (zeige SRC Proteine) signaling simultaneously

  7. Our studies suggest operation of an auto/paracrine mechanism by which BMP-2 secreted by M1 macrophages maintains constitutive activation of a BMP-2 receptor/SMAD1 (zeige SMAD1 Proteine)/5 signaling axis.

  8. Genetic inactivation of hepatic angiocrine Bmp2 signaling in Stab2 (zeige STAB2 Proteine)-Cre mice caused massive iron overload in the liver and increased serum iron levels and iron deposition in several organs similar to classic hereditary hemochromatosis (zeige HFE Proteine); these changes were mediated by decreased hepatic expression of hepcidin (zeige HAMP Proteine), a key regulator of iron homeostasis.

  9. Actin cytoskeleton depolymerization inhibites BMP2 signaling via blocking of Smad (zeige SMAD1 Proteine) by dephosphorylated CNN1 (zeige CNN1 Proteine) in osteoblast cells under simulated microgravity.

  10. Disrupting BMPR2 (zeige BMPR2 Proteine) impairs TGFbeta1 (zeige TGFB1 Proteine)- and BMP4 (zeige BMP4 Proteine)-mediated elastic fiber assembly and is of pathophysiologic significance in pulmonary arterial hypertension.

Rabbit Bone Morphogenetic Protein 2 (BMP2) Interaktionspartner

  1. The transfecting capability of a BMP-2 specific vector is examined and supports the idea that BMP-2 might diminish osseointegration and implant fixation.

  2. While BMP2 expression begins at (pregastrulation) stage 1 in the hypoblast, BMP4 (zeige BMP4 Proteine) expression commences--distinctly delayed compared to the mouse--diffusely at (pregastrulation) stage 2; from stage 3 onwards.

  3. Maxillary sinus floor elevation using BMP-2 gene-modified bone marrow stromal cells and TCP in rabbits

  4. Data show that BMP-2, BMP-4 (zeige BMP4 Proteine), and BMP-7 (zeige BMP7 Proteine), noggin (zeige NOG Proteine), and chordin (zeige CHRD Proteine) were colocalized in rimming osteoblasts, osteoclasts, and chondrocytes.

  5. BMP2 is not suitable to regenerate osteochondral lesions completely

Cow (Bovine) Bone Morphogenetic Protein 2 (BMP2) Interaktionspartner

  1. both FSH (zeige BRD2 Proteine) and BMP-2 reduced follicular mRNA expression of GDF9 (zeige GDF9 Proteine) and NLRP5 when compared to follicles cultured in media containing only FSH (zeige BRD2 Proteine)

  2. The BMP2/4 (zeige BMP4 Proteine) ligand and receptor system presides within bovine trophectoderm prior to uterine attachment.

  3. concluded that a bone morphogenetic protein (BMP)-signaling system, consisting of BMP2, BMP4, type II and I receptors, is present in bovine antral follicles and plays a role in development and functioning of follicles rather than oocyte maturation

BMP2 Protein Überblick

Protein Überblick

The protein encoded by this gene belongs to the transforming growth factor-beta (TGFB) superfamily. The encoded protein acts as a disulfide-linked homodimer and induces bone and cartilage formation.

Alternative names and synonyms associated with BMP2

  • bone morphogenetic protein 2 (BMP2)
  • bone morphogenetic protein 2 (bmp2-b)
  • bone morphogenetic protein 2 (bmp2)
  • Bone morphogenetic protein 2 (bmp2)
  • bone morphogenetic protein 2 (Bmp2)
  • bone morphogenetic protein 2 (BMP-2)
  • bone morphogenetic protein receptor, type II (serine/threonine kinase) (Bmpr2)
  • 2610024H22Rik Protein
  • AI467020 Protein
  • AL117858 Protein
  • AW546137 Protein
  • BB189135 Protein
  • BDA2 Protein
  • BMP-2 Protein
  • BMP2 Protein
  • Bmp2a Protein
  • BMPR-2 Protein
  • BMPR-II Protein
  • BMPRII Protein
  • BRK-3 Protein
  • Gm20272 Protein
  • xBMP-2 Protein
  • xbmp2 Protein

Bezeichner auf Proteinebene für BMP2

bone morphogenetic protein 2 precursor (BMP-2) (BMP-2A) , BMP-2-II , bone morphogenetic protein 2 B , bone morphogenetic protein 2-B , bone morphogenetic protein 2 , morphogen , Bone morphogenetic protein 2 , bone morphogenetic protein 2-like , BMP-2A , bone morphogenetic protein 2A , BMP-2 , BMP type II receptor , BMP type-2 receptor , bone morphogenetic protein receptor type-2 , bone morphogenic protein receptor, type II (serine/threonine kinase)

GENE ID SPEZIES
100051701 Equus caballus
397873 Xenopus laevis
458090 Pan troglodytes
494462 Sus scrofa
548717 Xenopus (Silurana) tropicalis
718330 Macaca mulatta
100218108 Taeniopygia guttata
100301987 Felis catus
100380549 Salmo salar
100408260 Callithrix jacchus
100460853 Pongo abelii
650 Homo sapiens
12156 Mus musculus
29373 Rattus norvegicus
100860831 Capra hircus
100157103 Sus scrofa
477162 Canis lupus familiaris
100009349 Oryctolagus cuniculus
378779 Gallus gallus
615037 Bos taurus
100732974 Cavia porcellus
443173 Ovis aries
12168 Mus musculus
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